Question 1

Which of the following is NOT a function of a cilium?

Accepted Answer

A) moving the cell from place to place 
B) moving fluid and particulate material past the cell 
C) a role in sensory function in monitoring the properties of extracellular fluids 
D) moving vesicles down the nerve cell axon 
E) All of these choices are functions of a cilium. 
A) moving the cell from place to place 
B) moving fluid and particulate material past the cell 
C) a role in sensory function in monitoring the properties of extracellular fluids 
D) moving vesicles down the nerve cell axon 
E) All of these choices are functions of a cilium.

Question 2

Which of the following molecules is a non-diffusible,integral protein of the plasma membrane that binds specifically to its receptor on the surface of the growth cone? This protein acts as a neuronal guidance factor.

Accepted Answer

A) ephrin 
B) netrin 
C) integrin 
D) axin 
E) guidin 
A) ephrin 
B) netrin 
C) integrin 
D) axin 
E) guidin

Question 3

The point at which the neuron axon terminus and the muscle fiber make contact is called the _________.

Accepted Answer

A) neuromuscular terminus 
B) nerve exons 
C) neural conjunctions 
D) neuromuscular junction 
E) neuromuscular conjunction 
A) neuromuscular terminus 
B) nerve exons 
C) neural conjunctions 
D) neuromuscular junction 
E) neuromuscular conjunction

Question 4

What is the direct source of energy that powers molecular motors?

Accepted Answer

A) hydrolysis of GTP 
B) hydrolysis of ATP 
C) a proton gradient 
D) a H+ gradient 
E) condensation of ATP 
A) hydrolysis of GTP 
B) hydrolysis of ATP 
C) a proton gradient 
D) a H+ gradient 
E) condensation of ATP

Question 5

The central,rod-shaped domain of an intermediate filament is flanked on each side by globular domains of variable size and sequence.What structure forms the core of the central,rod-shaped domain?

Accepted Answer

A) alpha-helix 
B) beta-pleated sheet 
C) double helix 
D) quaternary coil 
E) coiled coil 
A) alpha-helix 
B) beta-pleated sheet 
C) double helix 
D) quaternary coil 
E) coiled coil

Question 6

You inject labeled keratin subunits into cultured skin cells.What happens a few minutes later?

Accepted Answer

A) The keratin subunits remain in the cytoplasmic keratin subunit pool. 
B) Filaments become labeled at sites scattered throughout their length,rather than at their ends. 
C) Filaments become labeled at both ends simultaneously. 
D) Filaments become labeled at one end exclusively. 
E) The entire intermediate filament network is quickly labeled. 
A) The keratin subunits remain in the cytoplasmic keratin subunit pool. 
B) Filaments become labeled at sites scattered throughout their length,rather than at their ends. 
C) Filaments become labeled at both ends simultaneously. 
D) Filaments become labeled at one end exclusively. 
E) The entire intermediate filament network is quickly labeled.

Question 7

Which cytoskeletal element is found could be described as solid,thinner structures that are often organized into a branching network?

Accepted Answer

A) microfilaments 
B) microtubules 
C) intermediate filaments 
D) macrotubules 
E) minifilaments 
A) microfilaments 
B) microtubules 
C) intermediate filaments 
D) macrotubules 
E) minifilaments

Question 8

What would happen if you cultured a frog embryo just after gastrulation in the presence of colchicine?

Accepted Answer

A) The cells of the neural plate would elongate more than normal. 
B) The cells of the neural plate would elongate much less than normal or not at all. 
C) The cells of the neural plate elongate normally but do not become constricted as usually happens. 
D) The cells of the neural plate elongate normally but become more constricted than they usually do. 
E) The cells of the neural plate do not elongate and do not become constricted as they usually do. 
A) The cells of the neural plate would elongate more than normal. 
B) The cells of the neural plate would elongate much less than normal or not at all. 
C) The cells of the neural plate elongate normally but do not become constricted as usually happens. 
D) The cells of the neural plate elongate normally but become more constricted than they usually do. 
E) The cells of the neural plate do not elongate and do not become constricted as they usually do.

Question 9

The first direct measurement of a motor taking single steps was an analysis of _______ stepping using _________.

Accepted Answer

A) myosin,optical trap technology 
B) dynein,ion exchange chromatography 
C) kinesin,optical trap technology 
D) kinesin,ion exchange chromatography 
E) dynein,polyacrylamide gel electrophoresis 
A) myosin,optical trap technology 
B) dynein,ion exchange chromatography 
C) kinesin,optical trap technology 
D) kinesin,ion exchange chromatography 
E) dynein,polyacrylamide gel electrophoresis

Question 10

The deletion of the creS gene in Caulobacter crescentus results in __________.

