Question 1

The correct order for the stages of mitosis is

Accepted Answer

A)  prophase, anaphase, metaphase, telophase. 
B)  prophase, metaphase, anaphase, telophase. 
C)  prophase, metaphase, telophase, anaphase. 
D)  metaphase, prophase, telophase, anaphase. 
A)  prophase, anaphase, metaphase, telophase. 
B)  prophase, metaphase, anaphase, telophase. 
C)  prophase, metaphase, telophase, anaphase. 
D)  metaphase, prophase, telophase, anaphase.

Question 2

The areas of bony radiolucency seen in cherubism

Accepted Answer

A)  resemble a central giant cell granuloma when seen under the microscope. 
B)  occur in place of the teeth, and radiographs will reveal complete anodontia. 
C)  will increase in size as the patient matures, even until the seventh or eighth decade of life. 
D)  will resolve, leaving the patient without any sign of facial deformity later in life. 
A)  resemble a central giant cell granuloma when seen under the microscope. 
B)  occur in place of the teeth, and radiographs will reveal complete anodontia. 
C)  will increase in size as the patient matures, even until the seventh or eighth decade of life. 
D)  will resolve, leaving the patient without any sign of facial deformity later in life.

Question 3

Gingival and periodontal disease has been reported in _____% of individuals with Down syndrome.

Accepted Answer

A)  10 
B)  25 
C)  50 
D)  90 
A)  10 
B)  25 
C)  50 
D)  90

Question 4

White sponge nevus is characterized by a white, corrugated, soft, folding oral mucosa always affecting _____ mucosa.

Accepted Answer

A)  attached 
B)  lingual 
C)  buccal 
D)  tonsillar 
A)  attached 
B)  lingual 
C)  buccal 
D)  tonsillar

Question 5

According to the Lyon hypothesis during the early period of embryonic development, the

Accepted Answer

A)  genetic activity of both of the X chromosomes in each cell of a female embryo is inactivated. 
B)  genetic activity of one of the X chromosomes in each cell of a female embryo is inactivated. 
C)  genetic activity of the Y chromosome in each cell of a male embryo is inactivated. 
D)  inactivated chromosome forms a structure known as the pronucleus. 
A)  genetic activity of both of the X chromosomes in each cell of a female embryo is inactivated. 
B)  genetic activity of one of the X chromosomes in each cell of a female embryo is inactivated. 
C)  genetic activity of the Y chromosome in each cell of a male embryo is inactivated. 
D)  inactivated chromosome forms a structure known as the pronucleus.

Question 6

Which syndrome is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Accepted Answer

A)  Osler-Rendu-Parkes Weber syndrome 
B)  Ellis-van Creveld syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome 
A)  Osler-Rendu-Parkes Weber syndrome 
B)  Ellis-van Creveld syndrome 
C)  Gorlin syndrome 
D)  Peutz-Jeghers syndrome

Question 7

Cases of facial clefting occur in about 1 in _____ births.

Accepted Answer

A)  80 
B)  200 
C)  800 
D)  2000 
A)  80 
B)  200 
C)  800 
D)  2000

Question 8

If both loci for blood are AO, the

Accepted Answer

A)  person is said to have blood group O. 
B)  person is said to have blood group A. 
C)  person would be homozygous. 
D)  characteristic is recessive. 
A)  person is said to have blood group O. 
B)  person is said to have blood group A. 
C)  person would be homozygous. 
D)  characteristic is recessive.

Question 9

A patient with Papillon-Lefèvre syndrome displays severe periodontal disease until the last tooth has been exfoliated. The skin manifestations of hyperkeratosis remain present for the life of the patient.

Accepted Answer

A)  Both statements are true. 
B)  Both statements are false. 
C)  The first statement is true; the second statement is false. 
D)  The first statement is false; the second statement is true. 
A)  Both statements are true. 
B)  Both statements are false. 
C)  The first statement is true; the second statement is false. 
D)  The first statement is false; the second statement is true.

Question 10

Early diagnosis of pheochromocytoma is imperative because of the high malignant potential of

Accepted Answer

A)  squamous cell carcinoma. 
B)  basal cell carcinoma. 
C)  thyroid carcinoma. 
D)  osteogenic sarcoma. 
A)  squamous cell carcinoma. 
B)  basal cell carcinoma. 
C)  thyroid carcinoma. 
D)  osteogenic sarcoma.

Question 11

Which is true about making a karyotype?

Accepted Answer

A)  Arginine may be used to arrest the mitosis of leukocytes at metaphase. 
B)  Colchicine may be used to arrest the mitosis of leukocytes at metaphase. 
C)  Colchicine may be used to arrest the mitosis of red blood cells at anaphase. 
D)  It is used to evaluate molecular abnormalities in chromosomes. 
A)  Arginine may be used to arrest the mitosis of leukocytes at metaphase. 
B)  Colchicine may be used to arrest the mitosis of leukocytes at metaphase. 
C)  Colchicine may be used to arrest the mitosis of red blood cells at anaphase. 
D)  It is used to evaluate molecular abnormalities in chromosomes.

Question 12

A codon in DNA is formed by a sequence of _____ bases.

