Question 1

How does a nucleotide differ from a nucleoside?

Accepted Answer

A)  Nucleosides are found in DNA, whereas nucleotides are found in RNA. 
B)  Purines are only found in nucleotides. 
C)  Nucleosides contain only deoxyribose sugars. 
D)  A nucleotide is a nucleoside with a phosphate ester linked to the sugar . 
E)  None of the above. 
A)  Nucleosides are found in DNA, whereas nucleotides are found in RNA. 
B)  Purines are only found in nucleotides. 
C)  Nucleosides contain only deoxyribose sugars. 
D)  A nucleotide is a nucleoside with a phosphate ester linked to the sugar . 
E)  None of the above.

Question 2

Compare and contrast the three forms of DNA with respect to handedness and hydration state.

Accepted Answer

The Watson and Crick model of DNA is kno

Question 3

After two generations of replication in the Meselson and Stahl experiment, what was the composition of the two bands?

Accepted Answer

A)  One band was all 14N and one band was all 15N. 
B)  One band was all 14N and one band was half 14N and half 15N. 
C)  One band was all 15N and one band was half 14N and half 15N. 
D)  One band was all 14N and one band was one quarter 14N and three quarters 15N. 
E)  One band was all 15N and one band was one quarter 14N and three quarters 15N. 
A)  One band was all 14N and one band was all 15N. 
B)  One band was all 14N and one band was half 14N and half 15N. 
C)  One band was all 15N and one band was half 14N and half 15N. 
D)  One band was all 14N and one band was one quarter 14N and three quarters 15N. 
E)  One band was all 15N and one band was one quarter 14N and three quarters 15N.

Question 4

The temperature at which half of the DNA helical structure is lost is called the:

Accepted Answer

A)  denaturation temperature. 
B)  Tm. 
C)  annealing temperature. 
D)  dehybridization temperaure. 
E)  Replication temperature. 
A)  denaturation temperature. 
B)  Tm. 
C)  annealing temperature. 
D)  dehybridization temperaure. 
E)  Replication temperature.

Question 5

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-H2A, H2B, H3, and H4 are all major classes of _______________.

Accepted Answer

A) supercoiling 
B) DNA 
C) 5` → 3` 
D) circular 
E) stem loop
F)B-DNA
G)retroviruses
H)exon
I)Erwin Chargaff
J)histones
K)RNA
L)Rosalind Franklin
M)A-DNA
N)3` → 5` 
A) supercoiling 
B) DNA 
C) 5` → 3` 
D) circular 
E) stem loop
F)B-DNA
G)retroviruses
H)exon
I)Erwin Chargaff
J)histones
K)RNA
L)Rosalind Franklin
M)A-DNA
N)3` → 5`

Question 6

The difference in RNA bases compared to DNA bases is:

Accepted Answer

A)  RNA contains A instead of T. 
B)  RNA contains U instead of G. 
C)  RNA contains U instead of T. 
D)  RNA contains A instead of U. 
E)  None of the above. 
A)  RNA contains A instead of T. 
B)  RNA contains U instead of G. 
C)  RNA contains U instead of T. 
D)  RNA contains A instead of U. 
E)  None of the above.

Question 7

Draw two nucleotides in DNA, showing the linkage between the sugars.

Accepted Answer

The 3` oxygen of one nucleotide is linke

Question 8

5` dAMP refers to __________________.

Accepted Answer

deoxyadeno

Question 9

The feature(s) of DNA deduced by Watson and Crick include:

Accepted Answer

A)  two antiparallel polynucleotide chains coiled in a helix around a common axis. 
B)  that the pyrimidine and purine bases lie on the inside of the helix. 
C)  that the bases are nearly perpendicular to the axis. 
D)  All of the above. 
E)  None of the above. 
A)  two antiparallel polynucleotide chains coiled in a helix around a common axis. 
B)  that the pyrimidine and purine bases lie on the inside of the helix. 
C)  that the bases are nearly perpendicular to the axis. 
D)  All of the above. 
E)  None of the above.

Question 10

The distribution of parental atoms in newly synthesized DNA is called __________________ replication.

Accepted Answer

The answer of The distribution of parental atoms in newly...

Question 11

Briefly describe the Meselson and Stahl experiment that indicated that DNA replication is semiconservative

Accepted Answer

Meselson and Stahl grew bacteria in the

Question 12

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-DNA can exist in both linear and _______________ forms.

