Question 1

A CSF specimen,in which there is uneven distribution of blood among the three tubes and clots are detected,is an indication of:

Accepted Answer

A)  Meningitis 
B)  Cerebral hemorrhage 
C)  Multiple sclerosis 
D)  Traumatic tap 
A)  Meningitis 
B)  Cerebral hemorrhage 
C)  Multiple sclerosis 
D)  Traumatic tap

Question 2

The normal CSF protein is:

Accepted Answer

A)  15 to 45 mg/dL 
B)  15 to 45 g/dL 
C)  50 to 100 mg/dL 
D)  50 to 100 g/dL 
A)  15 to 45 mg/dL 
B)  15 to 45 g/dL 
C)  50 to 100 mg/dL 
D)  50 to 100 g/dL

Question 3

If protein electrophoresis was performed on both serum and CSF,which of the following components would have a higher ratio to total protein in the CSF than in the serum?

Accepted Answer

A)  Transferrin 
B)  Ceruloplasmin 
C)  Albumin 
D)  Prealbumin 
A)  Transferrin 
B)  Ceruloplasmin 
C)  Albumin 
D)  Prealbumin

Question 4

The recommended serologic test for the diagnosis of neurosyphilis is the rapid plasma reagin test.

Accepted Answer

A) True 
 B)False

Question 5

Increased CSF eosinophils are associated with:

Accepted Answer

A)  Multiple sclerosis 
B)  Introduction of foreign material 
C)  Human immunodeficiency virus 
D)  Viral meningitis 
A)  Multiple sclerosis 
B)  Introduction of foreign material 
C)  Human immunodeficiency virus 
D)  Viral meningitis

Question 6

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed.
-Based on the information provided,what type of meningitis would most probably be suspected in this patient?

Accepted Answer

A)  Fungal 
B)  Viral 
C)  Bacterial 
D)  Tubercular 
A)  Fungal 
B)  Viral 
C)  Bacterial 
D)  Tubercular

Question 7

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed.
-Based on the information provided,what diagnostically significant observation might be made on the Gram stain?

Accepted Answer

A)  Gram-positive cocci 
B)  Gram-negative rods 
C)  Starburst microbial pattern 
D)  Fungal mycelia 
A)  Gram-positive cocci 
B)  Gram-negative rods 
C)  Starburst microbial pattern 
D)  Fungal mycelia

Question 8

Three tubes of CSF are submitted to the laboratory.They are numbered 1,2,and 3 and show blood in all tubes but decreasing in amount as one inspects tubes 1 through 3.This observation should be interpreted as:

Accepted Answer

A)  The tubes were numbered in the wrong sequence, as one would expect increasing amounts of blood 
B)  A traumatic or bloody tap is suspected and, in all likelihood, no pathogenic significance should be attached to the presence of the blood 
C)  The pathologic presence of RBCs and reported to the supervisor immediately 
D)  A pathologic presence of RBCs, but because the RBC morphology is normal there is minimal importance 
A)  The tubes were numbered in the wrong sequence, as one would expect increasing amounts of blood 
B)  A traumatic or bloody tap is suspected and, in all likelihood, no pathogenic significance should be attached to the presence of the blood 
C)  The pathologic presence of RBCs and reported to the supervisor immediately 
D)  A pathologic presence of RBCs, but because the RBC morphology is normal there is minimal importance

Question 9

The third tube of CSF collected from a lumbar puncture should be used for:

Accepted Answer

A)  Chemistry tests 
B)  Cytology examination 
C)  Microbiology tests 
D)  Hematology tests 
A)  Chemistry tests 
B)  Cytology examination 
C)  Microbiology tests 
D)  Hematology tests

Question 10

White blood cell (WBC)counts on clear CSF specimens are performed:

Accepted Answer

A)  Using centrifuged specimens 
B)  Only if multiple sclerosis is suspected 
C)  On undiluted specimens if there is no cell overlapping 
D)  On specimens diluted 1:200 with gentian violet 
A)  Using centrifuged specimens 
B)  Only if multiple sclerosis is suspected 
C)  On undiluted specimens if there is no cell overlapping 
D)  On specimens diluted 1:200 with gentian violet

