Question 1

Intestinal polyps seen with Peutz-Jeghers syndrome are

Accepted Answer

A)  associated with inevitable malignant transformation into adenocarcinomas. 
B)  hamartomas. 
C)  caused by the adenomatous polyposis coli (AP
C)  gene located on the long arm of chromosome 5. 
D)  associated with osteomas in various bones, especially the frontal bones, mandible, and maxilla. 
A)  associated with inevitable malignant transformation into adenocarcinomas. 
B)  hamartomas. 
C)  caused by the adenomatous polyposis coli (AP
C)  gene located on the long arm of chromosome 5. 
D)  associated with osteomas in various bones, especially the frontal bones, mandible, and maxilla.

Question 2

A patient with _____ will have a mouth that appears fishlike, with downward sloping of the lip commissures.

Accepted Answer

A)  osteogenesis imperfecta 
B)  mandibulofacial dysostosis 
C)  cherubism 
D)  cleidocranial dysplasia 
A)  osteogenesis imperfecta 
B)  mandibulofacial dysostosis 
C)  cherubism 
D)  cleidocranial dysplasia

Question 3

__________ is characterized by very large, pyramid-shaped molars with large pulp chambers.

Accepted Answer

A)  Amelogenesis imperfecta 
B)  Dentinogenesis imperfecta 
C)  Taurodontism 
D)  Dentin dysplasia 
A)  Amelogenesis imperfecta 
B)  Dentinogenesis imperfecta 
C)  Taurodontism 
D)  Dentin dysplasia

Question 4

Frontal bossing, depressed nasal bridge, protuberant lips, and almost complete lack of scalp hair are characteristic of a person with which condition?

Accepted Answer

A)  Hypophosphatemic vitamin D-resistant rickets 
B)  Hypophosphatasia 
C)  Hypohidrotic ectodermal dysplasia 
D)  Dentin dysplasia 
A)  Hypophosphatemic vitamin D-resistant rickets 
B)  Hypophosphatasia 
C)  Hypohidrotic ectodermal dysplasia 
D)  Dentin dysplasia

Question 5

What age are all of the permanent teeth typically lost in a patient with Papillon-Lefèvre syndrome?

Accepted Answer

A)  10 
B)  14 
C)  22 
D)  28 
A)  10 
B)  14 
C)  22 
D)  28

Question 6

For autosomal-dominant inheritance

Accepted Answer

A)  males will be affected more often than females. 
B)  the risk of having an affected offspring is 25% when a person has a gene for the condition. 
C)  all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance. 
D)  an individual can carry a gene with a dominant effect without presenting any clinical manifestations. 
A)  males will be affected more often than females. 
B)  the risk of having an affected offspring is 25% when a person has a gene for the condition. 
C)  all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance. 
D)  an individual can carry a gene with a dominant effect without presenting any clinical manifestations.

Question 7

The gap 1, S, and gap 2 phases are part of what type of cell division?

Accepted Answer

A)  First meiosis 
B)  Second meiosis 
C)  Mitosis 
D)  Hypohidrosis 
A)  First meiosis 
B)  Second meiosis 
C)  Mitosis 
D)  Hypohidrosis

Question 8

Oral manifestations seen with a person with Down syndrome include the following except one. Which is the exception?

Accepted Answer

A)  Fissured tongue 
B)  Gingival and periodontal disease 
C)  Hypodontia 
D)  Macrodontia 
A)  Fissured tongue 
B)  Gingival and periodontal disease 
C)  Hypodontia 
D)  Macrodontia

Question 9

Chromosomes line up at the equatorial plate during the _____ stage of mitosis.

Accepted Answer

A)  telophase 
B)  metaphase 
C)  prophase 
D)  anaphase 
A)  telophase 
B)  metaphase 
C)  prophase 
D)  anaphase

Question 10

According to the Lyon hypothesis during the early period of embryonic development, the

Accepted Answer

A)  genetic activity of both of the X chromosomes in each cell of a female embryo is inactivated. 
B)  genetic activity of one of the X chromosomes in each cell of a female embryo is inactivated. 
C)  genetic activity of the Y chromosome in each cell of a male embryo is inactivated. 
D)  inactivated chromosome forms a structure known as the pronucleus. 
A)  genetic activity of both of the X chromosomes in each cell of a female embryo is inactivated. 
B)  genetic activity of one of the X chromosomes in each cell of a female embryo is inactivated. 
C)  genetic activity of the Y chromosome in each cell of a male embryo is inactivated. 
D)  inactivated chromosome forms a structure known as the pronucleus.

