Question 1

How are breaks in DNA sealed that were formed during nucleotide-excision repair?

Accepted Answer

DNA ligase is the enzyme that seals the

Question 2

How are breaks in DNA sealed that were formed during nucleotide-excision repair?

Accepted Answer

DNA ligase is the enzyme that seals the

Question 3

Describe the difficulties in dealing with halts in DNA replication.

Accepted Answer

Replication pauses occur with

Question 4

Describe the difficulties in dealing with halts in DNA replication.

Accepted Answer

Replication pauses occur with

Question 5

Hydroxyl radicals cause DNA damage by ___________________.

Accepted Answer

reacting w

Question 6

Choose the correct answer from the list below. Not all of the answers will be used.
-The enzyme that uses light energy to form an excited state to cleave the dimer into individual bases is _______________.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 7

Aflatoxin B1 is an example of a(n):

Accepted Answer

A)  intercalating chemical. 
B)  alkylating agent. 
C)  base analog. 
D)  All of the above. 
E)  None of the above. 
A)  intercalating chemical. 
B)  alkylating agent. 
C)  base analog. 
D)  All of the above. 
E)  None of the above.

Question 8

Proteins that contain a string of glutamines are likely to be involved in ___________________ disease.

Accepted Answer

The answer of Proteins that contain a string of glutamines...

Question 9

Exposure to aflatoxin B1 can lead to:

Accepted Answer

A)  the expansion of repeats of three nucleotides. 
B)  DNA damage by alkylation. 
C)  the defective repair of DNA. 
D)  the recombination of DNA. 
E)  None of the above. 
A)  the expansion of repeats of three nucleotides. 
B)  DNA damage by alkylation. 
C)  the defective repair of DNA. 
D)  the recombination of DNA. 
E)  None of the above.

Question 10

What is DNA adduct and how is it formed?

Accepted Answer

DNA adduct is a general term f

Question 11

Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are involved in joining DNA molecules together.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 12

Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ chemically changes the nature of a base in DNA.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 13

Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are often found to cause alternative structures in DNA replication.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 14

The human genetic skin disease that is caused by a mutation in components of the human nucleotide-excision-repair pathway is called ___________________.

Accepted Answer

xeroderma

Question 15

___________________ is the enzyme that converts polycyclic aromatic hydrocarbons into a reactive epoxide that alkylates the N-7 of guanine.

Accepted Answer

The answer of ___________________ is the enzyme that converts polycyclic...

Question 16

The process whereby two daughter molecules of DNA are formed by the exchange of genetic material between two parent molecules is known as:

Accepted Answer

A)  chemical modification. 
B)  recombination. 
C)  alkylation. 
D)  dimerization. 
E)  None of the above. 
A)  chemical modification. 
B)  recombination. 
C)  alkylation. 
D)  dimerization. 
E)  None of the above.

Question 17

How do double-strand breaks occur during replication?

Accepted Answer

Double-strand breaks occur when the poly

Question 18

What are DNA adduct and how are they formed?

Accepted Answer

"DNA adduct" is a general term

Question 19

Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is an enzyme that cleaves a glycosidic bond to release a damaged base.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 20

In E. coli, mismatch repair involves

Accepted Answer

A)  recognition of mismatched pair by MutS. 
B)  removal of a mismatched nucleotide by DNA polymerase III. 
C)  cleavage of the backbone by MutH. 
D)  A and C 
E)  A, B, and C. 
A)  recognition of mismatched pair by MutS. 
B)  removal of a mismatched nucleotide by DNA polymerase III. 
C)  cleavage of the backbone by MutH. 
D)  A and C 
E)  A, B, and C.

Exam 35: DNA Repair and Recombination

How are breaks in DNA sealed that were formed during nucleotide-excision repair?

How are breaks in DNA sealed that were formed during nucleotide-excision repair?

Describe the difficulties in dealing with halts in DNA replication.

Describe the difficulties in dealing with halts in DNA replication.

Hydroxyl radicals cause DNA damage by ___________________.

Choose the correct answer from the list below. Not all of the answers will be used. -The enzyme that uses light energy to form an excited state to cleave the dimer into individual bases is _______________.

Aflatoxin B1 is an example of a(n):

Proteins that contain a string of glutamines are likely to be involved in ___________________ disease.

Exposure to aflatoxin B1 can lead to:

What is DNA adduct and how is it formed?

Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are involved in joining DNA molecules together.

Choose the correct answer from the list below. Not all of the answers will be used. -_______________ chemically changes the nature of a base in DNA.

Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are often found to cause alternative structures in DNA replication.

The human genetic skin disease that is caused by a mutation in components of the human nucleotide-excision-repair pathway is called ___________________.

___________________ is the enzyme that converts polycyclic aromatic hydrocarbons into a reactive epoxide that alkylates the N-7 of guanine.

The process whereby two daughter molecules of DNA are formed by the exchange of genetic material between two parent molecules is known as:

How do double-strand breaks occur during replication?

What are DNA adduct and how are they formed?

Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is an enzyme that cleaves a glycosidic bond to release a damaged base.

In E. coli, mismatch repair involves

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant DNA Techniques

Filters

Aflatoxin B₁ is an example of a(n):