Exam 15: Genomes and Genomics

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Historically,inheritance of _____ was used to study the genome organization,as well as biological processes such as metabolism and development.

(Multiple Choice)
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DNA sequences comprising open reading frames (ORFs)correspond to the coding regions of genes called ____________________.

(Short Answer)
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Some people are unable to properly metabolize the drug Purinethol,which is given to patients with acute lymphoblastic leukemia; therefore,such patients must be first tested for the associated genetic variant to determine proper dosage of the drug. This scenario best illustrates the use of _____.

(Multiple Choice)
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Approximately what percentage of the human genome encodes proteins?

(Multiple Choice)
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The Ethical,Legal,and Social Issues program seeks to deal with issues related to privacy,fairness,discrimination,and reproductive decisions that emerge due to the availability of genomic information.

(True/False)
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The field of ____________________ investigates similarities and differences in the genomes from different species.

(Short Answer)
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In 2005,professional basketball player Eddy Curry was traded by the Chicago Bulls to the New York Knicks for refusing to submit to a DNA test associated with a cardiac condition.If this had occurred after 2008,the ____ may have protected him from losing his position with the Bulls.

(Multiple Choice)
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Positional cloning is used to link the inheritance of a disease in a pedigree to the inheritance of _____.

(Multiple Choice)
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One goal of the Human Genome Project was to sequence the ____________________ (number of)chromosomes in the human genome,including all autosomes and the sex chromosomes.

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One goal of proteomics research is to identify proteins that could be targets for new drugs.

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Individuals suffering from Crohn disease or irritable bowel syndrome may benefit from ____________________.

(Short Answer)
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Distances on genetic maps are measured in ____________________ and distances on physical maps are measured in ____________________.

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When Louis Kunkel discovered the gene associated with Duchenne's Muscular Dystrophy in the 1980s,he then needed to determine _____.

(Multiple Choice)
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Data gained from the Human Microbiome Project could help scientists understand _____.

(Multiple Choice)
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According to data from the Human Genome Project,98.9% of the human genome is composed of ____________________ DNA sequences.

(Short Answer)
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The genes associated with color blindness and hemophilia are located on the X chromosome. If the recombination frequency between these genes is 25%,what is the genetic map distance between them? Explain how you arrived at your answer,and why calculating recombination frequencies are an important step in creating genetic maps.

(Essay)
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The goal of pharmacogenomics is to identify genes related to human diseases.

(True/False)
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A branch of genomics that generates three-dimensional structures from their amino acid sequences is known as _____.

(Multiple Choice)
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Which of the following sequences indicates the promoter region of a gene?

(Multiple Choice)
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There are _____ microbial cells living on and in our bodies compared to the number of our body cells.

(Multiple Choice)
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