Question 1

What is the advantage of using a VNTR over SNP as a genetic marker?

Accepted Answer

A)  There are more VNTRs in the genome 
B)  VNTRs are less variable 
C)  There are generally more alleles for each VNTR than for each SNP 
D)  VNTRs are located within genes 
E)  VNTRs are more likely to be mutations rather than polymorphisms 
A)  There are more VNTRs in the genome 
B)  VNTRs are less variable 
C)  There are generally more alleles for each VNTR than for each SNP 
D)  VNTRs are located within genes 
E)  VNTRs are more likely to be mutations rather than polymorphisms C

Question 2

Why are dideoxynucleotides added to the reaction in the Sanger sequencing methodology?

Accepted Answer

A)  They label the DNA strands 
B)  They cause termination of the replicating strand 
C)  They allow longer processivity of the DNA polymerase 
D)  They cement the newly synthesized strand to the template strand 
E)  There is a lower chance of mutation during the sequencing reaction 
A)  They label the DNA strands 
B)  They cause termination of the replicating strand 
C)  They allow longer processivity of the DNA polymerase 
D)  They cement the newly synthesized strand to the template strand 
E)  There is a lower chance of mutation during the sequencing reaction B

Question 3

Which type of marker is used for DNA fingerprinting?

Accepted Answer

A)  SNP 
B)  Microsatellite 
C)  Indel 
D)  Minisatellite 
E)  Copy number variant 
A)  SNP 
B)  Microsatellite 
C)  Indel 
D)  Minisatellite 
E)  Copy number variant D

What is the advantage of using a VNTR over SNP as a genetic marker?

Why are dideoxynucleotides added to the reaction in the Sanger sequencing methodology?

Which type of marker is used for DNA fingerprinting?

The History and Impact of Genetics in Medicine

The Cellular and Molecular Basis of Inheritance

Chromosomes and Cell Division

Mapping and Identifying Genes for Monogenic Disorders

Developmental Genetics

Patterns of Inheritance

Population and Mathematical Genetics

Polygenic and Multifactorial Inheritance

Hemoglobin and the Hemoglobinopathies

Biochemical Genetics

Pharmacogenetics

Immunogenetics

Cancer Genetics

Genetic Factors in Common Diseases

Congenital Abnormalities and Dysmorphic Syndromes

Genetic Counseling

Chromosome Disorders

Single-Gene Disorders

Screening for Genetic Disease

Prenatal Testing and Reproductive Genetics

Risk Calculation

Treatment of Genetic Disease

Ethical and Legal Issues in Medical Genetics

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Exam 4: Dna Technology and Applications

What is the advantage of using a VNTR over SNP as a genetic marker?

Why are dideoxynucleotides added to the reaction in the Sanger sequencing methodology?

Which type of marker is used for DNA fingerprinting?

The History and Impact of Genetics in Medicine

The Cellular and Molecular Basis of Inheritance

Chromosomes and Cell Division

Mapping and Identifying Genes for Monogenic Disorders

Developmental Genetics

Patterns of Inheritance

Population and Mathematical Genetics

Polygenic and Multifactorial Inheritance

Hemoglobin and the Hemoglobinopathies

Biochemical Genetics

Pharmacogenetics

Immunogenetics

Cancer Genetics

Genetic Factors in Common Diseases

Congenital Abnormalities and Dysmorphic Syndromes

Genetic Counseling

Chromosome Disorders

Single-Gene Disorders

Screening for Genetic Disease

Prenatal Testing and Reproductive Genetics

Risk Calculation

Treatment of Genetic Disease

Ethical and Legal Issues in Medical Genetics

Filters