Exam 14: Translation and Proteins

Different domains in proteins impart different functional capabilities.

When a metabolic block occurs in a biochemical pathway,it is common for amount of the substance immediately prior to that block to increase.

A short segment of an mRNA molecule is shown below.The polypeptide it codes for is also shown: 5′-AUGGUGCUGAAG-3′: methionine-valine-leucine-lysine Assume that a mutation in the DNA occurs so that the fourth base (counting from the 5′ end)of the messenger RNA now reads A rather than G.What sequence of amino acids will the mRNA now code for? (You do not need a copy of the genetic code to answer the question.)

Draw and label the spatial and polarity relationships among the following translational components: ribosome (small and large subunits),growing polypeptide chains,amino acid attachment to tRNA,mRNA,codon,and anticodon.

Knowing that the base sequence of any given messenger RNA is responsible for precisely ordering the amino acids in a respective protein,present two mechanisms by which intrinsic properties of mRNA may regulate the "net output" of a given gene.

Describe each of the following parameters that relate to the structure and function of tRNA: (a) four functional domains (b) Wobble hypothesis

Which class of protein functions primarily by lowering the energy of activation during a reaction?

Electrophoretic separation of HbA from HbS is based on a difference in their ________.

By their experimentation using the Neurospora fungus,Beadle and Tatum were able to propose the far-reaching hypothesis that ________.

Side groups of amino acids are typically classified under which of the following?