Exam 24: Neurogenetics

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Why is cyclic AMP considered important in behavioral studies?

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One of the oldest recorded behavior mutants is the waltzer mutation in the mouse.Mutant mice can be observed "dancing" and "head shaking"; some are also deaf.Mice must be homozygous for a mutation to express the trait.Based on this information,the genetic cause of this trait is most likely a(n)________.

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Huntington disease (HD)is a well-studied,autosomal dominant disorder that affects the nervous system.Symptoms usually appear after age 40,and victims usually die within 10 to 15 years after onset of the disease.It appears that at least in some cases of HD,"stutter" mutations occur.Such mutations are characterized by ________.

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Research on alcoholism indicates that at least in mouse and animal models,a single dominant gene is responsible.

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Determining the genetic influence on two fairly common human behavioral disorders has eluded researchers for many years.One involves passive deficits in thinking,language,feelings,and social skills; the other includes a variety of psychotic symptoms,perceptual disorders (hearing voices),and withdrawal from reality.Evidence from pedigrees and twins indicates that these two behaviors have a genetic component.Which behaviors are being described here?

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What anatomical structure is responsible for the transfer of impulses between neurons?

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The availability of a large series of monozygotic and dizygotic twins often enhances studies on the genetic basis of human behavior.

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What is a major problem that arises in the study of the genetic basis of human behavior?

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What conclusion has been reached regarding the genetic status of schizophrenia using genome-wide association studies?

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