Exam 12: Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Anaerobic glycolysis can produce ATP at a much faster rate than aerobic oxidative phosphorylation.

Which of the following statements about regulation of phosphofructokinase is FALSE?

Much of the regulation of gluconeogenesis is a result of the inhibition of glycolysis.

Which statement about control of glycogen metabolism is INCORRECT?

The primary gluconeogenic organ in animals is:

Flux through the pentose phosphate pathway is controlled mainly by the NADP+/NADPH ratio in the cell.

________ from muscle working anaerobically is released to blood and can be taken up by liver where it is converted to pyruvate by the enzyme lactate dehydrogenase.

Fructose-1,6-bisphosphate is a feedforward ________ activator of liver pyruvate kinase.

Which of the following is NOT involved in glycogen synthesis?

Which of the following types of reaction does NOT occur in glycolysis?

The standard free energy change of the glycolytic pathway to pyruvate is -79.9 kJ/mol, while the standard free energy change associated with gluconeogenesis from pyruvate is -42.7 kJ/mol. What would the standard free energy change be for a direct reversal of the glycolytic pathway.

The pentose phosphate pathway provides ________ for reductive biosynthesis and ________ for nucleic acid biosynthesis.

Polysaccharide digestion and glycogen breakdown involve sequential cleavage from ________ ends of glucose polymers.

The major product from the action of glycogen phosphorylase and the debranching enzyme glucantransferase is ________.

The oxidation of glucose to lactate has a standard free energy change of approximately -196 kJ/mol. Calculate the efficiency of energy conversion if the standard free energy change for the production of ATP from ADP and inorganic phosphate is +32.2 kJ/mol.

Which of the following cannot be used as a precursor for gluconeogenesis?

Both glycolysis and gluconeogenesis are controlled by fructose 2,6-bisphosphate in response to hormones.

Phosphorylases and phosphatases catalyze the same reaction, the removal of a phosphate group.

Glycolysis is regulated primarily by:

Pyruvate carboxylase and phosphoenolpyruvate carboxykinase catalyze reactions of gluconeogenesis that bypass the reaction of glycolysis that is catalyzed by ________.