Question 11

Your patient presents with hypodontia, hypohidrosis, and nearly complete lack of sweat and sebaceous glands. Also noticeable is a lack of eyelashes and eyebrows. Which hereditary condition is present?

Accepted Answer

A)  Amelogenesis imperfecta 
B)  Osteogenesis imperfecta 
C)  Hypohidrotic ectodermal dysplasia 
D)  Dentin dysplasia 
A)  Amelogenesis imperfecta 
B)  Osteogenesis imperfecta 
C)  Hypohidrotic ectodermal dysplasia 
D)  Dentin dysplasia

Question 12

A patient with Papillon-Lefèvre syndrome displays severe periodontal disease until the last tooth has been exfoliated. The skin manifestations of hyperkeratosis remain present for the life of the patient.

Accepted Answer

A)  Both statements are true. 
B)  Both statements are false. 
C)  The first statement is true; the second statement is false. 
D)  The first statement is false; the second statement is true. 
A)  Both statements are true. 
B)  Both statements are false. 
C)  The first statement is true; the second statement is false. 
D)  The first statement is false; the second statement is true.

Question 13

Ribonucleic acid (RNA) contains uracil rather than the base _____ found in DNA.

Accepted Answer

A)  adenine 
B)  guanine 
C)  cytosine 
D)  thymine 
A)  adenine 
B)  guanine 
C)  cytosine 
D)  thymine

Question 14

The _____ type of amelogenesis imperfecta is characterized by tooth enamel that does not develop to a normal thickness because of failure of the ameloblasts to lay down enamel matrix properly.

Accepted Answer

A)  hypoplastic 
B)  hypocalcified 
C)  hypomaturation 
D)  hypoplastic-hypomaturation 
A)  hypoplastic 
B)  hypocalcified 
C)  hypomaturation 
D)  hypoplastic-hypomaturation

Question 15

Which syndrome is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Accepted Answer

A)  Osler-Rendu-Parkes Weber syndrome 
B)  Van der Woude syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome 
A)  Osler-Rendu-Parkes Weber syndrome 
B)  Van der Woude syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome

Question 16

Blood group _____ is an example of gene codominance.

Accepted Answer

A)  O 
B)  A 
C)  B 
D)  AB 
A)  O 
B)  A 
C)  B 
D)  AB

Question 17

Points of contact between the chromatid of one chromosome and the chromatid of the other chromosome of a pair, where crossing over and exchange of chromosome segments occur are termed

Accepted Answer

A)  first meiosis. 
B)  second meiosis. 
C)  chiasmata. 
D)  interpolation. 
A)  first meiosis. 
B)  second meiosis. 
C)  chiasmata. 
D)  interpolation.

Question 18

Cherubism

Accepted Answer

A)  is inherited as an autosomal-dominant disease with marked penetrance in females and variable expressivity and incomplete penetrance in males. 
B)  most frequently involves the maxilla. 
C)  is characterized by a unilateral facial deformity. 
D)  reveals a typical "soap-bubble" or multilocular appearance on radiographic images. 
A)  is inherited as an autosomal-dominant disease with marked penetrance in females and variable expressivity and incomplete penetrance in males. 
B)  most frequently involves the maxilla. 
C)  is characterized by a unilateral facial deformity. 
D)  reveals a typical "soap-bubble" or multilocular appearance on radiographic images.

Question 19

The correct order for the stages of mitosis is

Accepted Answer

A)  prophase, anaphase, metaphase, telophase. 
B)  prophase, metaphase, anaphase, telophase. 
C)  prophase, metaphase, telophase, anaphase. 
D)  metaphase, prophase, telophase, anaphase. 
A)  prophase, anaphase, metaphase, telophase. 
B)  prophase, metaphase, anaphase, telophase. 
C)  prophase, metaphase, telophase, anaphase. 
D)  metaphase, prophase, telophase, anaphase.

