Question 1

Which of the following is true regarding the model organism C.elegans?

Accepted Answer

A)  C. elegans completes its life cycle in three days. 
B)  C. elegans is a hermaphroditic species. 
C)  Self fertilization is possible. 
D)  All of these are true. 
E)  None of these are true. 
A)  C. elegans completes its life cycle in three days. 
B)  C. elegans is a hermaphroditic species. 
C)  Self fertilization is possible. 
D)  All of these are true. 
E)  None of these are true.

Question 2

Which of the following methods can be used to identify genes that are involved in important developmental events?

Accepted Answer

A)  Collect mutations and test for allelism 
B)  RT-PCR 
C)  Fluorescent labeling 
D)  RNA and protein blotting 
E)  All of these are correct. 
A)  Collect mutations and test for allelism 
B)  RT-PCR 
C)  Fluorescent labeling 
D)  RNA and protein blotting 
E)  All of these are correct.

Question 3

What is encoded by the somatic sex determination pathway in C.elegans?
1)Proteins that regulate RNA splicing
2)Signaling molecules
3)Signaling receptors

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  1 and 2 
E)  2 and 3 
A)  1 
B)  2 
C)  3 
D)  1 and 2 
E)  2 and 3

Question 4

How many "founder" cells are produced by the series of asymmetric cell divisions in C.elegans?

Accepted Answer

A)  1 
B)  2 
C)  4 
D)  6 
E)  8 
A)  1 
B)  2 
C)  4 
D)  6 
E)  8

Question 5

Which statement is false concerning zebra fish?

Accepted Answer

A)  Morpholinos are used to block the translation of specific transcripts. 
B)  Morpholinos do not act over a very long period of time after injection into fertilized eggs. 
C)  Its genome is 1.5 billion bp in length and contains 22,000 known and predicted genes. 
D)  Zebra fish have become a model genetic organism for vertebrates. 
E)  None of these 
A)  Morpholinos are used to block the translation of specific transcripts. 
B)  Morpholinos do not act over a very long period of time after injection into fertilized eggs. 
C)  Its genome is 1.5 billion bp in length and contains 22,000 known and predicted genes. 
D)  Zebra fish have become a model genetic organism for vertebrates. 
E)  None of these

Question 6

Explain how the developmental signal controls sex determination in Drosophila?

Accepted Answer

Once the X:A ratio has been ascertained,

Question 7

Which of the following organisms are considered to be premier model organisms for the genetic analysis of animal development?

Accepted Answer

A)  Drosophila 
B)  C. elegans 
C)  Chickens 
D)  Drosophila and C. elegans 
E)  All of these are correct. 
A)  Drosophila 
B)  C. elegans 
C)  Chickens 
D)  Drosophila and C. elegans 
E)  All of these are correct.

Question 8

Which of the following is a gene product that can participate in a developmental pathway?

Accepted Answer

A)  Signal molecules 
B)  Signal receptors 
C)  Signal transducers 
D)  Transcription factors 
E)  All of these are correct. 
A)  Signal molecules 
B)  Signal receptors 
C)  Signal transducers 
D)  Transcription factors 
E)  All of these are correct.

Question 9

In Drosophila with two X chromosomes and three pairs of autosomes (genotype XX; AAA),how do flies develop?

Accepted Answer

A)  They become males. 
B)  They become females. 
C)  They become intersex flies. 
D)  They do not develop as this is lethal. 
E)  They become hermaphrodites. 
A)  They become males. 
B)  They become females. 
C)  They become intersex flies. 
D)  They do not develop as this is lethal. 
E)  They become hermaphrodites.

Question 10

Which of the following is an example of colinearity?

Accepted Answer

A)  Replacement of a normal allele by a mutated transgene 
B)  Migration of cells during embryogenesis to form three primary germ layers 
C)  A process in which cells are assigned developmental fates 
D)  The physical order of genes corresponding to their expression along the anterior-posterior axis 
E)  Genetic dissection of a developmental pathway by analyzing gene mutations 
A)  Replacement of a normal allele by a mutated transgene 
B)  Migration of cells during embryogenesis to form three primary germ layers 
C)  A process in which cells are assigned developmental fates 
D)  The physical order of genes corresponding to their expression along the anterior-posterior axis 
E)  Genetic dissection of a developmental pathway by analyzing gene mutations

Question 11

The identity of each body segment in Drosophila is determined by the products of genes in which of the following complexes?

Accepted Answer

A)  Bithorax 
B)  Antennapedia 
C)  Femurtibia 
D)  Bithorax and antennapedia 
E)  Antennapedia and femurtibia 
A)  Bithorax 
B)  Antennapedia 
C)  Femurtibia 
D)  Bithorax and antennapedia 
E)  Antennapedia and femurtibia

Question 12

Which of the following statements best characterizes a homeotic gene?

Accepted Answer

A)  They define segmental regions in the embryo. 
B)  They define the anterior and posterior compartments of individual segments. 
C)  Mutations in these genes cause one body part to look like another. 
D)  They are responsible for sex determination. 
E)  They are involved in gene dosage compensation. 
A)  They define segmental regions in the embryo. 
B)  They define the anterior and posterior compartments of individual segments. 
C)  Mutations in these genes cause one body part to look like another. 
D)  They are responsible for sex determination. 
E)  They are involved in gene dosage compensation.

