Question 1

Consider the set of compounds,NH3,HF,and H2O.Rank these compounds in order of increasing acidity and discuss your rationale.

Accepted Answer

NH₃ < H₂O < HF When determining relative a

Question 2

What is the product of the following Lewis acid-base reaction?

Accepted Answer

The answer of What is the product of the following...

Question 3

At what pH will 25% of a compound with a pKa of 5.3 be in its basic form?

Accepted Answer

The answer of At what pH will 25% of a...

Question 4

What would be the conjugate acid in the following acid base reaction?

Accepted Answer

A) CH2O 
B) CH3OH 
C) CH3SH2+ 
D) CH3S- 
E) H2O 
A) CH2O 
B) CH3OH 
C) CH3SH2+ 
D) CH3S- 
E) H2O

Question 5

When a small amount of hexanoic acid [CH3(CH2)4CO2H,pKa~4.8],is added to a separatory funnel which contains the organic solvent diethyl ether and water with a pH of 12.0,it is found mainly in the ________ phase as ________.

Accepted Answer

A) ether; CH3(CH2)4CO2- 
B) water; CH3(CH2)4CO2- 
C) ether; CH3(CH2)4CO2H 
D) water; CH3(CH2)4CO2H 
E) none of the above 
A) ether; CH3(CH2)4CO2- 
B) water; CH3(CH2)4CO2- 
C) ether; CH3(CH2)4CO2H 
D) water; CH3(CH2)4CO2H 
E) none of the above

Question 6

The conjugate acid of H2O is

Accepted Answer

A) H3O-. 
B) H3O. 
C) H3O+. 
D) HO-. 
E) H2O+. 
A) H3O-. 
B) H3O. 
C) H3O+. 
D) HO-. 
E) H2O+.

Question 7

Draw a resonance contributor and the resonance hybrid for HOCO2-.

Accepted Answer

resonance

Question 8

Which of the following is the strongest acid?

Accepted Answer

A) CH3OH 
B) CH3OH2+ 
C) H2N- 
D) CH3NH2 
E) CH3NH3+ 
A) CH3OH 
B) CH3OH2+ 
C) H2N- 
D) CH3NH2 
E) CH3NH3+

Question 9

If H2O has a pKa value of 15.7 and HF has a pKa value of 3.2,which is a stronger base,HO- or F-? Explain.

Accepted Answer

HO^- is a stronger base than F^- b

Question 10

What is the conjugate base of CH3NH2?

Accepted Answer

A) CH3NH3+ 
B) CH3NH- 
C) NH4+ 
D) NH2- 
A) CH3NH3+ 
B) CH3NH- 
C) NH4+ 
D) NH2-

Question 11

2-Propanol is shown below.Draw the structure of its conjugate base.
(CH3)2CHOH

Accepted Answer

Question 12

Predict the direction of equilibrium in the following reaction.Explain your answer.

Accepted Answer

Right Conjugate base on the ri

Question 13

Propanoic acid,CH3CH2COOH,has a pKa =4.9.Draw the structure of the conjugate base of propanoic acid and give the pH above which 90% of the compound will be in this conjugate base form.

Accepted Answer

Question 14

Identify the compound with the highest pKa.

Accepted Answer

A) CH3NH2 
B) CH3OH 
C) CH3COOH 
D) H2O 
E) CH3NH3+ 
A) CH3NH2 
B) CH3OH 
C) CH3COOH 
D) H2O 
E) CH3NH3+

Question 15

What is the product formed from the following acid-base reaction when ammonia functions as a base? The equilibrium lies far to the reactants.

Accepted Answer

A) CH3O- + +NH4 
B) CH2OH + +NH3 
C) CH3OH2+ + -NH2 
D) CH3NH2 + H2O 
E) CH4 + NH2OH 
A) CH3O- + +NH4 
B) CH2OH + +NH3 
C) CH3OH2+ + -NH2 
D) CH3NH2 + H2O 
E) CH4 + NH2OH

Question 16

Structure of Lorazepam,a widely known drug for short-term anxiety is shown below.Is the indicated lone pair localized or delocalized?

Accepted Answer

The answer of Structure of Lorazepam,a widely known drug for...

Question 17

Which of the following is the strongest acid?

Accepted Answer

A) HF 
B) H2O 
C) : NH3 
D) CH4 
E) CH3OH 
A) HF 
B) H2O 
C) : NH3 
D) CH4 
E) CH3OH

Question 18

Would you predict trifluoromethanesulfonic acid,CF3SO3H,to be a stronger or weaker acid than methanesulfonic acid,CH3SO3H? Explain your reasoning.

Accepted Answer

Trifluoromethanesulfonic acid is a stron

Question 19

Which of the following is not a conjugate acid-base pair?

Accepted Answer

A) (H2O,HO-) 
B) (H2O,H3O+) 
C) (HSO4-,H2SO4) 
D) (-OH,O2-) 
E) (NO3-,NO2-) 
A) (H2O,HO-) 
B) (H2O,H3O+) 
C) (HSO4-,H2SO4) 
D) (-OH,O2-) 
E) (NO3-,NO2-)

Question 20

H-A is an acid with a pKa of 4.5.Which of the following statements about an aqueous solution of H-A is true?