Accepted Answer

A) cells that look like straight rods 
B) crescent-shaped cells 
C) spherical cells 
D) spiral cells 
E) cells that look like bunches of grapes 
A) cells that look like straight rods 
B) crescent-shaped cells 
C) spherical cells 
D) spiral cells 
E) cells that look like bunches of grapes

Question 11

Why are taxol,vinblastine and other drugs like them used as chemotherapy agents?

Accepted Answer

A) They preferentially kill tumor cells. 
B) They preferentially stabilize tumor cells. 
C) They disrupt tumor cell membranes. 
D) They prevent the entry of cells into the first stage of meiosis. 
E) They inhibit mitochondria. 
A) They preferentially kill tumor cells. 
B) They preferentially stabilize tumor cells. 
C) They disrupt tumor cell membranes. 
D) They prevent the entry of cells into the first stage of meiosis. 
E) They inhibit mitochondria.

Question 12

Along which structure do membranous vesicles and organelles typically move long distances in an animal cell?

Accepted Answer

A) mitochondria 
B) microtubules 
C) microfilaments 
D) intermediate filaments 
E) lysosomes 
A) mitochondria 
B) microtubules 
C) microfilaments 
D) intermediate filaments 
E) lysosomes

Question 13

Bardet‐Biedl syndrome (BBS)is caused by mutations in any one of a number of genes that affect protein trafficking into cilia.Persons afflicted with BBS exhibit a remarkable range of abnormalities,like polydactyly,obesity,kidney disease,etc.These disparate symptoms are thought to reflect the function of cilia ________________.

Accepted Answer

A) as sensors for a magnetic field 
B) as locomotory organelles 
C) as sources of flagella 
D) as binding sites for actin 
E) as antennas to receive signals that regulate development and physiology 
A) as sensors for a magnetic field 
B) as locomotory organelles 
C) as sources of flagella 
D) as binding sites for actin 
E) as antennas to receive signals that regulate development and physiology

Question 14

Which of the following is normally associated with the cilia of organisms from protists to mammals?

Accepted Answer

A) a 9 + 0 pattern 
B) a 9 + 1 pattern 
C) a 9 + 2 pattern 
D) microtubules 
E) none of these choices 
A) a 9 + 0 pattern 
B) a 9 + 1 pattern 
C) a 9 + 2 pattern 
D) microtubules 
E) none of these choices

Question 15

Of what protein are the arms attached to the A microtubule of the axoneme composed?

Accepted Answer

A) tubulin 
B) actin 
C) dynein 
D) keratin 
E) myosin 
A) tubulin 
B) actin 
C) dynein 
D) keratin 
E) myosin

Question 16

Proteins that accelerate the polymerization of actin filaments are called ________.

Accepted Answer

A) nucleons 
B) nucleating proteins 
C) monomer-sequestering proteins 
D) end-blocking proteins 
E) nucleons and nucleating proteins 
A) nucleons 
B) nucleating proteins 
C) monomer-sequestering proteins 
D) end-blocking proteins 
E) nucleons and nucleating proteins

Question 17

In order to measure the step size of kinesin,a group of investigators attached a small silica bead to the tail of a kinesin molecule.What advantage(s)did the attached silica bead provide?

Accepted Answer

A) The bead made kinesin activity visible. 
B) The bead helped to denature kinesin making its properties easier to measure. 
C) The bead provided a handle for manipulating and holding the motor using an optical trap. 
D) The bead absorbed laser light in a manner proportional to the distance the motor moved. 
E) The bead made kinesin activity visible AND provided a handle for manipulating and holding the motor using an optical trap. 
A) The bead made kinesin activity visible. 
B) The bead helped to denature kinesin making its properties easier to measure. 
C) The bead provided a handle for manipulating and holding the motor using an optical trap. 
D) The bead absorbed laser light in a manner proportional to the distance the motor moved. 
E) The bead made kinesin activity visible AND provided a handle for manipulating and holding the motor using an optical trap.

Question 18

Which of the following is a plausible explanation for the fact that the chemical EGTA blocks microtubule disassembly?

Accepted Answer

A) EGTA binds to Ca2+ ions,which are known to induce microtubule depolymerization. 
B) EGTA binds to Mg2+ ions,which are known to induce microtubule depolymerization. 
C) EGTA binds to Ca2+ ions,which are known to induce microtubule polymerization. 
D) EGTA destroys Ca2+ ions,which are known to inhibit microtubule polymerization. 
E) EGTA destroys Mg2+ ions,which are known to inhibit microtubule polymerization. 
A) EGTA binds to Ca2+ ions,which are known to induce microtubule depolymerization. 
B) EGTA binds to Mg2+ ions,which are known to induce microtubule depolymerization. 
C) EGTA binds to Ca2+ ions,which are known to induce microtubule polymerization. 
D) EGTA destroys Ca2+ ions,which are known to inhibit microtubule polymerization. 
E) EGTA destroys Mg2+ ions,which are known to inhibit microtubule polymerization.

