Question 1

Use the table below to determine which template strand DNA sequence (written in the 5' → 3' direction)specifies the tripeptide with the sequence gly-ala-leu.

Accepted Answer

A) GGGGCTCTC 
B) CTCTCGGGG 
C) CCCCGAGAG 
D) GAGAGCCCC 
A) GGGGCTCTC 
B) CTCTCGGGG 
C) CCCCGAGAG 
D) GAGAGCCCC

Question 2

For each amino acid added to a polypeptide chain,________ phosphoanhydride bonds are cleaved.

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
E) 5 
A) 1 
B) 2 
C) 3 
D) 4 
E) 5

Question 3

Class II aminoacyl-tRNA synthetases are often multimeric enzymes that do not bind to the anticodon.

Accepted Answer

A) True 
 B)False

Question 4

There are five times more ribosomes in eukaryotic cells than in most bacterial cells.

Accepted Answer

A) True 
 B)False

Question 5

The 5' end and the region near the 3' end of tRNA molecules are base-paired to each other forming

Accepted Answer

A) the anticodon arm. 
B) the acceptor or amino acid stem. 
C) one arm of the three-dimensional structure. 
D) the variable arm. 
A) the anticodon arm. 
B) the acceptor or amino acid stem. 
C) one arm of the three-dimensional structure. 
D) the variable arm.

Question 6

How are the termination codons different from other codons?

Accepted Answer

A) They contain thymines. 
B) The termination codon always codes for methionine. 
C) They are not recognized by any tRNA molecules. 
D) Their conformations do not allow them to fit properly in the A site of the ribosome. 
A) They contain thymines. 
B) The termination codon always codes for methionine. 
C) They are not recognized by any tRNA molecules. 
D) Their conformations do not allow them to fit properly in the A site of the ribosome.

Question 7

Inosinate (I)is an acetylated form of G and it can base-pair with A,C,or U.

Accepted Answer

A) True 
 B)False

Question 8

Which is not true about the genetic code?

Accepted Answer

A) Some amino acids share the same codon. 
B) The first two nucleotides of a codon are often enough to specify a given amino acid. 
C) Some codons do not specify an amino acid. 
D) Nearly all organisms use the same genetic code. 
A) Some amino acids share the same codon. 
B) The first two nucleotides of a codon are often enough to specify a given amino acid. 
C) Some codons do not specify an amino acid. 
D) Nearly all organisms use the same genetic code.

Question 9

What provides most of the energy needed for protein synthesis?

Accepted Answer

A) Breakage of phosphate ester bonds. 
B) Breakage of phosphoanhydride bonds. 
C) Formation of phosphate ester bonds. 
D) Formation of phosphoanhydride bonds. 
E) Formation of peptide bonds. 
A) Breakage of phosphate ester bonds. 
B) Breakage of phosphoanhydride bonds. 
C) Formation of phosphate ester bonds. 
D) Formation of phosphoanhydride bonds. 
E) Formation of peptide bonds.

Question 10

Peptidyl transferase catalyzes peptide bond formation,and the activity is contained within the protein portion of the large ribosomal subunit.

Accepted Answer

A) True 
 B)False

Question 11

Tryptophan synthesis can be controlled by a process called attenuation in which the levels of tryptophan in the cell control translation by

Accepted Answer

A) the binding of the RNA polymerase to the genome. 
B) the alteration of the repressor protein. 
C) the folding of mRNA into hairpin loops. 
D) genes rich in codons for tryptophan. 
A) the binding of the RNA polymerase to the genome. 
B) the alteration of the repressor protein. 
C) the folding of mRNA into hairpin loops. 
D) genes rich in codons for tryptophan.

Question 12

The processing of ribosomal RNA precursors includes binding of six or seven ribosomal proteins before assembly of the ribosome begins.

Accepted Answer

A) True 
 B)False

Question 13

The main control of the rate of globin synthesis is due to the activity of GEF (guanine nucleotide exchange factor).

Accepted Answer

A) True 
 B)False

Question 14

Which statement is false concerning ribosomes and their components?

