Exam 26: Regulation of Gene Expression

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The physiological inducer of the lac operon is ________.

(Short Answer)
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In eukaryotes RNA polymerase is only bound at promoters that are carrying out active transcription.

(True/False)
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A partial diploid containing a wild type allele for lacO and a lacO mutant that was unable to bind to the lac repressor would always express β-galactosidase.

(True/False)
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The affinity of the lac repressor for DNA ________ markedly when the inducer binds to the lac repressor.

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Nucleosomes very close to the transcription start site in eukaryotes tend to have a high proportion of the histone variants H3.3 and H2A.Z.

(True/False)
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Which of the following is NOT part of initiation of transcription in eukaryotes?

(Multiple Choice)
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A set of linked genes regulated by a common mechanism is called a regulon.

(True/False)
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Chromatin modifications that tend to inhibit transcription include:

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The trp operon is transcribed when the trp repressor is bound to tryptophan.

(True/False)
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Transcriptionally active chromatin usually contains ________ histones, while ________ is normally inhibitory to transcription.

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Catabolite or glucose repression of the lac operon is a regulatory system, which depends on the levels of cAMP in the cell.

(True/False)
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Epigenetics is the heritable transmission of gene ________ patterns that does not involve a change in the DNA base sequence.

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