Question 1

Hydroxylation of cholesterol by cytochrome P450 requires:

Accepted Answer

A)  NADPH. 
B)  activated O2. 
C)  PLP. 
D)  A and B. 
E)  A and C. 
A)  NADPH. 
B)  activated O2. 
C)  PLP. 
D)  A and B. 
E)  A and C.

Question 2

Vitamin D3 is converted into ___________________, which is an active hormone that functions as a transcription factor.

Accepted Answer

calcitriol

Question 3

_________________ is composed of a fatty acid linked to sphingosine via an amide bond.

Accepted Answer

The answer of _________________ is composed of a fatty acid...

Question 4

Which of the following is the common precursor for both the phosphatidyl inositols and triacylglycerols?

Accepted Answer

A)  diacylglycerol 
B)  inosinic acid 
C)  phosphatidate 
D)  CDP-diacylglycerol 
E)  None of the above. 
A)  diacylglycerol 
B)  inosinic acid 
C)  phosphatidate 
D)  CDP-diacylglycerol 
E)  None of the above.

Question 5

The starting materials necessary to synthesize sphingosine are:

Accepted Answer

A)  palmitoyl CoA and serine. 
B)  acetyl CoA and glycine. 
C)  palmitoyl CoA and aspartate. 
D)  acetyl CoA and glutamine. 
E)  None of the above. 
A)  palmitoyl CoA and serine. 
B)  acetyl CoA and glycine. 
C)  palmitoyl CoA and aspartate. 
D)  acetyl CoA and glutamine. 
E)  None of the above.

Question 6

Why is phosphatidyl serine considered a class of molecules, and not one type?

Accepted Answer

Because varying fatty acids gr

Question 7

What are the causes and symptoms of familial hypercholesterolemia?

Accepted Answer

The hallmark of this genetic disease is

Question 8

What is the role of CTP in the synthesis of a phospholipid?

Accepted Answer

In the de novo synthesis, the CTP is use

Question 9

Phosphatidate is formed from:

Accepted Answer

A)  glycerol 3-phosphate and two fatty acyl CoA's. 
B)  glycerol and two free fatty acids. 
C)  pyruvate and triacylglycerol. 
D)  glycerol and two fatty acyl CoA's. 
E)  None of the above. 
A)  glycerol 3-phosphate and two fatty acyl CoA's. 
B)  glycerol and two free fatty acids. 
C)  pyruvate and triacylglycerol. 
D)  glycerol and two fatty acyl CoA's. 
E)  None of the above.

Question 10

What are the steps in LDL uptake into cells?

Accepted Answer

The LDL contains apolipoprotein B-100, w

Question 11

List the types of lipoprotein particles and give the primary physiological role of the lipoprotein.

Accepted Answer

See Table 29.1.
Lipoprotein Physiologica

Question 12

Choose the correct answer from the list below. Not all of the answers will be used.
-The reduction of the metabolite _______________ supplies glycerol 3-phosphate for acylglycerol synthesis.

Accepted Answer

A) liver 
B) receptor-mediated endocytosis 
C) phosphatidyl ethanolamine 
D) muscle 
E) lipoprotein particles
F)dihydroxyacetone phosphate
G)vitamin D
H)pregnenolone
I)glycocholate
J)acetyl CoA
K)vitamin A
L)sphingomyelin 
A) liver 
B) receptor-mediated endocytosis 
C) phosphatidyl ethanolamine 
D) muscle 
E) lipoprotein particles
F)dihydroxyacetone phosphate
G)vitamin D
H)pregnenolone
I)glycocholate
J)acetyl CoA
K)vitamin A
L)sphingomyelin

Question 13

The highest concentration of sphingolipids is found in the:

Accepted Answer

A)  central nervous system. 
B)  lymph system. 
C)  serum. 
D)  All of the above. 
E)  None of the above. 
A)  central nervous system. 
B)  lymph system. 
C)  serum. 
D)  All of the above. 
E)  None of the above.

Question 14

Choose the correct answer from the list below. Not all of the answers will be used.
-In mammals, the _______________ is the major site of triacylglycerol synthesis.

