Exam 16: Reproductive Technology - Genetic Testing - and Gene Therapy

In exon skipping,____________________ are used to target specific exons for skipping by blocking splicing signals during pre-mRNA processing.

Gene doping is an approved and widely accepted training technique for elite athletes.

Zygote intrafallopian transfer (ZIFT)requires in vitro fertilization to be performed before embryo transfer into the oviduct.

____________________ involves the fertilization of the egg outside the body,followed by transfer of the embryo into a woman's uterus.

____________________ is the recommended ART procedure performed on women with blocked oviducts.

Primary infertility is diagnosed when a couple who has had one child has trouble conceiving a second.

_____ is performed to detect genetic disorders and birth defects in a fetus.

Gene therapy has not yet cured any patient of his or her genetic disorder.

A decreased risk of epigenetic imprinting disorders,such as Beckwith-Wiedemann syndrome,is observed in children conceived following ART.

A variation of the PGD method,called ____________________,can test for genetic disorders in the egg before fertilization.

The genetic engineering of human-animal hybrids is a routine procedure related to assisted reproductive technologies.

List the three factors required for gene therapy,and explain the difference between ex vivo and in vivo gene therapy.

Early failures of gene therapy included two children who developed ____________________ after receiving gene therapy for X-linked SCID.

Cystic fibrosis is a genetic disorder that results in mucus build-up in the lungs and subsequent breathing difficulties; therefore,____________________ cells would be the target for somatic gene therapy to cure this condition.

Fertilization take place within a woman's body in which of the following ART techniques?

Discuss the ethical issues - both for and against - associated with PGD selection of savior babies.

Explain why infertility in women increases with advancing age,and how ART methods can overcome this problem in older women.

Babies who are born following PGD to select for a tissue match to an ailing sibling are referred to as ____________________.

If a male produces healthy gametes but his female partner can neither produce gametes nor carry a fetus,a(n)____________________ surrogate can be used to help them achieve successful reproduction.

The laws related to sperm donation and surrogacy are the same in each state in the US.