Question 1

Which of the following is a phenotypic function that genetic material must be able to perform?

Accepted Answer

A)  Replication 
B)  Mutation 
C)  Adaptation 
D)  Gene expression 
E)  Translation 
A)  Replication 
B)  Mutation 
C)  Adaptation 
D)  Gene expression 
E)  Translation D

Question 2

Which of the following is a genotypic function that the genetic material must be able to perform?

Accepted Answer

A)  Replication 
B)  Mutation 
C)  Adaptation 
D)  Gene expression 
E)  Translation 
A)  Replication 
B)  Mutation 
C)  Adaptation 
D)  Gene expression 
E)  Translation A

Question 3

Which large organic molecules are essential chromosome components?

Accepted Answer

A)  Lipids and proteins 
B)  Proteins and nucleic acids 
C)  Nucleic acids and polysaccharides 
D)  Proteins and polysaccharides 
A)  Lipids and proteins 
B)  Proteins and nucleic acids 
C)  Nucleic acids and polysaccharides 
D)  Proteins and polysaccharides B

Question 4

A single strand of a double-stranded helix has the sequence 5'-GTTTAACGTAT-3'.If the helix was in B-form,how many turns (360 degrees)would the helix make?

Accepted Answer

A)  1 
B)  1.1 
C)  1.5 
D)  2 
E)  2.1 
A)  1 
B)  1.1 
C)  1.5 
D)  2 
E)  2.1

Question 5

Compare the structure of DNA to the structure of RNA.Include at least three differences.

Accepted Answer

In DNA,the sugar is 2-deoxyribose (thus

Question 6

What were the two major pieces of evidence that led to the deduction of DNA structure by Watson and Crick and who supplied this information?

Accepted Answer

Chargaff: Ratio of A-to-T and

Question 7

Which type of chemical bond attaches deoxyribose molecules together to form the backbone of a DNA molecule?

Accepted Answer

A)  Hydrogen 
B)  Phosphodiester 
C)  Peptide 
D)  Ionic 
E)  Covalent 
A)  Hydrogen 
B)  Phosphodiester 
C)  Peptide 
D)  Ionic 
E)  Covalent

Question 8

Which of the following statements concerning the various forms of DNA is incorrect?

Accepted Answer

A)  B-DNA is the conformation under physiological conditions. 
B)  A-DNA occurs in a partially dehydrated environment. 
C)  DNA-RNA duplexes exist in an A-form. 
D)  B and Z are right handed helices, while A is left handed. 
E)  All of these are incorrect 
A)  B-DNA is the conformation under physiological conditions. 
B)  A-DNA occurs in a partially dehydrated environment. 
C)  DNA-RNA duplexes exist in an A-form. 
D)  B and Z are right handed helices, while A is left handed. 
E)  All of these are incorrect

Question 9

The pathogenic effects of prions are thought to result from:

Accepted Answer

A)  Viroids acting as a template for the synthesis of the prion proteins 
B)  Aberrant forms of mammalian cellular proteins that convert more mammalian cellular proteins to aberrant forms, leading to a clumping of the proteins, eventually killing the cell. 
C)  Prions converting viroids into abberant proteins that kill the cell 
D)  All of these 
E)  None of these 
A)  Viroids acting as a template for the synthesis of the prion proteins 
B)  Aberrant forms of mammalian cellular proteins that convert more mammalian cellular proteins to aberrant forms, leading to a clumping of the proteins, eventually killing the cell. 
C)  Prions converting viroids into abberant proteins that kill the cell 
D)  All of these 
E)  None of these

Question 10

The genetic information in most organisms,excluding viruses,viroids,and prions,is encoded in what molecule?

Accepted Answer

A) RNA 
B)  Protein 
C)  DNA 
D)  Lactose 
E)  Lactase 
A) RNA 
B)  Protein 
C)  DNA 
D)  Lactose 
E)  Lactase

Question 11

Which of the following is not accurate according to Chargaff's rules?

Accepted Answer

A)  A = T 
B)  C = G 
C)  A+T = C+ G 
D)  A+G = C + T 
E)  Purines = Pyrimidines 
A)  A = T 
B)  C = G 
C)  A+T = C+ G 
D)  A+G = C + T 
E)  Purines = Pyrimidines

Question 12

DNA migrates toward which pole during gel electrophoresis?

Accepted Answer

A)  Positive because DNA is negatively charged 
B)  Negative because DNA is positively charged 
C)  Positive because DNA is positively charged 
D)  Negative because DNA is negatively charged 
E)  Neither positive and negative because DNA is neutral in charge 
A)  Positive because DNA is negatively charged 
B)  Negative because DNA is positively charged 
C)  Positive because DNA is positively charged 
D)  Negative because DNA is negatively charged 
E)  Neither positive and negative because DNA is neutral in charge

Question 13

The first direct evidence indicating that DNA,rather than RNA or protein,is the genetic material in bacteria was gathered by:

Accepted Answer

A)  Griffith 
B)  Avery, McLeod, and McCarty 
C)  Hershey and Chase 
D)  Watson and Crick 
E)  Sia and Dawson 
A)  Griffith 
B)  Avery, McLeod, and McCarty 
C)  Hershey and Chase 
D)  Watson and Crick 
E)  Sia and Dawson

Question 14

The first direct evidence indicating that DNA,rather than RNA or protein,is the genetic material in bacteriophages was performed by:

Accepted Answer

A)  Griffith 
B)  Avery, McLeod, and McCarty 
C)  Hershey and Chase 
D)  Watson and Crick 
E)  Sia and Dawson 
A)  Griffith 
B)  Avery, McLeod, and McCarty 
C)  Hershey and Chase 
D)  Watson and Crick 
E)  Sia and Dawson

Question 15

Which of the following is true regarding the structure of RNA?