Accepted Answer

A) supercoiling 
B) DNA 
C) 5` → 3` 
D) circular 
E) stem loop
F)B-DNA
G)retroviruses
H)exon
I)Erwin Chargaff
J)histones
K)RNA
L)Rosalind Franklin
M)A-DNA
N)3` → 5` 
A) supercoiling 
B) DNA 
C) 5` → 3` 
D) circular 
E) stem loop
F)B-DNA
G)retroviruses
H)exon
I)Erwin Chargaff
J)histones
K)RNA
L)Rosalind Franklin
M)A-DNA
N)3` → 5`

Question 13

A nitrogen containing an aromatic base attached to a ribose is a __________________.

Accepted Answer

The answer of A nitrogen containing an aromatic base attached...

Question 14

What is the approximate error rate in DNA replication?

Accepted Answer

A)  1 x10−8 
B)  1 x 10−6 
C)  1 x 10−15 
D)  1 x 10−10 
E)  None of the above. 
A)  1 x10−8 
B)  1 x 10−6 
C)  1 x 10−15 
D)  1 x 10−10 
E)  None of the above.

Question 15

Why is there a major and a minor groove in DNA?

Accepted Answer

The major and minor grooves arise becaus

Question 16

The anticancer drug cisplatin disrupts:

Accepted Answer

A)  histone binding to DNA. 
B)  supercoiling of DNA. 
C)  chromatin-DNA binding. 
D)  replication and transcription. 
E)  None of the above. 
A)  histone binding to DNA. 
B)  supercoiling of DNA. 
C)  chromatin-DNA binding. 
D)  replication and transcription. 
E)  None of the above.

Question 17

The __________________ effect stabilizes the structure of DNA, resulting in more polar surfaces being exposed to the aqueous media.

Accepted Answer

The answer of The __________________ effect stabilizes the structure of...

Question 18

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-The base sequence, as written by convention, is in the _______________ direction.

Accepted Answer

A) supercoiling 
B) DNA 
C) 5` → 3` 
D) circular 
E) stem loop
F)B-DNA
G)retroviruses
H)exon
I)Erwin Chargaff
J)histones
K)RNA
L)Rosalind Franklin
M)A-DNA
N)3` → 5` 
A) supercoiling 
B) DNA 
C) 5` → 3` 
D) circular 
E) stem loop
F)B-DNA
G)retroviruses
H)exon
I)Erwin Chargaff
J)histones
K)RNA
L)Rosalind Franklin
M)A-DNA
N)3` → 5`

Question 19

What role does a nucleosome play in DNA structure?

Accepted Answer

A nucleosome consists of approximately 2

Question 20

RNA:

Accepted Answer

A)  is oxygenated on the 2` of ribose. 
B)  can form non-Watson-Crick base pairings. 
C)  uses metals to stabilize folding. 
D)  may form triplet base pairings. 
E)  All of the above. 
A)  is oxygenated on the 2` of ribose. 
B)  can form non-Watson-Crick base pairings. 
C)  uses metals to stabilize folding. 
D)  may form triplet base pairings. 
E)  All of the above.

Exam 33: The Structure of Informational Macromolecules: Dna and Rna

How does a nucleotide differ from a nucleoside?

Compare and contrast the three forms of DNA with respect to handedness and hydration state.

After two generations of replication in the Meselson and Stahl experiment, what was the composition of the two bands?

The temperature at which half of the DNA helical structure is lost is called the:

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -H2A, H2B, H3, and H4 are all major classes of _______________.

The difference in RNA bases compared to DNA bases is:

Draw two nucleotides in DNA, showing the linkage between the sugars.

5` dAMP refers to __________________.

The feature(s) of DNA deduced by Watson and Crick include:

The distribution of parental atoms in newly synthesized DNA is called __________________ replication.

Briefly describe the Meselson and Stahl experiment that indicated that DNA replication is semiconservative

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -DNA can exist in both linear and _______________ forms.

A nitrogen containing an aromatic base attached to a ribose is a __________________.

What is the approximate error rate in DNA replication?

Why is there a major and a minor groove in DNA?

The anticancer drug cisplatin disrupts:

The __________________ effect stabilizes the structure of DNA, resulting in more polar surfaces being exposed to the aqueous media.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -The base sequence, as written by convention, is in the _______________ direction.

What role does a nucleosome play in DNA structure?

RNA:

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant Dna Techniques

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