Question 1

Cyclic neutropenia is so named because this condition

Accepted Answer

A)  has more than one inheritance pattern. 
B)  has environmental factors that participate in its cause. 
C)  displays a decrease in the number of neutrophils that occur in cycles of 21 to 27 days. 
D)  allows persons to carry a gene with a dominant effect without any clinical manifestations. 
A)  has more than one inheritance pattern. 
B)  has environmental factors that participate in its cause. 
C)  displays a decrease in the number of neutrophils that occur in cycles of 21 to 27 days. 
D)  allows persons to carry a gene with a dominant effect without any clinical manifestations.

Question 2

Multiple osteomas and odontomas seen with Gardner syndrome can cause which oral complication?

Accepted Answer

A)  Teeth fail to erupt. 
B)  Teeth demonstrate increased mobility. 
C)  Increased supernumerary teeth 
D)  Teeth exfoliate prematurely. 
A)  Teeth fail to erupt. 
B)  Teeth demonstrate increased mobility. 
C)  Increased supernumerary teeth 
D)  Teeth exfoliate prematurely.

Question 3

Which statement is true of oogenesis?

Accepted Answer

A)  Oogenesis starts around the time of puberty. 
B)  The second meiosis is completed at the beginning of ovulation. 
C)  Nondisjunction is more prevalent in male spermatogenesis than in female oogenesis. 
D)  The older the woman, the greater the chance of shedding a trisomic ovum. 
A)  Oogenesis starts around the time of puberty. 
B)  The second meiosis is completed at the beginning of ovulation. 
C)  Nondisjunction is more prevalent in male spermatogenesis than in female oogenesis. 
D)  The older the woman, the greater the chance of shedding a trisomic ovum.

Question 4

For each genetic definition below, select the corresponding genetic term from the list provided.
-Position occupied by a gene on a chromosome

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

Question 5

Primitive germ cells have _____ chromosomes and are termed _____.

Accepted Answer

A)  23; diploid 
B)  46; haploid 
C)  23; haploid 
D)  46; diploid 
A)  23; diploid 
B)  46; haploid 
C)  23; haploid 
D)  46; diploid

Question 6

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in

Accepted Answer

A)  lack of otic ossicles. 
B)  unilateral or bilateral aplasia or hypoplasia of clavicles. 
C)  overgrowth of cortical bone in the midline of the palate. 
D)  abnormally formed bones that fracture easily. 
A)  lack of otic ossicles. 
B)  unilateral or bilateral aplasia or hypoplasia of clavicles. 
C)  overgrowth of cortical bone in the midline of the palate. 
D)  abnormally formed bones that fracture easily.

Question 7

During meiosis, if chromosomes crossing over do not separate and both migrate to the same cell, a germ cell with an extra chromosome results. What is the term to describe this occurrence?

Accepted Answer

A)  Nondisjunction 
B)  Chiasmata 
C)  Translation 
D)  Alleles 
A)  Nondisjunction 
B)  Chiasmata 
C)  Translation 
D)  Alleles

Question 8

Which syndrome is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Accepted Answer

A)  Osler-Rendu-Parkes Weber syndrome 
B)  Van der Woude syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome 
A)  Osler-Rendu-Parkes Weber syndrome 
B)  Van der Woude syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome

Question 9

Hypophosphatasia is characterized by

Accepted Answer

A)  an increase in serum alkaline phosphatase levels. 
B)  abnormal formation of enamel and dentin. 
C)  exfoliation of teeth without evidence of periodontal or gingival disease. 
D)  an autosomal-dominant inheritance pattern. 
A)  an increase in serum alkaline phosphatase levels. 
B)  abnormal formation of enamel and dentin. 
C)  exfoliation of teeth without evidence of periodontal or gingival disease. 
D)  an autosomal-dominant inheritance pattern.

Question 10

Which clinical syndrome caused by gross chromosomal abnormalities is associated with bilateral cleft lip and palate, microphthalmia or anophthalmia, and polydactyly?

Accepted Answer

A)  Trisomy 13 
B)  Trisomy 21 
C)  Turner syndrome 
D)  Klinefelter syndrome 
A)  Trisomy 13 
B)  Trisomy 21 
C)  Turner syndrome 
D)  Klinefelter syndrome

Question 11

The gap 2 (G2) phase of mitosis

Accepted Answer

A)  begins when mitotic division ends. 
B)  ends when mitotic division begins. 
C)  precedes the S phase. 
D)  is when replication of DNA takes place. 
A)  begins when mitotic division ends. 
B)  ends when mitotic division begins. 
C)  precedes the S phase. 
D)  is when replication of DNA takes place.

Question 12

A patient with Ellis-van Creveld syndrome will

Accepted Answer

A)  show polydactyly on the radial side of the forearm. 
B)  be a little person. 
C)  lack an anterior maxillary vestibular sulcus. 
D)  lack a posterior mandibular sulcus. 
A)  show polydactyly on the radial side of the forearm. 
B)  be a little person. 
C)  lack an anterior maxillary vestibular sulcus. 
D)  lack a posterior mandibular sulcus.

Question 13

A man's X chromosome is transmitted to _____ of his daughters and _____ of his sons.

