Question 1

Aflatoxin B1 is an example of a(n):

Accepted Answer

A)  intercalating chemical. 
B)  alkylating agent. 
C)  base analog. 
D)  All of the above. 
E)  None of the above. 
A)  intercalating chemical. 
B)  alkylating agent. 
C)  base analog. 
D)  All of the above. 
E)  None of the above.

Question 2

What are DNA adduct and how are they formed?

Accepted Answer

"DNA adduct" is a general term

Question 3

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-The enzyme that uses light energy to form an excited state to cleave the dimer into individual bases is _______________.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 4

The three-strand structure involved in strand invasion is:

Accepted Answer

A)  the D-loop. 
B)  recombinase DNA. 
C)  an RNA triplet. 
D)  non-Watson-Crick pairing. 
E)  RecA 
A)  the D-loop. 
B)  recombinase DNA. 
C)  an RNA triplet. 
D)  non-Watson-Crick pairing. 
E)  RecA

Question 5

Deamination of adenine causes what kind of mutations in DNA?

Accepted Answer

The loss of NH3 forms hypoxant

Question 6

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-A(n) _______________ chemically changes the nature of a base in DNA.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 7

How do double-strand breaks occur during replication?

Accepted Answer

Double-strand breaks occur when the poly

Question 8

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are typically involved in DNA repair.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 9

Hydroxyl radicals cause DNA damage by ___________________.

Accepted Answer

reacting w

Question 10

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-An assay used to determine carcinogenic potential is the _______________ test.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 11

An important feature(s) of the Ames test is/are:

Accepted Answer

A)  the inclusion of mammalian liver enzymes. 
B)  a linear response curve. 
C)  that the bacteria used are unable to grow in the absence of arginine. 
D)  A and B. 
E)  A, B and C. 
A)  the inclusion of mammalian liver enzymes. 
B)  a linear response curve. 
C)  that the bacteria used are unable to grow in the absence of arginine. 
D)  A and B. 
E)  A, B and C.

Question 12

Give examples of types of damage to DNA that have led to the development of a variety of DNA-repair systems.

Accepted Answer

The simplest form of damage is the misin

Question 13

How are breaks in DNA sealed that were formed during nucleotide-excision repair?

Accepted Answer

DNA ligase is the enzyme that seals the

Question 14

___________________ are intermediates in recombination pathways composed of four polynucleotide chains in a cross-like structure.

Accepted Answer

The answer of ___________________ are intermediates in recombination pathways composed...

Question 15

E coli DNA polymerase III removes mismatched nucleotides from the ___________________.

Accepted Answer

The answer of E coli DNA polymerase III removes mismatched...

Question 16

Proteins that contain a string of glutamines are likely to be involved in ___________________ disease.

Accepted Answer

The answer of Proteins that contain a string of glutamines...

Question 17

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is an enzyme that cleaves a glycosidic bond to release a damaged base.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 18

_________________ is an ATPase needed for DNA repair by recombination.

Accepted Answer

A)  Polymerase III 
B)  RecA 
C)  RecB 
D)  RAD51 
E)  None of the above. 
A)  Polymerase III 
B)  RecA 
C)  RecB 
D)  RAD51 
E)  None of the above.

Question 19

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are often found to cause alternative structures in DNA replication.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 20

Exposure to aflatoxin B1 can lead to:

Accepted Answer

A)  the expansion of repeats of three nucleotides. 
B)  DNA damage by alkylation. 
C)  the defective repair of DNA. 
D)  the recombination of DNA. 
E)  None of the above. 
A)  the expansion of repeats of three nucleotides. 
B)  DNA damage by alkylation. 
C)  the defective repair of DNA. 
D)  the recombination of DNA. 
E)  None of the above.

Exam 35: DNA Repair and Recombination

Aflatoxin B1 is an example of a(n):

What are DNA adduct and how are they formed?

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -The enzyme that uses light energy to form an excited state to cleave the dimer into individual bases is _______________.

The three-strand structure involved in strand invasion is:

Deamination of adenine causes what kind of mutations in DNA?

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -A(n) _______________ chemically changes the nature of a base in DNA.

How do double-strand breaks occur during replication?

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are typically involved in DNA repair.

Hydroxyl radicals cause DNA damage by ___________________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -An assay used to determine carcinogenic potential is the _______________ test.

An important feature(s) of the Ames test is/are:

Give examples of types of damage to DNA that have led to the development of a variety of DNA-repair systems.

How are breaks in DNA sealed that were formed during nucleotide-excision repair?

___________________ are intermediates in recombination pathways composed of four polynucleotide chains in a cross-like structure.

E coli DNA polymerase III removes mismatched nucleotides from the ___________________.

Proteins that contain a string of glutamines are likely to be involved in ___________________ disease.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is an enzyme that cleaves a glycosidic bond to release a damaged base.

_________________ is an ATPase needed for DNA repair by recombination.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are often found to cause alternative structures in DNA replication.

Exposure to aflatoxin B1 can lead to:

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant Dna Techniques

Filters