Question 1

microRNAs play a key role in which of the following?

Accepted Answer

A) translational repression 
B) viral RNA degradation 
C) RNA interference 
D) all of the above 
A) translational repression 
B) viral RNA degradation 
C) RNA interference 
D) all of the above

Question 2

You are using a variety of techniques to study how the RISC complex differs between siRNAs and miRNAs and have found that what distinguishes an RISC complex containing an siRNA from one containing an miRNA is that:

Accepted Answer

A) the miRNA base-pairs perfectly with its target mRNA. 
B) the siRNA base-pairs perfectly with its target mRNA. 
C) the miRNA-RISC complex inhibits transcription. 
D) the siRNA-RISC complex blocks translation. 
A) the miRNA base-pairs perfectly with its target mRNA. 
B) the siRNA base-pairs perfectly with its target mRNA. 
C) the miRNA-RISC complex inhibits transcription. 
D) the siRNA-RISC complex blocks translation.

Question 3

Sex-lethal protein in Drosophila can best be described as a(n)

Accepted Answer

A) splicing regulatory factor. 
B) RNA editing factor. 
C) transcription factor. 
D) all of the above 
A) splicing regulatory factor. 
B) RNA editing factor. 
C) transcription factor. 
D) all of the above

Question 4

Mutations that affect the binding of an SR protein to an exonic splicing enhancer can cause exon skipping in some genes,producing mRNAs that when translated yield nonfunctional proteins.In addition to an RNA-binding domain,SR proteins also contain an RS domain that is involved in binding:

Accepted Answer

A) DNA. 
B) RNA. 
C) protein. 
D) none of the above 
A) DNA. 
B) RNA. 
C) protein. 
D) none of the above

Question 5

The RISC complex contains which one of the following proteins?

Accepted Answer

A) Argonaute 
B) DGCR8 
C) Dicer 
D) Drosha 
A) Argonaute 
B) DGCR8 
C) Dicer 
D) Drosha

Question 6

How is the 5´ cap added to nascent RNAs?

Accepted Answer

A capping enzyme removes the γ-phosphate

Question 7

Synthesis of pre-rRNA occurs in the

Accepted Answer

A) nucleolus. 
B) endoplasmic reticulum. 
C) extranucleolar area of the nucleus. 
D) cytosol. 
A) nucleolus. 
B) endoplasmic reticulum. 
C) extranucleolar area of the nucleus. 
D) cytosol.

Question 8

Histone mRNAs lack

Accepted Answer

A) poly(
A) tails. 
B) introns. 
C) a 3´UTR. 
D) all of the above 
A) poly(
A) tails. 
B) introns. 
C) a 3´UTR. 
D) all of the above

Question 9

What are hnRNP proteins? How were they identified?

Accepted Answer

hnRNP proteins are the major protein com

microRNAs play a key role in which of the following?

You are using a variety of techniques to study how the RISC complex differs between siRNAs and miRNAs and have found that what distinguishes an RISC complex containing an siRNA from one containing an miRNA is that:

Sex-lethal protein in Drosophila can best be described as a(n)

Mutations that affect the binding of an SR protein to an exonic splicing enhancer can cause exon skipping in some genes,producing mRNAs that when translated yield nonfunctional proteins.In addition to an RNA-binding domain,SR proteins also contain an RS domain that is involved in binding:

The RISC complex contains which one of the following proteins?

How is the 5´ cap added to nascent RNAs?

Synthesis of pre-rRNA occurs in the

Histone mRNAs lack

What are hnRNP proteins? How were they identified?

Chemical Foundations

Molecular Genetic Techniques

Protein Structure and Function

Culturing and Visualizing Cells

Fundamental Molecular Genetic Mechanisms

Bio-membrane Structure

Genes Genomics and Chromosomes

Transcriptional Control of Gene Expression

Transmembrane Transport of Ions and Small Molecules

Cellular Energetics

Moving Proteins Into Membranes and Organelles

Vesicular Traffic, Secretion, and Endocytosis

Signal Transduction and G-Protein Coupled Receptors

Signaling Pathways That Control Gene Activity

Cell Organization and Movement I: Microfilaments

Cell Organization and Movement II: Microtubules and Intermediate Filaments

Regulating the Eukaryotic Cell Cycle

Integrating Cells Into Tissues

Cell Birth, Lineage, and Death

Nerve Cells

Immunology

Cancer

Filters

Exam 9: Post-Transcriptional Gene Control

microRNAs play a key role in which of the following?

You are using a variety of techniques to study how the RISC complex differs between siRNAs and miRNAs and have found that what distinguishes an RISC complex containing an siRNA from one containing an miRNA is that:

Sex-lethal protein in Drosophila can best be described as a(n)

Mutations that affect the binding of an SR protein to an exonic splicing enhancer can cause exon skipping in some genes,producing mRNAs that when translated yield nonfunctional proteins.In addition to an RNA-binding domain,SR proteins also contain an RS domain that is involved in binding:

The RISC complex contains which one of the following proteins?

How is the 5´ cap added to nascent RNAs?

Synthesis of pre-rRNA occurs in the

Histone mRNAs lack

What are hnRNP proteins? How were they identified?

Chemical Foundations

Molecular Genetic Techniques

Protein Structure and Function

Culturing and Visualizing Cells

Fundamental Molecular Genetic Mechanisms

Bio-membrane Structure

Genes Genomics and Chromosomes

Transcriptional Control of Gene Expression

Transmembrane Transport of Ions and Small Molecules

Cellular Energetics

Moving Proteins Into Membranes and Organelles

Vesicular Traffic, Secretion, and Endocytosis

Signal Transduction and G-Protein Coupled Receptors

Signaling Pathways That Control Gene Activity

Cell Organization and Movement I: Microfilaments

Cell Organization and Movement II: Microtubules and Intermediate Filaments

Regulating the Eukaryotic Cell Cycle

Integrating Cells Into Tissues

Cell Birth, Lineage, and Death

Nerve Cells

Immunology

Cancer

Filters