Question 19

A small zone of fluorescent microtubules in a cell is photobleached so that their fluorescent label gives off no light.Some time later fluorescence returns to the bleached zone in the cell.Which of the following is a possible explanation for the recovery of fluorescence in the region of the cell previously bleached?

Accepted Answer

A) the dynamics of the microtubules turning over in that bleached zone of the cell 
B) the growth of new microtubules into the bleached zone 
C) movement of microtubules through the bleached zone 
D) all of these choices 
E) the dynamics of the microtubules turning over in that bleached zone of the cell and the growth of new microtubules into the bleached zone 
A) the dynamics of the microtubules turning over in that bleached zone of the cell 
B) the growth of new microtubules into the bleached zone 
C) movement of microtubules through the bleached zone 
D) all of these choices 
E) the dynamics of the microtubules turning over in that bleached zone of the cell and the growth of new microtubules into the bleached zone

Question 20

Which type of cytoskeletal element is described as tough,ropelike fibers composed of a variety of related proteins like keratin?

Accepted Answer

A) microfilaments 
B) microtubules 
C) intermediate filaments 
D) macrofilaments 
E) indeterminate filaments 
A) microfilaments 
B) microtubules 
C) intermediate filaments 
D) macrofilaments 
E) indeterminate filaments

Which of the following is NOT a function of a cilium?

Which of the following molecules is a non-diffusible,integral protein of the plasma membrane that binds specifically to its receptor on the surface of the growth cone? This protein acts as a neuronal guidance factor.

The point at which the neuron axon terminus and the muscle fiber make contact is called the _________.

What is the direct source of energy that powers molecular motors?

The central,rod-shaped domain of an intermediate filament is flanked on each side by globular domains of variable size and sequence.What structure forms the core of the central,rod-shaped domain?

You inject labeled keratin subunits into cultured skin cells.What happens a few minutes later?

Which cytoskeletal element is found could be described as solid,thinner structures that are often organized into a branching network?

What would happen if you cultured a frog embryo just after gastrulation in the presence of colchicine?

The first direct measurement of a motor taking single steps was an analysis of _ stepping using ___.

The deletion of the creS gene in Caulobacter crescentus results in __________.

Why are taxol,vinblastine and other drugs like them used as chemotherapy agents?

Along which structure do membranous vesicles and organelles typically move long distances in an animal cell?

Which of the following is normally associated with the cilia of organisms from protists to mammals?

Of what protein are the arms attached to the A microtubule of the axoneme composed?

Proteins that accelerate the polymerization of actin filaments are called ________.

In order to measure the step size of kinesin,a group of investigators attached a small silica bead to the tail of a kinesin molecule.What advantage(s)did the attached silica bead provide?

Which of the following is a plausible explanation for the fact that the chemical EGTA blocks microtubule disassembly?

Which type of cytoskeletal element is described as tough,ropelike fibers composed of a variety of related proteins like keratin?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Exam 9: The Cytoskeleton and Cell Motility

Which of the following is NOT a function of a cilium?

Which of the following molecules is a non-diffusible,integral protein of the plasma membrane that binds specifically to its receptor on the surface of the growth cone? This protein acts as a neuronal guidance factor.

The point at which the neuron axon terminus and the muscle fiber make contact is called the _________.

What is the direct source of energy that powers molecular motors?

The central,rod-shaped domain of an intermediate filament is flanked on each side by globular domains of variable size and sequence.What structure forms the core of the central,rod-shaped domain?

You inject labeled keratin subunits into cultured skin cells.What happens a few minutes later?

Which cytoskeletal element is found could be described as solid,thinner structures that are often organized into a branching network?

What would happen if you cultured a frog embryo just after gastrulation in the presence of colchicine?

The first direct measurement of a motor taking single steps was an analysis of _______ stepping using _________.

The deletion of the creS gene in Caulobacter crescentus results in __________.

Why are taxol,vinblastine and other drugs like them used as chemotherapy agents?

Along which structure do membranous vesicles and organelles typically move long distances in an animal cell?

Which of the following is normally associated with the cilia of organisms from protists to mammals?

Of what protein are the arms attached to the A microtubule of the axoneme composed?

Proteins that accelerate the polymerization of actin filaments are called ________.

In order to measure the step size of kinesin,a group of investigators attached a small silica bead to the tail of a kinesin molecule.What advantage(s)did the attached silica bead provide?

Which of the following is a plausible explanation for the fact that the chemical EGTA blocks microtubule disassembly?

Which type of cytoskeletal element is described as tough,ropelike fibers composed of a variety of related proteins like keratin?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

The first direct measurement of a motor taking single steps was an analysis of _ stepping using ___.