Question 1

Multiple osteomas and odontomas seen with Gardner syndrome can cause which oral complication?

Accepted Answer

A)  Teeth fail to erupt. 
B)  Teeth demonstrate increased mobility. 
C)  Increased supernumerary teeth 
D)  Teeth exfoliate prematurely. 
A)  Teeth fail to erupt. 
B)  Teeth demonstrate increased mobility. 
C)  Increased supernumerary teeth 
D)  Teeth exfoliate prematurely.

Question 2

Snow-capped amelogenesis imperfecta is a variation of type _____ amelogenesis imperfecta.

Accepted Answer

A)  I: hypoplastic 
B)  II: hypocalcified 
C)  III: hypomaturation 
D)  IV: hypoplastic-hypomaturation 
A)  I: hypoplastic 
B)  II: hypocalcified 
C)  III: hypomaturation 
D)  IV: hypoplastic-hypomaturation

Question 3

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.
-Trisomy 13

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 4

The areas of bony radiolucency seen in cherubism

Accepted Answer

A)  resemble a central giant cell granuloma when seen under the microscope. 
B)  occur in place of the teeth, and radiographs will reveal complete anodontia. 
C)  will increase in size as the patient matures, even until the seventh or eighth decade of life. 
D)  will resolve, leaving the patient without any sign of facial deformity later in life. 
A)  resemble a central giant cell granuloma when seen under the microscope. 
B)  occur in place of the teeth, and radiographs will reveal complete anodontia. 
C)  will increase in size as the patient matures, even until the seventh or eighth decade of life. 
D)  will resolve, leaving the patient without any sign of facial deformity later in life.

Question 5

Neurofibromatosis of von Recklinghausen is characterized by

Accepted Answer

A)  multiple neurofibromas appearing as macules of various sizes. 
B)  inevitable malignant transformation. 
C)  oral involvement in about 90% of patients. 
D)  café au lait pigmentation of the skin in 90% of patients. 
A)  multiple neurofibromas appearing as macules of various sizes. 
B)  inevitable malignant transformation. 
C)  oral involvement in about 90% of patients. 
D)  café au lait pigmentation of the skin in 90% of patients.

Question 6

For autosomal-dominant inheritance, _____ pertains to the degree to which an individual is affected.

Accepted Answer

A)  penetrance 
B)  expressivity 
C)  heterogeneity 
D)  consanguinity 
A)  penetrance 
B)  expressivity 
C)  heterogeneity 
D)  consanguinity

Question 7

Hypohidrotic ectodermal dysplasia is characterized by

Accepted Answer

A)  hypodontia, hypotrichosis, and hypohidrosis. 
B)  hyperdontia, hypotrichosis, and hypohidrosis. 
C)  hypodontia, hypertrichosis, and hyperhidrosis. 
D)  hyperdontia, hypertrichosis, and hyperhidrosis. 
A)  hypodontia, hypotrichosis, and hypohidrosis. 
B)  hyperdontia, hypotrichosis, and hypohidrosis. 
C)  hypodontia, hypertrichosis, and hyperhidrosis. 
D)  hyperdontia, hypertrichosis, and hyperhidrosis.

Question 8

Inactivation of the genetic activity of one of the X chromosomes in each cell of a female embryo during the early period of embryonic development is referred to as

Accepted Answer

A)  Barr body. 
B)  nucleotide. 
C)  karyotype. 
D)  the Lyon hypothesis. 
A)  Barr body. 
B)  nucleotide. 
C)  karyotype. 
D)  the Lyon hypothesis.

Question 9

White sponge nevus is characterized by a white, corrugated, soft, folding oral mucosa always affecting _____ mucosa.

Accepted Answer

A)  attached 
B)  lingual 
C)  buccal 
D)  tonsillar 
A)  attached 
B)  lingual 
C)  buccal 
D)  tonsillar

Question 10

A patient with Papillon-Lefèvre syndrome will show a marked gingivoperiodontal inflammatory condition in the primary teeth at about _____ years of age.

Accepted Answer

A)  0 to 0.5 
B)  1.5 to 2 
C)  4 to 6 
D)  8 to 9 
A)  0 to 0.5 
B)  1.5 to 2 
C)  4 to 6 
D)  8 to 9

Question 11

Pegged or absent maxillary lateral incisors

Accepted Answer

A)  affect the secondary but not primary dentition. 
B)  have a prevalence of 10% in the white population. 
C)  are accompanied by congenitally lacking premolar teeth in 10% to 20% of the population. 
D)  are generally an autosomal-recessive trait with variable expressivity. 
A)  affect the secondary but not primary dentition. 
B)  have a prevalence of 10% in the white population. 
C)  are accompanied by congenitally lacking premolar teeth in 10% to 20% of the population. 
D)  are generally an autosomal-recessive trait with variable expressivity.

Question 12

Hypophosphatasia is characterized by

Accepted Answer

A)  an increase in serum alkaline phosphatase levels. 
B)  abnormal formation of enamel and dentin. 
C)  exfoliation of teeth without evidence of periodontal or gingival disease. 
D)  an autosomal-dominant inheritance pattern. 
A)  an increase in serum alkaline phosphatase levels. 
B)  abnormal formation of enamel and dentin. 
C)  exfoliation of teeth without evidence of periodontal or gingival disease. 
D)  an autosomal-dominant inheritance pattern.

