Exam 11: Genome Alterations - Mutation and Epigenetics

When ____ is incorporated into DNA or RNA during synthesis,it will create a(n)____.

Summarize some factors known to influence mutation rates of genes.

People with cystic fibrosis display a single phenotype for the disorder.

Tris-BP was banned after the discovery that the chemical caused cancer in test animals and was ____________________ through the ____________________ by those wearing treated clothing.

In sickle cell anemia,affected individuals carry ____.

Summarize the arguments both for and against irradiating foods.

Nonsense mutations change termination codons into amino acid codons.

When the number of trinucleotide repeats in a gene is significantly above normal,it can produce a mutant phenotype.

Most often,radiation doses are expressed in terms of damage.

Distinguish between sense and nonsense mutations and describe the characteristics of a protein affected by each type of mutation.

A mutation of an autosomal recessive trait can remain undetected for generations.

A form of mutation associated with the expansion in copy number of a nucleotide triplet in or near a gene is called a(n)____________________.

Several genetic disorders,including Fanconi anemia and ataxia telangiectasia,are caused by mutations in ____.

Explain what might occur when purine or pyrimidine bases in nucleotides undergo tautomeric shifts.

Beckwith-Wiedemann syndrome results from abnormalities of ____________________.

Mutagenic chemicals that ____ and are incorporated into DNA or RNA during synthesis are called base analogs.

PBDEs have not been linked directly to cancer in test animals.

The ability of DNA polymerase to repair its own nucleotide mismatches is called ____________________.

____________________ are mutations involving the increase of the number of repeat sequences in genes.

Nucleotide substitutions are mutations that alter the ____________________,but not the ____________________,of nucleotides in a DNA molecule.