Exam 4: Pedigree Analysis in Human Genetics

Draw and label a pedigree of Noah and his parents based on the theory that he was affected with an autosomal recessive genetic disorder.Explain your drawing and briefly describe the disorder that Noah might have had.

The phenotype in homozygous dominant individuals affected with an autosomal genetic disorder is often more severe than the ____________________ phenotype.

Define the term hemizygous and explain how the hemizygous condition relates to sex-linked inheritance.

If a man expresses an X-linked recessive trait,____.

Mucus production that blocks ducts of certain glands and lung passages is a symptom of ____________________.

Human traits are controlled only by the genetic material found in the 46 chromosomes.

Choose one of the basic patterns of Mendelian inheritance and draw and explain a three-generation family pedigree illustrating that pattern.

Mitochondria are transmitted from mothers to ____.

If two phenotypically normal parents have six children,and two daughters and two sons have the same genetic disorder,that disorder is most likely to be ____.

One goal of pedigree analysis is to determine ____.

Y-linked traits are ____.

If an autosomal ____________________ allele is very common in a population,there is a chance that it will enter the pedigree from outside the family.

Define the terms penetrance and expressivity and explain how they affect the expression of single gene traits.

Color blindness is an inherited disorder passed from ____________________ to child.

The phenotype of ____ does not develop until adulthood.

Czar Nicholas II of Russia and Queen Victoria's granddaughter,Alix,were the parents of a son with the genetic disorder affecting the mechanism of blood clotting called ____________________.

Summarize the arguments,both for and against,for the hypothesis that Abraham Lincoln had Marfan syndrome.

Almost all cases of cystic fibrosis,a(n)____ genetic disorder,are the result of mating between two unaffected parents.

There are ____ basic patterns of Mendelian inheritance.

Hemophilia is characterized by ____.