Question 11

Nucleated red blood cells (RBCs)seen in the CSF indicate:

Accepted Answer

A)  Recent cerebral hemorrhage 
B)  Acute leukemia 
C)  A ventricular rather than a lumbar puncture 
D)  Bone marrow contamination from the puncture 
A)  Recent cerebral hemorrhage 
B)  Acute leukemia 
C)  A ventricular rather than a lumbar puncture 
D)  Bone marrow contamination from the puncture

Question 12

The normal CSF glucose is:

Accepted Answer

A)  25 to 50 mg/dL 
B)  80 to 120 mg/dL 
C)  60% to 70% of the blood glucose 
D)  10% to 20% higher than the blood glucose 
A)  25 to 50 mg/dL 
B)  80 to 120 mg/dL 
C)  60% to 70% of the blood glucose 
D)  10% to 20% higher than the blood glucose

Question 13

A report of many gram-positive cocci on a clear CSF sample with a normal cell count may be the result of:

Accepted Answer

A)  An incorrect cell count 
B)  Effective antibiotic treatment 
C)  Use of contaminated albumin in the cytocentrifuge 
D)  Use of recycled cytocentrifuge chambers 
A)  An incorrect cell count 
B)  Effective antibiotic treatment 
C)  Use of contaminated albumin in the cytocentrifuge 
D)  Use of recycled cytocentrifuge chambers

Question 14

A positive cryptococcal antigen test with a negative India ink preparation may indicate:

Accepted Answer

A)  Bacterial rather than fungal meningitis 
B)  Tubercular meningitis 
C)  The failure to inactivate the CSF 
D)  The presence of rheumatoid factor 
A)  Bacterial rather than fungal meningitis 
B)  Tubercular meningitis 
C)  The failure to inactivate the CSF 
D)  The presence of rheumatoid factor

Question 15

CSF is formed in the _______________ and reabsorbed by the _______________.

Accepted Answer

A)  Ventricles, spinal cord 
B)  Choroid plexus, arachnoid granulations 
C)  Arachnoid space, blood-brain barrier 
D)  Blood-brain barrier, arachnoid granulations 
A)  Ventricles, spinal cord 
B)  Choroid plexus, arachnoid granulations 
C)  Arachnoid space, blood-brain barrier 
D)  Blood-brain barrier, arachnoid granulations

Question 16

Myelin basic protein is measured in the CSF to assess the condition of patients with:

Accepted Answer

A)  Cerebral hemorrhage 
B)  Multiple sclerosis 
C)  Bacterial meningitis 
D)  Neurosyphilis 
A)  Cerebral hemorrhage 
B)  Multiple sclerosis 
C)  Bacterial meningitis 
D)  Neurosyphilis

Question 17

The lowest levels of CSF lactate can be found in patients with:

Accepted Answer

A)  Bacterial meningitis 
B)  Viral meningitis 
C)  Tubercular meningitis 
D)  Fungal meningitis 
A)  Bacterial meningitis 
B)  Viral meningitis 
C)  Tubercular meningitis 
D)  Fungal meningitis

Question 18

Oligoclonal bands are significant in the diagnosis of multiple sclerosis when:

Accepted Answer

A)  They are seen in both the serum and CSF 
B)  At least five bands are seen in the CSF 
C)  They are seen in the CSF and not in the serum 
D)  They appear in both the albumin and globulin fractions of serum and CSF 
A)  They are seen in both the serum and CSF 
B)  At least five bands are seen in the CSF 
C)  They are seen in the CSF and not in the serum 
D)  They appear in both the albumin and globulin fractions of serum and CSF

Question 19

A CSF glutamine level is an indirect measure of CSF:

Accepted Answer

A)  Lactate 
B)  Hypoxia 
C)  Ammonia 
D)  Creatine kinase 
A)  Lactate 
B)  Hypoxia 
C)  Ammonia 
D)  Creatine kinase

Question 20

An IgG index greater than 0.77 indicates:

Accepted Answer

A)  Synthesis of IgG within the CNS 
B)  Alterations of the blood-brain barrier 
C)  Active demyelination of neural tissue 
D)  Increased reabsorption of IgG from the peripheral blood 
A)  Synthesis of IgG within the CNS 
B)  Alterations of the blood-brain barrier 
C)  Active demyelination of neural tissue 
D)  Increased reabsorption of IgG from the peripheral blood

A CSF specimen,in which there is uneven distribution of blood among the three tubes and clots are detected,is an indication of:

The normal CSF protein is:

If protein electrophoresis was performed on both serum and CSF,which of the following components would have a higher ratio to total protein in the CSF than in the serum?

