Question 1

The reaction catalyzed by __________________ transfers UDP-glucose to the hydroxyl of an existing glycogen core.

Accepted Answer

A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease 
A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease

Question 2

The complete oxidation of a glucose residue from glycogen produces ________________ ATP.

Accepted Answer

The answer of The complete oxidation of a glucose residue...

Question 3

_______________ is the glycogen storage disease in which the defective enzyme is glucose 6-phosphatase.

Accepted Answer

A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease 
A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease

Question 4

In general, phospho- forms of glycogen synthase lead to ________________ levels of glycogen.

Accepted Answer

The answer of In general, phospho- forms of glycogen synthase...

Question 5

An incorrect, tight binding of PP1 to glycogen synthase would result in:

Accepted Answer

A)  a hyperactive glycogen synthase. 
B)  hyper-glycogen levels. 
C)  increased insulin action. 
D)  high blood glucose. 
E)  activated glycogen synthase. 
A)  a hyperactive glycogen synthase. 
B)  hyper-glycogen levels. 
C)  increased insulin action. 
D)  high blood glucose. 
E)  activated glycogen synthase.

Question 6

The enzyme that begins the kinase cascade, activating glycogen degradation, is:

Accepted Answer

A)  glycogen synthase. 
B)  phosphorylase kinase. 
C)  PKC. 
D)  PKA. 
E)  tyrosine kinase. 
A)  glycogen synthase. 
B)  phosphorylase kinase. 
C)  PKC. 
D)  PKA. 
E)  tyrosine kinase.

Question 7

There is a high __________________-to-insulin ratio in diabetes.

Accepted Answer

The answer of There is a high __________________-to-insulin ratio in...

Question 8

Which is the true glucose-level sensor in the cell?

Accepted Answer

A)  insulin 
B)  phosphorylase a 
C)  glucagon 
D)  glycogen synthase 
E)  protein phosphatase 1 
A)  insulin 
B)  phosphorylase a 
C)  glucagon 
D)  glycogen synthase 
E)  protein phosphatase 1

Question 9

Explain how the formation of UDP-glucose from glucose 1-phosphate and UTP is essentially reversible.

Accepted Answer

The hydrolysis of pyrophosphate (PPi) to

Question 10

Which of the following occur after a carbohydrate-rich meal?

Accepted Answer

A)  Blood-glucose levels increase, leading to glycogen storage in the liver. 
B)  Blood-glucose levels increase, leading to glycogen storage in the muscle. 
C)  Glycogen storage in the muscle shuts down. 
D)  All of the above. 
E)  None of the above. 
A)  Blood-glucose levels increase, leading to glycogen storage in the liver. 
B)  Blood-glucose levels increase, leading to glycogen storage in the muscle. 
C)  Glycogen storage in the muscle shuts down. 
D)  All of the above. 
E)  None of the above.

Question 11

The __________________ creates a 1,6-glycosidic bond.

Accepted Answer

A)  branching enzyme 
B)  glucose transferase 
C)  glycogen isomerase 
D)  glycogen synthase 
E)  None of the above. 
A)  branching enzyme 
B)  glucose transferase 
C)  glycogen isomerase 
D)  glycogen synthase 
E)  None of the above.

Question 12

Explain why Type I diabetes is often called "fasting in the sea of plenty."

Accepted Answer

The muscle cell is not able to transport

Question 13

After exercise, muscle cell glycogen metabolism is regulated by:

Accepted Answer

A)  insulin. 
B)  phosphorylase a. 
C)  glucagon. 
D)  glycogen synthase. 
E)  protein phosphatase 1. 
A)  insulin. 
B)  phosphorylase a. 
C)  glucagon. 
D)  glycogen synthase. 
E)  protein phosphatase 1.

Question 14

Glycogen synthase is converted into the active form by the action of __________________.

Accepted Answer

protein ph

Question 15

The activated glucose donor of glycogen synthesis is:

Accepted Answer

A)  glucose 1-phosphate. 
B)  glucose. 
C)  ATP. 
D)  UTP. 
E)  None of the above. 
A)  glucose 1-phosphate. 
B)  glucose. 
C)  ATP. 
D)  UTP. 
E)  None of the above.

Question 16

How are new glucosyl units added to a growing glycogen molecule?

Accepted Answer

Glucosyl units are added to th

Question 17

Explain how the liver responds to muscle challenges in insulin-dependent diabetes.

Accepted Answer

The liver primarily

Question 18

__________________ is is a primer that polymerizes the first few glucose molecules.

Accepted Answer

A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease 
A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease

Question 19

Give the reaction catalyzed by UDP-glucose pyrophosphorylase.

Accepted Answer

Glucose 1-

Question 20

_______________ is the key regulatory enzyme in glycogen synthesis.

Accepted Answer

A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease 
A) UDP-glucose 
B) nonreducing 
C) synthesis 
D) glucose 
E) glycogenin
F)Von Gierke disease
G)glycogen synthase
H)UTP-glucose
I)protein phosphatase 1 (PP1)
J)PPi
K)glycogen phosphate
L)McArdle disease

Exam 25: Glycogen Synthesis

The reaction catalyzed by __________________ transfers UDP-glucose to the hydroxyl of an existing glycogen core.

The complete oxidation of a glucose residue from glycogen produces ________________ ATP.

_______________ is the glycogen storage disease in which the defective enzyme is glucose 6-phosphatase.

In general, phospho- forms of glycogen synthase lead to ________________ levels of glycogen.

An incorrect, tight binding of PP1 to glycogen synthase would result in:

The enzyme that begins the kinase cascade, activating glycogen degradation, is:

There is a high __________________-to-insulin ratio in diabetes.

Which is the true glucose-level sensor in the cell?

Explain how the formation of UDP-glucose from glucose 1-phosphate and UTP is essentially reversible.

Which of the following occur after a carbohydrate-rich meal?

The __________________ creates a 1,6-glycosidic bond.

Explain why Type I diabetes is often called "fasting in the sea of plenty."

After exercise, muscle cell glycogen metabolism is regulated by:

Glycogen synthase is converted into the active form by the action of __________________.

The activated glucose donor of glycogen synthesis is:

How are new glucosyl units added to a growing glycogen molecule?

Explain how the liver responds to muscle challenges in insulin-dependent diabetes.

__________________ is is a primer that polymerizes the first few glucose molecules.

Give the reaction catalyzed by UDP-glucose pyrophosphorylase.

_______________ is the key regulatory enzyme in glycogen synthesis.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant Dna Techniques

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