Question 1

Choose the correct answer from the list below. Not all of the answers will be used.
-A tightly bound cofactor might be called a(n) ____________.

Accepted Answer

A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria 
A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria

Question 2

The total change of free energy in a reaction depends on __________________ and __________________.

Accepted Answer

the substr

Question 3

What is the common strategy by which catalysis occurs?

Accepted Answer

A)  increasing the probability of product formation 
B)  shifting the reaction equilibrium 
C)  stabilization of transition state 
D)  All of the above. 
E)  None of the above. 
A)  increasing the probability of product formation 
B)  shifting the reaction equilibrium 
C)  stabilization of transition state 
D)  All of the above. 
E)  None of the above.

Question 4

Choose the correct answer from the list below. Not all of the answers will be used.
-An endergonic reaction requires an input of ____________ to proceed.

Accepted Answer

A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria 
A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria

Question 5

An enzyme will specifically bind its substrate because of:

Accepted Answer

A)  a tight lock-and-key binding mechanism. 
B)  a high number of hydrophobic amino acids in the center of the protein. 
C)  a large number of weak interactions at the active site. 
D)  additional nonprotein cofactors. 
E)  None of the above. 
A)  a tight lock-and-key binding mechanism. 
B)  a high number of hydrophobic amino acids in the center of the protein. 
C)  a large number of weak interactions at the active site. 
D)  additional nonprotein cofactors. 
E)  None of the above.

Question 6

Choose the correct answer from the list below. Not all of the answers will be used.
-Which model is most appropriate to explain an enzyme binding to its substrate?

Accepted Answer

A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria 
A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria

Question 7

Choose the correct answer from the list below. Not all of the answers will be used.
-A reaction that is exergonic will be ____________.

Accepted Answer

A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria 
A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria

Question 8

A reaction can occur spontaneously only if ΔG is __________________.

Accepted Answer

The answer of A reaction can occur spontaneously only if...

Question 9

Which of the following statements is most correct?

Accepted Answer

A)  Riboflavin is a coenzyme. 
B)  Flavin adenine dinucleotide is a vitamin. 
C)  Succiniate dehydrogenase is a coenzyme. 
D)  Flavin adenine dinucleotide is a coenzyme. 
A)  Riboflavin is a coenzyme. 
B)  Flavin adenine dinucleotide is a vitamin. 
C)  Succiniate dehydrogenase is a coenzyme. 
D)  Flavin adenine dinucleotide is a coenzyme.

Question 10

Choose the correct answer from the list below. Not all of the answers will be used.
-____________: The site on the enzyme where the reaction occurs.

Accepted Answer

A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria 
A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria

Question 11

An enzyme which loosely binds substrate will have a __________________ level of specificity.

Accepted Answer

The answer of An enzyme which loosely binds substrate will...

Question 12

How is the substrate bound to the active site?

Accepted Answer

The active site is a small part of the t

Question 13

Choose the correct answer from the list below. Not all of the answers will be used.
-Enzymes will decrease the energy of activation but do not change the ____________ of a chemical reaction.

Accepted Answer

A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria 
A) apoenzymes 
B) hydrolyases 
C) active site 
D) transition state 
E) spontaneous
F)induced fit
G)energy
H)prosthetic group
I)lock and key
J)substrate(s)
K)oxidoreductases
L)equilibria

Question 14

Why does this not happen in living organisms?

Accepted Answer

In a cell, the product may be

Question 15

Competitive inhibitors which mimic the substrate while in the transition state are called __________________ inhibitors.

Accepted Answer

transition

Question 16

What would be the most likely outcome of enzyme function?

Accepted Answer

The enzyme, after one round of reaction,

Question 17

The Gibbs free energy of activation is:

Accepted Answer

A)  the difference between the substrate and the transition state. 
B)  the difference between the substrate and the product. 
C)  the difference between the product and the transition state. 
D)  All of the above. 
E)  None of the above. 
A)  the difference between the substrate and the transition state. 
B)  the difference between the substrate and the product. 
C)  the difference between the product and the transition state. 
D)  All of the above. 
E)  None of the above.

Question 18

At equilibrium, the Gibbs free energy is:

Accepted Answer

A)  a positive value. 
B)  neutral. 
C)  a negative value. 
D)  zero. 
E)  one. 
A)  a positive value. 
B)  neutral. 
C)  a negative value. 
D)  zero. 
E)  one.

Question 19

The free energy of activation is:

Accepted Answer

A)  the amount of chemical energy available in the transition state. 
B)  the difference in free energy between the substrate and the product. 
C)  the free energy gained by adding a catalyst. 
D)  the difference in free energy between the transition state and the substrate. 
E)  All of the above. 
A)  the amount of chemical energy available in the transition state. 
B)  the difference in free energy between the substrate and the product. 
C)  the free energy gained by adding a catalyst. 
D)  the difference in free energy between the transition state and the substrate. 
E)  All of the above.

Question 20

The difference between the standard-state free energy, ΔG°, and the biochemical standard-state free energy is that ΔG°′ refers to the standard free-energy change at __________________.

Accepted Answer

The answer of The difference between the standard-state free energy,...

Exam 6: Basic Concepts of Enzyme Action

Choose the correct answer from the list below. Not all of the answers will be used. -A tightly bound cofactor might be called a(n) ____________.

The total change of free energy in a reaction depends on __________________ and __________________.

What is the common strategy by which catalysis occurs?

Choose the correct answer from the list below. Not all of the answers will be used. -An endergonic reaction requires an input of ____________ to proceed.

An enzyme will specifically bind its substrate because of:

Choose the correct answer from the list below. Not all of the answers will be used. -Which model is most appropriate to explain an enzyme binding to its substrate?

Choose the correct answer from the list below. Not all of the answers will be used. -A reaction that is exergonic will be ____________.

A reaction can occur spontaneously only if ΔG is __________________.

Which of the following statements is most correct?

Choose the correct answer from the list below. Not all of the answers will be used. -____________: The site on the enzyme where the reaction occurs.

An enzyme which loosely binds substrate will have a __________________ level of specificity.

How is the substrate bound to the active site?

Choose the correct answer from the list below. Not all of the answers will be used. -Enzymes will decrease the energy of activation but do not change the ____________ of a chemical reaction.

Why does this not happen in living organisms?

Competitive inhibitors which mimic the substrate while in the transition state are called __________________ inhibitors.

What would be the most likely outcome of enzyme function?

The Gibbs free energy of activation is:

At equilibrium, the Gibbs free energy is:

The free energy of activation is:

The difference between the standard-state free energy, ΔG°, and the biochemical standard-state free energy is that ΔG°′ refers to the standard free-energy change at __________________.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant DNA Techniques

Filters

The total change of free energy in a reaction depends on and .