Accepted Answer

A) At pH = 4.5,the solution contains much more H-A than.A-. 
B) At pH = 4.5,the solution contains much more A- than H-A. 
C) At pH- 3.5,the solution contains about 90% A- and 10% H-A. 
D) At pH = 6.5,the solution contains about 80% A- and 20% H-A. 
E) At pH = 5.5,the solution contains about 90% A- and 10% H-A. 
A) At pH = 4.5,the solution contains much more H-A than.A-. 
B) At pH = 4.5,the solution contains much more A- than H-A. 
C) At pH- 3.5,the solution contains about 90% A- and 10% H-A. 
D) At pH = 6.5,the solution contains about 80% A- and 20% H-A. 
E) At pH = 5.5,the solution contains about 90% A- and 10% H-A.

Exam 2: Acids and Bases: Central to Understanding Organic Chemistry

Consider the set of compounds,NH3,HF,and H2O.Rank these compounds in order of increasing acidity and discuss your rationale.

What is the product of the following Lewis acid-base reaction?

At what pH will 25% of a compound with a pKa of 5.3 be in its basic form?

What would be the conjugate acid in the following acid base reaction?

When a small amount of hexanoic acid [CH3(CH2)4CO2H,pKa~4.8],is added to a separatory funnel which contains the organic solvent diethyl ether and water with a pH of 12.0,it is found mainly in the ________ phase as ________.

The conjugate acid of H2O is

Draw a resonance contributor and the resonance hybrid for HOCO2-.

Which of the following is the strongest acid?

If H2O has a pKa value of 15.7 and HF has a pKa value of 3.2,which is a stronger base,HO- or F-? Explain.

What is the conjugate base of CH3NH2?

2-Propanol is shown below.Draw the structure of its conjugate base. (CH3)2CHOH

Predict the direction of equilibrium in the following reaction.Explain your answer.

Propanoic acid,CH3CH2COOH,has a pKa =4.9.Draw the structure of the conjugate base of propanoic acid and give the pH above which 90% of the compound will be in this conjugate base form.

Identify the compound with the highest pKa.

What is the product formed from the following acid-base reaction when ammonia functions as a base? The equilibrium lies far to the reactants.

Structure of Lorazepam,a widely known drug for short-term anxiety is shown below.Is the indicated lone pair localized or delocalized?

Which of the following is the strongest acid?

Would you predict trifluoromethanesulfonic acid,CF3SO3H,to be a stronger or weaker acid than methanesulfonic acid,CH3SO3H? Explain your reasoning.

Which of the following is not a conjugate acid-base pair?

H-A is an acid with a pKa of 4.5.Which of the following statements about an aqueous solution of H-A is true?

Remembering General Chemistry: Electronic Structure and Bonding

An Introduction to Organic Compounds: Nomenclature, physical Properties, and Structure

Isomers: the Arrangement of Atoms in Space

Alkenes: Structure,nomenclature,and an Introduction to Reactivity - Thermodynamics and Kinetics

The Reactions of Alkenes - the Stereochemistry of Addition Reactions

The Reactions of Alkynes - Introduction to Multistep Synthesis

Delocalized Electrons: Their Effect on Stability, pka, and the Products of a Reaction - Aromaticity and Electronic Effects: an Introduction to the Reactions of Benzene

Substitution and Elimination Reactions of Alkyl Halides

Reactions of Alcohols, ethers, epoxides, amines and Sulfur-Containing Compounds

Organometallic Compounds

Radicals

Mass Spectrometry,infrared Spectroscopy,and Uvvis Spectroscopy

Nmr Spectroscopy

Reactions of Carboxylic Acids and Carboxylic Acid Derivatives

Reactions of Aldehydes and Ketones

Reactions at the Α-Carbon

Reactions of Benzene and Substituted Benzenes

More About Amines - Reactions of Heterocylic Compounds

The Organic Chemistry of Carbohydrates

Amino Acids,peptides,and Proteins

Catalysis in Organic Reactions and in Enzymatic Reactions

The Organic Chemistry of the Coenzymes, compounds Derived From Vitamins

The Organic Chemistry of the Metabolic Pathways

The Organic Chemistry of Lipids

The Chemistry of the Nucleic Acids

Synthetic Polymers

Pericyclic Reactions

Filters

Consider the set of compounds,NH₃,HF,and H₂O.Rank these compounds in order of increasing acidity and discuss your rationale.

When a small amount of hexanoic acid [CH₃(CH₂)₄CO₂H,pK_a~4.8],is added to a separatory funnel which contains the organic solvent diethyl ether and water with a pH of 12.0,it is found mainly in the phase as .

The conjugate acid of H₂O is

Draw a resonance contributor and the resonance hybrid for HOCO₂^-.

If H₂O has a pK_a value of 15.7 and HF has a pK_a value of 3.2,which is a stronger base,HO^- or F^-? Explain.

What is the conjugate base of CH₃NH₂?

2-Propanol is shown below.Draw the structure of its conjugate base. (CH₃)₂CHOH

Propanoic acid,CH₃CH₂COOH,has a pKa =4.9.Draw the structure of the conjugate base of propanoic acid and give the pH above which 90% of the compound will be in this conjugate base form.

Identify the compound with the highest pK_a.

Would you predict trifluoromethanesulfonic acid,CF₃SO₃H,to be a stronger or weaker acid than methanesulfonic acid,CH₃SO₃H? Explain your reasoning.