The recommended serologic test for the diagnosis of neurosyphilis is the rapid plasma reagin test.

Increased CSF eosinophils are associated with:

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed. -Based on the information provided,what type of meningitis would most probably be suspected in this patient?

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed. -Based on the information provided,what diagnostically significant observation might be made on the Gram stain?

Three tubes of CSF are submitted to the laboratory.They are numbered 1,2,and 3 and show blood in all tubes but decreasing in amount as one inspects tubes 1 through 3.This observation should be interpreted as:

The third tube of CSF collected from a lumbar puncture should be used for:

White blood cell (WBC)counts on clear CSF specimens are performed:

Nucleated red blood cells (RBCs)seen in the CSF indicate:

The normal CSF glucose is:

A report of many gram-positive cocci on a clear CSF sample with a normal cell count may be the result of:

A positive cryptococcal antigen test with a negative India ink preparation may indicate:

CSF is formed in the _ and reabsorbed by the _.

Myelin basic protein is measured in the CSF to assess the condition of patients with:

The lowest levels of CSF lactate can be found in patients with:

Oligoclonal bands are significant in the diagnosis of multiple sclerosis when:

A CSF glutamine level is an indirect measure of CSF:

An IgG index greater than 0.77 indicates:

Safety and Quality Assessment

Introduction to Urinalysis

Renal Function

Physical Examination of Urine

Chemical Examination of Urine

Microscopic Examination of Urine

Renal Disease

Urine Screening for Metabolic Disorders

Semen

Synovial Fluid

Serous Fluid

Amniotic Fluid

Fecal Analysis

Vaginal Secretions

Filters

Exam 9: Cerebrospinal Fluid

A CSF specimen,in which there is uneven distribution of blood among the three tubes and clots are detected,is an indication of:

The normal CSF protein is:

If protein electrophoresis was performed on both serum and CSF,which of the following components would have a higher ratio to total protein in the CSF than in the serum?

The recommended serologic test for the diagnosis of neurosyphilis is the rapid plasma reagin test.

Increased CSF eosinophils are associated with:

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed. -Based on the information provided,what type of meningitis would most probably be suspected in this patient?

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed. -Based on the information provided,what diagnostically significant observation might be made on the Gram stain?

Three tubes of CSF are submitted to the laboratory.They are numbered 1,2,and 3 and show blood in all tubes but decreasing in amount as one inspects tubes 1 through 3.This observation should be interpreted as:

The third tube of CSF collected from a lumbar puncture should be used for:

White blood cell (WBC)counts on clear CSF specimens are performed:

Nucleated red blood cells (RBCs)seen in the CSF indicate:

The normal CSF glucose is:

A report of many gram-positive cocci on a clear CSF sample with a normal cell count may be the result of:

A positive cryptococcal antigen test with a negative India ink preparation may indicate:

CSF is formed in the _______________ and reabsorbed by the _______________.

Myelin basic protein is measured in the CSF to assess the condition of patients with:

The lowest levels of CSF lactate can be found in patients with:

Oligoclonal bands are significant in the diagnosis of multiple sclerosis when:

A CSF glutamine level is an indirect measure of CSF:

An IgG index greater than 0.77 indicates:

Safety and Quality Assessment

Introduction to Urinalysis

Renal Function

Physical Examination of Urine

Chemical Examination of Urine

Microscopic Examination of Urine

Renal Disease

Urine Screening for Metabolic Disorders

Semen

Synovial Fluid

Serous Fluid

Amniotic Fluid

Fecal Analysis

Vaginal Secretions

Filters

CSF is formed in the _ and reabsorbed by the _.