Exam 13: Chromosome Aberrations and Transposition

A chromosome has broken,and a piece of one chromosome is translocated to a nonhomologous chromosome.This is an example of what type of chromosomal alteration?

A region of a chromosome on spanning the centromere is broken and reattached in the reverse direction.This is an example of which type of chromosomal defect?

AluI is an example of which type of transposable element commonly found in the genome of humans?

Which type of chromosome deletions is caused by two concurrent chromosome breaks (rather than a single break)?

If you wish to target a retrovirus in a cell but do not want to disrupt retrotransposons,which gene(s)would you target?

When nondisjunction occurs early in embryogenesis rather than gametogenesis,what would you expect in the resulting karyotype?

Chromosomal translocation involves chromosome breakage and reattachment of the broken segment to a ________.

How are retroviruses and retrotransposons similar? Describe the genes encodes by the DNA of the retrovirus and the two DNA elements consistently found in retrotransposons.

P elements cause which phenomenon responsible for sterility in Drosophila?

Prader-Willi and Angelman syndromes are caused by which type of chromosomal mutations,both in connection with chromosome 15?

In balanced translocation heterozygotes,which pattern of chromosome segregation produces viable gamets and progeny?

What effect does a Robertsonian translocation have on chromosome number?

________ is rare and occurs most commonly when repetitive regions of homologous chromosomes misalign,resulting in partial deletions and partial duplications.

During gametogenesis,what percentage of gametes would be trisomic if the nondisjunction event occurs during meiosis II?

The phenomenon of ________ in allopolyploids consists of more rapid growth,increased fruit and flower production,and improved disease resistance.

A chromosome contains the following gene order: A B C D • E F G H Which of the following rearrangements represents a paracentric inversion?

What two features are consistently seen within retrotransposons?

Describe two mechanisms for causing uniparental disomy,and explain how this chromosomal defect is involved in Prader-Willi syndrome and Angelman syndrome.

Which enzyme(s)is/are responsible for excising and copying transposable genetic elements from chromosomes and inserting them into new locations?

What is the name of the chromosomal region,located on region 21q22.2 that was identified by studying individuals with partial trisomy of chromosome 21?