Accepted Answer

A)  none; none 
B)  none; all 
C)  all; none 
D)  all; all 
A)  none; none 
B)  none; all 
C)  all; none 
D)  all; all

Question 14

Intestinal polyps seen with Peutz-Jeghers syndrome are

Accepted Answer

A)  associated with inevitable malignant transformation into adenocarcinomas. 
B)  hamartomas. 
C)  caused by the adenomatous polyposis coli (AP
C)  gene located on the long arm of chromosome 5. 
D)  associated with osteomas in various bones, especially the frontal bones, mandible, and maxilla. 
A)  associated with inevitable malignant transformation into adenocarcinomas. 
B)  hamartomas. 
C)  caused by the adenomatous polyposis coli (AP
C)  gene located on the long arm of chromosome 5. 
D)  associated with osteomas in various bones, especially the frontal bones, mandible, and maxilla.

Question 15

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.
-Cri du chat

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 16

Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Accepted Answer

A)  alteration in the structure 
B)  abnormal rearrangement 
C)  alteration in the number 
D)  duplication 
A)  alteration in the structure 
B)  abnormal rearrangement 
C)  alteration in the number 
D)  duplication

Question 17

Oral manifestations of nevoid basal cell carcinoma syndrome consist of multiple cysts of the jaws that are

Accepted Answer

A)  central giant cell granulomas. 
B)  peripheral giant cell granulomas. 
C)  odontogenic keratocysts. 
D)  calcifying epithelial odontogenic tumors. 
A)  central giant cell granulomas. 
B)  peripheral giant cell granulomas. 
C)  odontogenic keratocysts. 
D)  calcifying epithelial odontogenic tumors.

Question 18

Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and

Accepted Answer

A)  telangiectases. 
B)  pheochromocytoma. 
C)  gastrointestinal polyposis. 
D)  blue sclera. 
A)  telangiectases. 
B)  pheochromocytoma. 
C)  gastrointestinal polyposis. 
D)  blue sclera.

Question 19

Identify the term that describes a mating or marriage between close relatives:

Accepted Answer

A)  Chiasmata 
B)  Consanguinity 
C)  Trisomy 
D)  Translocation 
A)  Chiasmata 
B)  Consanguinity 
C)  Trisomy 
D)  Translocation

Question 20

_________ is a consistent feature of mandibulofacial dysostosis.

Accepted Answer

A)  Hypertrichosis 
B)  Deafness 
C)  Hypertelorism 
D)  Kyphoscoliosis 
A)  Hypertrichosis 
B)  Deafness 
C)  Hypertelorism 
D)  Kyphoscoliosis

Cyclic neutropenia is so named because this condition

Multiple osteomas and odontomas seen with Gardner syndrome can cause which oral complication?

Which statement is true of oogenesis?

For each genetic definition below, select the corresponding genetic term from the list provided. -Position occupied by a gene on a chromosome

Primitive germ cells have _ chromosomes and are termed _.

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in

During meiosis, if chromosomes crossing over do not separate and both migrate to the same cell, a germ cell with an extra chromosome results. What is the term to describe this occurrence?

Which syndrome is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Hypophosphatasia is characterized by

Which clinical syndrome caused by gross chromosomal abnormalities is associated with bilateral cleft lip and palate, microphthalmia or anophthalmia, and polydactyly?

The gap 2 (G₂) phase of mitosis

A patient with Ellis-van Creveld syndrome will

A man's X chromosome is transmitted to _ of his daughters and _ of his sons.

Intestinal polyps seen with Peutz-Jeghers syndrome are

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Cri du chat

Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Oral manifestations of nevoid basal cell carcinoma syndrome consist of multiple cysts of the jaws that are

Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and

Identify the term that describes a mating or marriage between close relatives:

_________ is a consistent feature of mandibulofacial dysostosis.

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

Cyclic neutropenia is so named because this condition

Multiple osteomas and odontomas seen with Gardner syndrome can cause which oral complication?

Which statement is true of oogenesis?

For each genetic definition below, select the corresponding genetic term from the list provided. -Position occupied by a gene on a chromosome

Primitive germ cells have _____ chromosomes and are termed _____.

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in

During meiosis, if chromosomes crossing over do not separate and both migrate to the same cell, a germ cell with an extra chromosome results. What is the term to describe this occurrence?

Which syndrome is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Hypophosphatasia is characterized by

Which clinical syndrome caused by gross chromosomal abnormalities is associated with bilateral cleft lip and palate, microphthalmia or anophthalmia, and polydactyly?

The gap 2 (G2) phase of mitosis

A patient with Ellis-van Creveld syndrome will

A man's X chromosome is transmitted to _____ of his daughters and _____ of his sons.

Intestinal polyps seen with Peutz-Jeghers syndrome are

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Cri du chat

Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Oral manifestations of nevoid basal cell carcinoma syndrome consist of multiple cysts of the jaws that are

Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and

Identify the term that describes a mating or marriage between close relatives:

_________ is a consistent feature of mandibulofacial dysostosis.

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters

Primitive germ cells have _ chromosomes and are termed _.

The gap 2 (G₂) phase of mitosis

A man's X chromosome is transmitted to _ of his daughters and _ of his sons.