Question 13

Which of the following is a segmentation gene discovered along the anterior-posterior axis?

Accepted Answer

A)  Gap genes 
B)  Pair-rule genes 
C)  Segment polarity genes 
D)  Gap genes and Pair-rule genes 
E)  All of these are correct. 
A)  Gap genes 
B)  Pair-rule genes 
C)  Segment polarity genes 
D)  Gap genes and Pair-rule genes 
E)  All of these are correct.

Question 14

In C.elegans loss-of-function mutations in the two transformer genes tra-1 and tra-2 cause XX animals

Accepted Answer

A)  to develop as normal females. 
B)  to develop as males. 
C)  to develop as hermaphrodites. 
D)  to develop as intersex individuals. 
E)  None of these are correct. 
A)  to develop as normal females. 
B)  to develop as males. 
C)  to develop as hermaphrodites. 
D)  to develop as intersex individuals. 
E)  None of these are correct.

Question 15

Which of the following mutations were used to study the genetic control of anatomically correct organ formation?

Accepted Answer

A)  Eyeless 
B)  Wingless 
C)  Hunchback 
D)  Nanos 
E)  Bithorax 
A)  Eyeless 
B)  Wingless 
C)  Hunchback 
D)  Nanos 
E)  Bithorax

Question 16

During Drosophila development,each egg is surrounded by a tough shell-like structure that is made of materials synthesized by somatic cells in the ovary.This structure is called the

Accepted Answer

A)  micropyle. 
B)  chorion. 
C)  syncytium. 
D)  cellular blastoderm. 
E)  imaginal disc. 
A)  micropyle. 
B)  chorion. 
C)  syncytium. 
D)  cellular blastoderm. 
E)  imaginal disc.

Question 17

What are maternal-effect genes and how can they be identified?

Accepted Answer

Mutations in genes that contribute to th

Question 18

Mutations in genes that contribute to the formation of healthy eggs may have no effect on the viability or appearance of the female making those eggs.These are known as

Accepted Answer

A)  maternal effect mutations. 
B)  paternal effect mutations. 
C)  maternal gene mutations. 
D)  maternal offspring mutations. 
E)  embryo mutations. 
A)  maternal effect mutations. 
B)  paternal effect mutations. 
C)  maternal gene mutations. 
D)  maternal offspring mutations. 
E)  embryo mutations.

Question 19

Which of the following is not a reason why C.elegans is an excellent model system for studying development?

Accepted Answer

A)  The animal has a life cycle that is completed in three days. 
B)  It is a hermaphrodite species. 
C)  It is a transparent animal. 
D)  It has invariant cell lineages that form tissue of the adult. 
E)  XO mutants produced by meiotic disjunction are sterile. 
A)  The animal has a life cycle that is completed in three days. 
B)  It is a hermaphrodite species. 
C)  It is a transparent animal. 
D)  It has invariant cell lineages that form tissue of the adult. 
E)  XO mutants produced by meiotic disjunction are sterile.

Question 20

Therapeutic cloning

Accepted Answer

A)  involves producing ES cells by injecting a somatic cell nucleus into an enucleated egg. 
B)  is the same as reproductive cloning. 
C)  involves producing individuals from ES cell nuclei injected into an enucleated egg. 
D)  All of these are correct. 
E)  None of these are correct. 
A)  involves producing ES cells by injecting a somatic cell nucleus into an enucleated egg. 
B)  is the same as reproductive cloning. 
C)  involves producing individuals from ES cell nuclei injected into an enucleated egg. 
D)  All of these are correct. 
E)  None of these are correct.

Exam 20: The Genetic Control Of Animal Development

Which of the following is true regarding the model organism C.elegans?

Which of the following methods can be used to identify genes that are involved in important developmental events?

What is encoded by the somatic sex determination pathway in C.elegans? 1)Proteins that regulate RNA splicing 2)Signaling molecules 3)Signaling receptors

How many "founder" cells are produced by the series of asymmetric cell divisions in C.elegans?

Which statement is false concerning zebra fish?

Explain how the developmental signal controls sex determination in Drosophila?

Which of the following organisms are considered to be premier model organisms for the genetic analysis of animal development?

Which of the following is a gene product that can participate in a developmental pathway?

In Drosophila with two X chromosomes and three pairs of autosomes (genotype XX; AAA),how do flies develop?

Which of the following is an example of colinearity?

The identity of each body segment in Drosophila is determined by the products of genes in which of the following complexes?

Which of the following statements best characterizes a homeotic gene?

Which of the following is a segmentation gene discovered along the anterior-posterior axis?

In C.elegans loss-of-function mutations in the two transformer genes tra-1 and tra-2 cause XX animals

Which of the following mutations were used to study the genetic control of anatomically correct organ formation?

During Drosophila development,each egg is surrounded by a tough shell-like structure that is made of materials synthesized by somatic cells in the ovary.This structure is called the

What are maternal-effect genes and how can they be identified?

Mutations in genes that contribute to the formation of healthy eggs may have no effect on the viability or appearance of the female making those eggs.These are known as

Which of the following is not a reason why C.elegans is an excellent model system for studying development?

Therapeutic cloning

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