Exam 13: Carbohydrate Metabolism: Glycolysis, gluconeogenesis, glycogen Metabolism, and the Pentose Phosphate Pathway

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The conversion of phosphoenolpyruvate and ADP to pyruvate and ATP occurs in two distinct steps,first the transfer of the phosphate from PEP to ADP,then the conversion of enolpyruvate to pyruvate.Which of the following describes the reversibility of this process?

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If a residue of glucose in glycogen is removed from the glycogen molecule and then allowed to proceed through glycolysis to pyruvate,what is the net production of ATP?

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Which of the following enzymes is activated when acted on by phosphoprotein phosphatase 1?

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During the oxidation of glyceraldehyde-3-phosphate,what intermediate in the enzyme-catalyzed mechanism actually undergoes oxidation?

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Under conditions of strenuous exercise,gluconeogenesis occurs primarily in the _______ using _______ formed in the skeletal muscle

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When lipid biosynthesis is active using carbohydrates as a source of carbon,three things are needed: NADPH,ATP and acetyl-CoA (from pyruvate).Which of the following best explains the operation of the pentose phosphate pathway (PPP)under such conditions? G6P = glucose-6-phosphate,F6P = fructose-6-phosphate,G3P = glyceraldehyde-3-phosphate

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The conversion of 3-phosphoglycerate to phosphoenolpyruvate requires two reactions.Which of the following correctly identifies the types of reactions in the proper order of glycolysis?

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Which isoform of hexokinase is found in the vertebrate liver?

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Besides its role in glycogen synthesis,which of the following directly relies on UDP-glucose?

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Besides two molecules of pyruvate,what are the net products of glycolysis?

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Which of the following pairs of phosphorylated molecules contains an intermediate of glycolysis with high phosphate transfer potential and one with low phosphate transfer potential?

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During the energy investment phase of glycolysis,_____ reaction(s)use ATP as a substrate while during the energy generation phase,_____ reactions produce ATP as a product.

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If unregulated,which of the following pairs of enzymes would represent a futile cycle?

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What sequence of enzymes allows for the synthesis of glycogen from glucose-6-phosphate?

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With respect to carbons 1 and 2 of the intermediate in the conversion of glucose-6-phosphate to fructose-6-phosphate,which of the following would best describe this intermediate?

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Which of the following glycolytic reactions is freely reversible?

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A transketolase enzyme transfers a _____ carbon fragment from a(n)________ to a(n)________.

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Which of the following enzymes is used by the gluconeogenic pathway but not the glycolytic pathway?

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Which of the following activators is correctly paired with the glycolytic or gluconeogenic enzyme that it activates?

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Which enzyme catalyzes the primary regulation site of glycolysis?

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