Question 20

Each statement about chromosomes is true except one. Which one is the exception?

Accepted Answer

A)  Chromosomes are located in the nucleus of the cell. 
B)  Hereditary units called genes are found on chromosomes. 
C)  Chromosomes can only be seen clearly under a microscope when the nucleus and cell are dividing. 
D)  Chromosomes contain RNA, which directs the production of amino acids, polypeptides, and proteins by the cell. 
A)  Chromosomes are located in the nucleus of the cell. 
B)  Hereditary units called genes are found on chromosomes. 
C)  Chromosomes can only be seen clearly under a microscope when the nucleus and cell are dividing. 
D)  Chromosomes contain RNA, which directs the production of amino acids, polypeptides, and proteins by the cell.

Intestinal polyps seen with Peutz-Jeghers syndrome are

A patient with _____ will have a mouth that appears fishlike, with downward sloping of the lip commissures.

__________ is characterized by very large, pyramid-shaped molars with large pulp chambers.

Frontal bossing, depressed nasal bridge, protuberant lips, and almost complete lack of scalp hair are characteristic of a person with which condition?

What age are all of the permanent teeth typically lost in a patient with Papillon-Lefèvre syndrome?

For autosomal-dominant inheritance

The gap 1, S, and gap 2 phases are part of what type of cell division?

Oral manifestations seen with a person with Down syndrome include the following except one. Which is the exception?

Chromosomes line up at the equatorial plate during the _____ stage of mitosis.

According to the Lyon hypothesis during the early period of embryonic development, the

Your patient presents with hypodontia, hypohidrosis, and nearly complete lack of sweat and sebaceous glands. Also noticeable is a lack of eyelashes and eyebrows. Which hereditary condition is present?

A patient with Papillon-Lefèvre syndrome displays severe periodontal disease until the last tooth has been exfoliated. The skin manifestations of hyperkeratosis remain present for the life of the patient.

Ribonucleic acid (RNA) contains uracil rather than the base _____ found in DNA.

The _____ type of amelogenesis imperfecta is characterized by tooth enamel that does not develop to a normal thickness because of failure of the ameloblasts to lay down enamel matrix properly.

Which syndrome is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Blood group _____ is an example of gene codominance.

Points of contact between the chromatid of one chromosome and the chromatid of the other chromosome of a pair, where crossing over and exchange of chromosome segments occur are termed

Cherubism

The correct order for the stages of mitosis is

Each statement about chromosomes is true except one. Which one is the exception?

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

Intestinal polyps seen with Peutz-Jeghers syndrome are

A patient with _____ will have a mouth that appears fishlike, with downward sloping of the lip commissures.

__________ is characterized by very large, pyramid-shaped molars with large pulp chambers.

Frontal bossing, depressed nasal bridge, protuberant lips, and almost complete lack of scalp hair are characteristic of a person with which condition?

What age are all of the permanent teeth typically lost in a patient with Papillon-Lefèvre syndrome?

For autosomal-dominant inheritance

The gap 1, S, and gap 2 phases are part of what type of cell division?

Oral manifestations seen with a person with Down syndrome include the following except one. Which is the exception?

Chromosomes line up at the equatorial plate during the _____ stage of mitosis.

According to the Lyon hypothesis during the early period of embryonic development, the

Your patient presents with hypodontia, hypohidrosis, and nearly complete lack of sweat and sebaceous glands. Also noticeable is a lack of eyelashes and eyebrows. Which hereditary condition is present?

A patient with Papillon-Lefèvre syndrome displays severe periodontal disease until the last tooth has been exfoliated. The skin manifestations of hyperkeratosis remain present for the life of the patient.

Ribonucleic acid (RNA) contains uracil rather than the base _____ found in DNA.

The _____ type of amelogenesis imperfecta is characterized by tooth enamel that does not develop to a normal thickness because of failure of the ameloblasts to lay down enamel matrix properly.

Which syndrome is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Blood group _____ is an example of gene codominance.

Points of contact between the chromatid of one chromosome and the chromatid of the other chromosome of a pair, where crossing over and exchange of chromosome segments occur are termed

Cherubism

The correct order for the stages of mitosis is

Each statement about chromosomes is true except one. Which one is the exception?

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters