Question 1

Stabilization of a charge by an opposite charge is called ________ catalysis.

Accepted Answer

A) electrostatic 
B) osmotic 
C) substrate 
D) activated 
E) covalent 
A) electrostatic 
B) osmotic 
C) substrate 
D) activated 
E) covalent

Question 2

Explain why an intramolecular reaction resulting in the formation of five- or six-membered rings occurs more readily than the corresponding intermolecular reaction.

Accepted Answer

An intramolecular reaction has

Question 3

How does an acid catalyst increase the rate of reaction?

Accepted Answer

by donatin

Question 4

Which of the following is a step in the mechanism of the reaction shown below?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 5

Explain what is meant by site-specific mutagenesis.

Accepted Answer

It is a technique for determin

Question 6

Which of the following residues acts as a general-acid catalyst in aldolase but as a general-base catalyst in chymotrypsin?

Accepted Answer

A) methionine 
B) histidine 
C) cysteine 
D) asparagine 
E) lysine 
A) methionine 
B) histidine 
C) cysteine 
D) asparagine 
E) lysine

Question 7

Which of the labeled bonds in the following peptide chain will break when carboxypeptidase A is used to hydrolyze the chain?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
E) 5 
A) 1 
B) 2 
C) 3 
D) 4 
E) 5

Question 8

Pyruvate contains

Accepted Answer

A) 3 carbons. 
B) 4 carbons. 
C) 5 carbons. 
D) 6 carbons. 
E) 0 carbons. 
A) 3 carbons. 
B) 4 carbons. 
C) 5 carbons. 
D) 6 carbons. 
E) 0 carbons.

Question 9

Which of the following residues acts as a general-base catalyst in the cleavage of the C3-C4 bond in the mechanism of the aldolase-catalyzed reaction?

Accepted Answer

A) methionine 
B) histidine 
C) cysteine 
D) asparagine 
E) lysine 
A) methionine 
B) histidine 
C) cysteine 
D) asparagine 
E) lysine

Question 10

Which of the following is not true about metal-ion catalysts?

Accepted Answer

A) They coordinate with atoms with nonbonded electrons. 
B) They can make a reaction center more susceptible to receiving electrons and stabilize a developing charge on the transition state. 
C) They can make a leaving group a weaker base and therefore a better leaving group. 
D) They act as Lewis bases. 
E) They can increase the electrophilicity of a reaction center. 
A) They coordinate with atoms with nonbonded electrons. 
B) They can make a reaction center more susceptible to receiving electrons and stabilize a developing charge on the transition state. 
C) They can make a leaving group a weaker base and therefore a better leaving group. 
D) They act as Lewis bases. 
E) They can increase the electrophilicity of a reaction center.

Question 11

A nucleophilic catalyst increases the rate of the reaction by

Accepted Answer

A) reacting as a nucleophile and forming a new covalent bond. 
B) complexing with an atom with lone pair. 
C) protonating the reactant. 
D) reacting as an acid. 
E) none of the above. 
A) reacting as a nucleophile and forming a new covalent bond. 
B) complexing with an atom with lone pair. 
C) protonating the reactant. 
D) reacting as an acid. 
E) none of the above.

Question 12

How does Cu2+ catalyze the decarboxylation of dimethyloxaloacetate?

Accepted Answer

Cu²⁺ binds to two oxygen atoms a

Stabilization of a charge by an opposite charge is called ________ catalysis.

Explain why an intramolecular reaction resulting in the formation of five- or six-membered rings occurs more readily than the corresponding intermolecular reaction.

How does an acid catalyst increase the rate of reaction?

Which of the following is a step in the mechanism of the reaction shown below?

Explain what is meant by site-specific mutagenesis.

Which of the following residues acts as a general-acid catalyst in aldolase but as a general-base catalyst in chymotrypsin?

Which of the labeled bonds in the following peptide chain will break when carboxypeptidase A is used to hydrolyze the chain?

Pyruvate contains

Which of the following residues acts as a general-base catalyst in the cleavage of the C₃-C₄ bond in the mechanism of the aldolase-catalyzed reaction?

Which of the following is not true about metal-ion catalysts?

A nucleophilic catalyst increases the rate of the reaction by

How does Cu²⁺ catalyze the decarboxylation of dimethyloxaloacetate?