Question 13

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.
-Position occupied by a gene on a chromosome

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

Question 14

Which syndrome is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Accepted Answer

A)  Osler-Rendu-Parkes Weber syndrome 
B)  Ellis-van Creveld syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome 
A)  Osler-Rendu-Parkes Weber syndrome 
B)  Ellis-van Creveld syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome

Question 15

Which statement about the hereditary opalescent form of dentinogenesis imperfecta is true?

Accepted Answer

A)  It is associated with taurodontic teeth. 
B)  Teeth have bulbous crowns with a color that varies from opalescent brown to brownish blue. 
C)  Large pulp chambers and root canals are seen on radiographs. 
D)  Roots are long and thick with periapical radiopacities. 
A)  It is associated with taurodontic teeth. 
B)  Teeth have bulbous crowns with a color that varies from opalescent brown to brownish blue. 
C)  Large pulp chambers and root canals are seen on radiographs. 
D)  Roots are long and thick with periapical radiopacities.

Question 16

The gap 2 (G2) phase of mitosis

Accepted Answer

A)  begins when mitotic division ends. 
B)  ends when mitotic division begins. 
C)  precedes the S phase. 
D)  is when replication of DNA takes place. 
A)  begins when mitotic division ends. 
B)  ends when mitotic division begins. 
C)  precedes the S phase. 
D)  is when replication of DNA takes place.

Question 17

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.
-Klinefelter

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 18

Where is the most common intraoral site for the development of neurofibromas in a patient with von Recklinghausen disease?

Accepted Answer

A)  Floor of the mouth 
B)  Labial commissures 
C)  Palate 
D)  Lateral borders of the tongue 
A)  Floor of the mouth 
B)  Labial commissures 
C)  Palate 
D)  Lateral borders of the tongue

Question 19

For parents who are carriers of the same recessive trait, the chance of giving birth to an affected child is _____%.

Accepted Answer

A)  0 
B)  25 
C)  50 
D)  100 
A)  0 
B)  25 
C)  50 
D)  100

Question 20

If both loci for blood are AO, the

Accepted Answer

A)  person is said to have blood group O. 
B)  person is said to have blood group A. 
C)  person would be homozygous. 
D)  characteristic is recessive. 
A)  person is said to have blood group O. 
B)  person is said to have blood group A. 
C)  person would be homozygous. 
D)  characteristic is recessive.

Multiple osteomas and odontomas seen with Gardner syndrome can cause which oral complication?

Snow-capped amelogenesis imperfecta is a variation of type _____ amelogenesis imperfecta.

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Trisomy 13

The areas of bony radiolucency seen in cherubism

Neurofibromatosis of von Recklinghausen is characterized by

For autosomal-dominant inheritance, _____ pertains to the degree to which an individual is affected.

Hypohidrotic ectodermal dysplasia is characterized by

Inactivation of the genetic activity of one of the X chromosomes in each cell of a female embryo during the early period of embryonic development is referred to as

White sponge nevus is characterized by a white, corrugated, soft, folding oral mucosa always affecting _____ mucosa.

A patient with Papillon-Lefèvre syndrome will show a marked gingivoperiodontal inflammatory condition in the primary teeth at about _____ years of age.

Pegged or absent maxillary lateral incisors

Hypophosphatasia is characterized by

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Position occupied by a gene on a chromosome

Which syndrome is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Which statement about the hereditary opalescent form of dentinogenesis imperfecta is true?

The gap 2 (G₂) phase of mitosis

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Klinefelter

Where is the most common intraoral site for the development of neurofibromas in a patient with von Recklinghausen disease?

For parents who are carriers of the same recessive trait, the chance of giving birth to an affected child is _____%.

If both loci for blood are AO, the

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

Multiple osteomas and odontomas seen with Gardner syndrome can cause which oral complication?

Snow-capped amelogenesis imperfecta is a variation of type _____ amelogenesis imperfecta.

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Trisomy 13

The areas of bony radiolucency seen in cherubism

Neurofibromatosis of von Recklinghausen is characterized by

For autosomal-dominant inheritance, _____ pertains to the degree to which an individual is affected.

Hypohidrotic ectodermal dysplasia is characterized by

Inactivation of the genetic activity of one of the X chromosomes in each cell of a female embryo during the early period of embryonic development is referred to as

White sponge nevus is characterized by a white, corrugated, soft, folding oral mucosa always affecting _____ mucosa.

A patient with Papillon-Lefèvre syndrome will show a marked gingivoperiodontal inflammatory condition in the primary teeth at about _____ years of age.

Pegged or absent maxillary lateral incisors

Hypophosphatasia is characterized by

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Position occupied by a gene on a chromosome

Which syndrome is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Which statement about the hereditary opalescent form of dentinogenesis imperfecta is true?

The gap 2 (G2) phase of mitosis

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Klinefelter

Where is the most common intraoral site for the development of neurofibromas in a patient with von Recklinghausen disease?

For parents who are carriers of the same recessive trait, the chance of giving birth to an affected child is _____%.

If both loci for blood are AO, the

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters

The gap 2 (G₂) phase of mitosis