Accepted Answer

A)  two 
B)  three 
C)  four 
D)  six 
A)  two 
B)  three 
C)  four 
D)  six

Question 13

Oral manifestations seen with a person with Down syndrome include the following except one. Which is the exception?

Accepted Answer

A)  Fissured tongue 
B)  Gingival and periodontal disease 
C)  Hypodontia 
D)  Macrodontia 
A)  Fissured tongue 
B)  Gingival and periodontal disease 
C)  Hypodontia 
D)  Macrodontia

Question 14

A karyotype containing XXXY indicates _____ syndrome.

Accepted Answer

A)  Down 
B)  Klinefelter 
C)  Turner 
D)  cri du chat 
A)  Down 
B)  Klinefelter 
C)  Turner 
D)  cri du chat

Question 15

For autosomal-dominant inheritance

Accepted Answer

A)  males will be affected more often than females. 
B)  the risk of having an affected offspring is 25% when a person has a gene for the condition. 
C)  all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance. 
D)  an individual can carry a gene with a dominant effect without presenting any clinical manifestations. 
A)  males will be affected more often than females. 
B)  the risk of having an affected offspring is 25% when a person has a gene for the condition. 
C)  all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance. 
D)  an individual can carry a gene with a dominant effect without presenting any clinical manifestations.

Question 16

Which type of RNA carries the message for translation of DNA to ribosomes in the cytoplasm?

Accepted Answer

A)  mRNA 
B)  tRNA 
C)  rRNA 
D)  hnRNA 
A)  mRNA 
B)  tRNA 
C)  rRNA 
D)  hnRNA

Question 17

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.
-Trisomy 21

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 18

During translation

Accepted Answer

A)  polypeptides form an amino acid, and one or more amino acids form a protein. 
B)  amino acids form a polypeptide, and one or more polypeptides form a protein. 
C)  proteins form a polypeptide, and one or more polypeptides form an amino acid. 
D)  amino acids form a protein, and one or more proteins form a polypeptide. 
A)  polypeptides form an amino acid, and one or more amino acids form a protein. 
B)  amino acids form a polypeptide, and one or more polypeptides form a protein. 
C)  proteins form a polypeptide, and one or more polypeptides form an amino acid. 
D)  amino acids form a protein, and one or more proteins form a polypeptide.

Question 19

Blood group _____ is an example of gene codominance.

Accepted Answer

A)  O 
B)  A 
C)  B 
D)  AB 
A)  O 
B)  A 
C)  B 
D)  AB

Question 20

Between the ages of 1½ and 4, what is the first clinical sign of cherubism?

Accepted Answer

A)  Cleft palate 
B)  Bilateral facial swelling 
C)  Fissured tongue 
D)  Severe mental handicap 
A)  Cleft palate 
B)  Bilateral facial swelling 
C)  Fissured tongue 
D)  Severe mental handicap

The correct order for the stages of mitosis is

The areas of bony radiolucency seen in cherubism

Gingival and periodontal disease has been reported in _____% of individuals with Down syndrome.

White sponge nevus is characterized by a white, corrugated, soft, folding oral mucosa always affecting _____ mucosa.

According to the Lyon hypothesis during the early period of embryonic development, the

Which syndrome is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Cases of facial clefting occur in about 1 in _____ births.

If both loci for blood are AO, the

A patient with Papillon-Lefèvre syndrome displays severe periodontal disease until the last tooth has been exfoliated. The skin manifestations of hyperkeratosis remain present for the life of the patient.

Early diagnosis of pheochromocytoma is imperative because of the high malignant potential of

Which is true about making a karyotype?

A codon in DNA is formed by a sequence of _____ bases.

Oral manifestations seen with a person with Down syndrome include the following except one. Which is the exception?

A karyotype containing XXXY indicates _____ syndrome.

For autosomal-dominant inheritance

Which type of RNA carries the message for translation of DNA to ribosomes in the cytoplasm?

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Trisomy 21

During translation

Blood group _____ is an example of gene codominance.

Between the ages of 1½ and 4, what is the first clinical sign of cherubism?

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

The correct order for the stages of mitosis is

The areas of bony radiolucency seen in cherubism

Gingival and periodontal disease has been reported in _____% of individuals with Down syndrome.

White sponge nevus is characterized by a white, corrugated, soft, folding oral mucosa always affecting _____ mucosa.

According to the Lyon hypothesis during the early period of embryonic development, the

Which syndrome is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Cases of facial clefting occur in about 1 in _____ births.

If both loci for blood are AO, the

A patient with Papillon-Lefèvre syndrome displays severe periodontal disease until the last tooth has been exfoliated. The skin manifestations of hyperkeratosis remain present for the life of the patient.

Early diagnosis of pheochromocytoma is imperative because of the high malignant potential of

Which is true about making a karyotype?

A codon in DNA is formed by a sequence of _____ bases.

Oral manifestations seen with a person with Down syndrome include the following except one. Which is the exception?

A karyotype containing XXXY indicates _____ syndrome.

For autosomal-dominant inheritance

Which type of RNA carries the message for translation of DNA to ribosomes in the cytoplasm?

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Trisomy 21

During translation

Blood group _____ is an example of gene codominance.

Between the ages of 1½ and 4, what is the first clinical sign of cherubism?

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Orofacial Pain and Diseases Affecting the Temporomandibular Joint

Filters