Exam 15: Drug Addiction and the Brain’s Reward Circuits

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In the conditioned place-preference paradigm, rats usually prefer the

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Which drug has been shown to increase the rate of cancer and heart disease in nonusers of the drug who are living with users of the drug?

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Recent research suggests that dopamine release in the nucleus accumbens is more related to____________ than to _____________.

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The animal model that best approximates human drug addiction is the

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Tobacco is a leading cause of preventable death; worldwide, it contributes to over 5 __________ premature deaths per year.

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Which of the following is the strongest psychoactive ingredient of opium?

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Individuals who experience drug withdrawal effects are, by definition,

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Restlessness, watery eyes, running nose, yawning, and sweating are all early signs of withdrawal from

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Which of the following drugs produces Buerger's disease?

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Globally, more than 1 billion people are addicted to _____________ , and more than 76 million are addicted to _____________ .

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Evidence indicates that one serious health hazard of marijuana is

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Support for the theory that tolerance is triggered by drug-induced changes in neural activity rather than from drug exposure per se came from the finding in one study that tolerance did not develop to the anticonvulsant effects of alcohol unless

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Tolerance that occurs because the target tissue becomes less reactive to the drug after exposure is

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According to the incentive-sensitization theory of drug addiction, as an addict habitually consumes the drug, the

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Dr. William Stewart Halsted, a brilliant surgeon and one of the founders of Johns Hopkins Medical School, is considered by many to be the father of modern surgery. Surprisingly, he was addicted to __________ throughout most of his brilliant career.

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Studies of electrical intracranial self-stimulation have influenced the development of biopsychological theories of addiction by indicating that

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Recent research suggests that in addicts dopamine release in the nucleus accumbens may be related more to the __________ of a drug than the liking of the drug.

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Drug tolerance can be defined as a shift in the dose-response curve to the __________.

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Although causal effects have not yet been proven, the well-established correlation between heavy marijuana use and ____________ is cause for concern.

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Which of the following drugs is a stimulant?

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