Accepted Answer

A) liver 
B) receptor-mediated endocytosis 
C) phosphatidyl ethanolamine 
D) muscle 
E) lipoprotein particles
F)dihydroxyacetone phosphate
G)vitamin D
H)pregnenolone
I)glycocholate
J)acetyl CoA
K)vitamin A
L)sphingomyelin 
A) liver 
B) receptor-mediated endocytosis 
C) phosphatidyl ethanolamine 
D) muscle 
E) lipoprotein particles
F)dihydroxyacetone phosphate
G)vitamin D
H)pregnenolone
I)glycocholate
J)acetyl CoA
K)vitamin A
L)sphingomyelin

Question 15

In mammalian cells, phosphatidate is synthesized in the outer mitrochondrial membrane and the ___________________.

Accepted Answer

endoplasmi

Question 16

What are bile salts?

Accepted Answer

Bile salts are amphiphilic derivatives o

Question 17

The LDL receptors on the plasma membrane are localized in coated pits that contain the receptors of which of the following proteins?

Accepted Answer

A)  clathrin 
B)  lipoprotein A 
C)  adrenodoxin 
D)  HMG-CoA reductase 
E)  sterol regulatory element binding protein (SREBP) 
A)  clathrin 
B)  lipoprotein A 
C)  adrenodoxin 
D)  HMG-CoA reductase 
E)  sterol regulatory element binding protein (SREBP)

Question 18

Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is the primary bile salt.

Accepted Answer

A) liver 
B) receptor-mediated endocytosis 
C) phosphatidyl ethanolamine 
D) muscle 
E) lipoprotein particles
F)dihydroxyacetone phosphate
G)vitamin D
H)pregnenolone
I)glycocholate
J)acetyl CoA
K)vitamin A
L)sphingomyelin 
A) liver 
B) receptor-mediated endocytosis 
C) phosphatidyl ethanolamine 
D) muscle 
E) lipoprotein particles
F)dihydroxyacetone phosphate
G)vitamin D
H)pregnenolone
I)glycocholate
J)acetyl CoA
K)vitamin A
L)sphingomyelin

Question 19

What is the role of phosphatidyl choline in the synthesis of sphingomyelin?

Accepted Answer

Phosphatidyl choline supplies

Question 20

Describe the various ways that 3-hydroxy-3-methylglutaryl CoA reductase is regulated, including both gene expression and enzyme regulation.

Accepted Answer

There are several mechanisms. (1) Synthe

Exam 29: Lipid Synthesis

Hydroxylation of cholesterol by cytochrome P450 requires:

Vitamin D3 is converted into ___________________, which is an active hormone that functions as a transcription factor.

_________________ is composed of a fatty acid linked to sphingosine via an amide bond.

Which of the following is the common precursor for both the phosphatidyl inositols and triacylglycerols?

The starting materials necessary to synthesize sphingosine are:

Why is phosphatidyl serine considered a class of molecules, and not one type?

What are the causes and symptoms of familial hypercholesterolemia?

What is the role of CTP in the synthesis of a phospholipid?

Phosphatidate is formed from:

What are the steps in LDL uptake into cells?

List the types of lipoprotein particles and give the primary physiological role of the lipoprotein.

Choose the correct answer from the list below. Not all of the answers will be used. -The reduction of the metabolite _______________ supplies glycerol 3-phosphate for acylglycerol synthesis.

The highest concentration of sphingolipids is found in the:

Choose the correct answer from the list below. Not all of the answers will be used. -In mammals, the _______________ is the major site of triacylglycerol synthesis.

In mammalian cells, phosphatidate is synthesized in the outer mitrochondrial membrane and the ___________________.

What are bile salts?

The LDL receptors on the plasma membrane are localized in coated pits that contain the receptors of which of the following proteins?

Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is the primary bile salt.

What is the role of phosphatidyl choline in the synthesis of sphingomyelin?

Describe the various ways that 3-hydroxy-3-methylglutaryl CoA reductase is regulated, including both gene expression and enzyme regulation.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant DNA Techniques

Filters