Accepted Answer

A)  Double stranded molecule 
B)  Single stranded molecule 
C)  Composed of nucleotides 
D)  Double stranded molecule and Composed of nucleotides 
E)  Single stranded molecule and Composed of nucleotides 
A)  Double stranded molecule 
B)  Single stranded molecule 
C)  Composed of nucleotides 
D)  Double stranded molecule and Composed of nucleotides 
E)  Single stranded molecule and Composed of nucleotides

Question 16

Three levels of condensation are required to package metaphase chromosomes.In order of complexity,lowest to highest,they are:

Accepted Answer

A)  Supercoiling into nucleosomes, chromatin fiber condensation, scaffold formation 
B)  Chromatin fiber condensation, supercoiling into nucleosomes, scaffold formation 
C)  Scaffold formation, supercoiling into nucleosomes, chromatin fiber condensation 
D)  Supercoiling into nucleosomes, scaffold formation, chromatin fiber condensation 
E)  Scaffold formation, chromatin fiber condensation, supercoiling into nucleosomes 
A)  Supercoiling into nucleosomes, chromatin fiber condensation, scaffold formation 
B)  Chromatin fiber condensation, supercoiling into nucleosomes, scaffold formation 
C)  Scaffold formation, supercoiling into nucleosomes, chromatin fiber condensation 
D)  Supercoiling into nucleosomes, scaffold formation, chromatin fiber condensation 
E)  Scaffold formation, chromatin fiber condensation, supercoiling into nucleosomes

Question 17

How does pulsed field gel electrophoresis differ from standard gel electrophoresis?

Accepted Answer

Pulsed-field gel electrophoresis,which i

Question 18

What kind of data on DNA structure was gathered by Rosalind Franklin and Maurice Wilkins?

Accepted Answer

A)  3D model 
B)  Base composition data 
C)  X-ray diffraction pattern data 
D)  All of these 
E)  None of these 
A)  3D model 
B)  Base composition data 
C)  X-ray diffraction pattern data 
D)  All of these 
E)  None of these

Question 19

Which type of chemical bond connects nitrogenous bases to each other in the center of a DNA molecule?

Accepted Answer

A)  Hydrogen 
B)  Phosphodiester 
C)  Peptide 
D)  Ionic 
E)  Covalent 
A)  Hydrogen 
B)  Phosphodiester 
C)  Peptide 
D)  Ionic 
E)  Covalent

Question 20

After Griffiths 1928 experiments leading to the discovery of the Transforming Principle,subsequent experimentation demonstrated that:

Accepted Answer

A)  The transforming principle could not be carried out in vitro 
B)  The conversion of Type IIIR to Type IIIS was due to mutation 
C)  The process of heat-killing cells was not entirely effective. 
D)  DNAse treatment eliminates all transforming activity 
E)  RNAse treatment eliminates all transforming activity 
A)  The transforming principle could not be carried out in vitro 
B)  The conversion of Type IIIR to Type IIIS was due to mutation 
C)  The process of heat-killing cells was not entirely effective. 
D)  DNAse treatment eliminates all transforming activity 
E)  RNAse treatment eliminates all transforming activity

Exam 9: DNA And The Molecular Structure Of Chromosomes

Which of the following is a phenotypic function that genetic material must be able to perform?

Which of the following is a genotypic function that the genetic material must be able to perform?

Which large organic molecules are essential chromosome components?

A single strand of a double-stranded helix has the sequence 5'-GTTTAACGTAT-3'.If the helix was in B-form,how many turns (360 degrees)would the helix make?

Compare the structure of DNA to the structure of RNA.Include at least three differences.

What were the two major pieces of evidence that led to the deduction of DNA structure by Watson and Crick and who supplied this information?

Which type of chemical bond attaches deoxyribose molecules together to form the backbone of a DNA molecule?

Which of the following statements concerning the various forms of DNA is incorrect?

The pathogenic effects of prions are thought to result from:

The genetic information in most organisms,excluding viruses,viroids,and prions,is encoded in what molecule?

Which of the following is not accurate according to Chargaff's rules?

DNA migrates toward which pole during gel electrophoresis?

The first direct evidence indicating that DNA,rather than RNA or protein,is the genetic material in bacteria was gathered by:

The first direct evidence indicating that DNA,rather than RNA or protein,is the genetic material in bacteriophages was performed by:

Which of the following is true regarding the structure of RNA?

Three levels of condensation are required to package metaphase chromosomes.In order of complexity,lowest to highest,they are:

How does pulsed field gel electrophoresis differ from standard gel electrophoresis?

What kind of data on DNA structure was gathered by Rosalind Franklin and Maurice Wilkins?

Which type of chemical bond connects nitrogenous bases to each other in the center of a DNA molecule?

After Griffiths 1928 experiments leading to the discovery of the Transforming Principle,subsequent experimentation demonstrated that:

The Science Of Genetics

Cellular Reproduction

Mendelism The Basic Principles Of Inheritance

Extensions Of Mendelism

The Chromosomal Basis Of Mendelism

Variation In Chromosome Number And Structure

Linkage,Crossing Over,And Chromosome Mapping In …

The Genetics Of Bacteria And Their Viruses

Replication Of DNA And Chromosomes

Transcription And RNA Processing

Translation And The Genetic Code

Mutation,DNA Repair,And Recombination

The Techniques Of Molecular Genetics

Genomics

Applications Of Molecular Genetics

Transposable Genetics Elements

Regulation Of Gene Expression In Prokaryotes

Regulation Of Gene Expression In Eukaryotes

The Genetic Control Of Animal Development

The Genetic Basis Of Cancer

Inheritance Of Complex Traits

Population Genetics

Evolutionary Genetics

Filters