Remembering General Chemistry: Electronic Structure and Bonding

Acids and Bases: Central to Understanding Organic Chemistry

An Introduction to Organic Compounds: Nomenclature, physical Properties, and Structure

Isomers: the Arrangement of Atoms in Space

Alkenes: Structure,nomenclature,and an Introduction to Reactivity - Thermodynamics and Kinetics

The Reactions of Alkenes - the Stereochemistry of Addition Reactions

The Reactions of Alkynes - Introduction to Multistep Synthesis

Delocalized Electrons: Their Effect on Stability, pka, and the Products of a Reaction - Aromaticity and Electronic Effects: an Introduction to the Reactions of Benzene

Substitution and Elimination Reactions of Alkyl Halides

Reactions of Alcohols, ethers, epoxides, amines and Sulfur-Containing Compounds

Organometallic Compounds

Radicals

Mass Spectrometry,infrared Spectroscopy,and Uvvis Spectroscopy

Nmr Spectroscopy

Reactions of Carboxylic Acids and Carboxylic Acid Derivatives

Reactions of Aldehydes and Ketones

Reactions at the Α-Carbon

Reactions of Benzene and Substituted Benzenes

More About Amines - Reactions of Heterocylic Compounds

The Organic Chemistry of Carbohydrates

Amino Acids,peptides,and Proteins

The Organic Chemistry of the Coenzymes, compounds Derived From Vitamins

The Organic Chemistry of the Metabolic Pathways

The Organic Chemistry of Lipids

The Chemistry of the Nucleic Acids

Synthetic Polymers

Pericyclic Reactions

Filters

Exam 22: Catalysis in Organic Reactions and in Enzymatic Reactions

Stabilization of a charge by an opposite charge is called ________ catalysis.

Explain why an intramolecular reaction resulting in the formation of five- or six-membered rings occurs more readily than the corresponding intermolecular reaction.

How does an acid catalyst increase the rate of reaction?

Which of the following is a step in the mechanism of the reaction shown below?

Explain what is meant by site-specific mutagenesis.

Which of the following residues acts as a general-acid catalyst in aldolase but as a general-base catalyst in chymotrypsin?

Which of the labeled bonds in the following peptide chain will break when carboxypeptidase A is used to hydrolyze the chain?

Pyruvate contains

Which of the following residues acts as a general-base catalyst in the cleavage of the C3-C4 bond in the mechanism of the aldolase-catalyzed reaction?

Which of the following is not true about metal-ion catalysts?

A nucleophilic catalyst increases the rate of the reaction by

How does Cu2+ catalyze the decarboxylation of dimethyloxaloacetate?

Remembering General Chemistry: Electronic Structure and Bonding

Acids and Bases: Central to Understanding Organic Chemistry

An Introduction to Organic Compounds: Nomenclature, physical Properties, and Structure

Isomers: the Arrangement of Atoms in Space

Alkenes: Structure,nomenclature,and an Introduction to Reactivity - Thermodynamics and Kinetics

The Reactions of Alkenes - the Stereochemistry of Addition Reactions

The Reactions of Alkynes - Introduction to Multistep Synthesis

Delocalized Electrons: Their Effect on Stability, pka, and the Products of a Reaction - Aromaticity and Electronic Effects: an Introduction to the Reactions of Benzene

Substitution and Elimination Reactions of Alkyl Halides

Reactions of Alcohols, ethers, epoxides, amines and Sulfur-Containing Compounds

Organometallic Compounds

Radicals

Mass Spectrometry,infrared Spectroscopy,and Uvvis Spectroscopy

Nmr Spectroscopy

Reactions of Carboxylic Acids and Carboxylic Acid Derivatives

Reactions of Aldehydes and Ketones

Reactions at the Α-Carbon

Reactions of Benzene and Substituted Benzenes

More About Amines - Reactions of Heterocylic Compounds

The Organic Chemistry of Carbohydrates

Amino Acids,peptides,and Proteins

The Organic Chemistry of the Coenzymes, compounds Derived From Vitamins

The Organic Chemistry of the Metabolic Pathways

The Organic Chemistry of Lipids

The Chemistry of the Nucleic Acids

Synthetic Polymers

Pericyclic Reactions

Filters

Which of the following residues acts as a general-base catalyst in the cleavage of the C₃-C₄ bond in the mechanism of the aldolase-catalyzed reaction?

How does Cu²⁺ catalyze the decarboxylation of dimethyloxaloacetate?