Accepted Answer

A) All ribosomes have two subunits of unequal size. 
B) The genes for eukaryotic rRNA occur as tandem arrays of hundreds of copies. 
C) The 30S and 50S ribosomal subunits of E.coli combine to generate an 80S subunit. 
D) Sequences exist in prokaryotic and eukaryotic rRNA that are so similar,they likely derive from a common ancestor. 
A) All ribosomes have two subunits of unequal size. 
B) The genes for eukaryotic rRNA occur as tandem arrays of hundreds of copies. 
C) The 30S and 50S ribosomal subunits of E.coli combine to generate an 80S subunit. 
D) Sequences exist in prokaryotic and eukaryotic rRNA that are so similar,they likely derive from a common ancestor.

Question 15

Of all the possible triplet codons,________ do not code for an amino acid.

Accepted Answer

A) 0 
B) 1 
C) 2 
D) 3 
E) 4 
A) 0 
B) 1 
C) 2 
D) 3 
E) 4

Question 16

How many possible codons (of normal size)are possible using the bases found in DNA?

Accepted Answer

A) 4 
B) 16 
C) 20 
D) 64 
A) 4 
B) 16 
C) 20 
D) 64

Question 17

EF-Ts promotes the dissociation of GDP from the EF-Tu-GDP complex to recycle this elongation factor.

Accepted Answer

A) True 
 B)False

Question 18

The reading frame of DNA is fixed by

Accepted Answer

A) mRNA. 
B) the initiation codon. 
C) one of three stop codons. 
D) the codon UUU. 
A) mRNA. 
B) the initiation codon. 
C) one of three stop codons. 
D) the codon UUU.

Question 19

Which statement is false concerning aminoacyl-tRNA synthetase?

Accepted Answer

A) It recognizes only one amino acid,but may recognize more than one tRNA. 
B) It requires a conversion from ATP to ADP. 
C) Hydrolysis of pyrophosphate essentially makes its reaction irreversible. 
D) Some synthetases bind the anticodon and others do not. 
A) It recognizes only one amino acid,but may recognize more than one tRNA. 
B) It requires a conversion from ATP to ADP. 
C) Hydrolysis of pyrophosphate essentially makes its reaction irreversible. 
D) Some synthetases bind the anticodon and others do not.

Question 20

Which statement is true about the number of initiation and STOP codons?

Accepted Answer

A) One initiation codon;one STOP codon. 
B) One initiation codon;multiple STOP codons. 
C) Multiple initiation codons;one STOP codon. 
D) Multiple codons for both initiation and STOP. 
A) One initiation codon;one STOP codon. 
B) One initiation codon;multiple STOP codons. 
C) Multiple initiation codons;one STOP codon. 
D) Multiple codons for both initiation and STOP.

Exam 22: Protein Synthesis

Use the table below to determine which template strand DNA sequence (written in the 5' → 3' direction)specifies the tripeptide with the sequence gly-ala-leu.

For each amino acid added to a polypeptide chain,________ phosphoanhydride bonds are cleaved.

Class II aminoacyl-tRNA synthetases are often multimeric enzymes that do not bind to the anticodon.

There are five times more ribosomes in eukaryotic cells than in most bacterial cells.

The 5' end and the region near the 3' end of tRNA molecules are base-paired to each other forming

How are the termination codons different from other codons?

Inosinate (I)is an acetylated form of G and it can base-pair with A,C,or U.

Which is not true about the genetic code?

What provides most of the energy needed for protein synthesis?

Peptidyl transferase catalyzes peptide bond formation,and the activity is contained within the protein portion of the large ribosomal subunit.

Tryptophan synthesis can be controlled by a process called attenuation in which the levels of tryptophan in the cell control translation by

The processing of ribosomal RNA precursors includes binding of six or seven ribosomal proteins before assembly of the ribosome begins.

The main control of the rate of globin synthesis is due to the activity of GEF (guanine nucleotide exchange factor).

Which statement is false concerning ribosomes and their components?

Of all the possible triplet codons,________ do not code for an amino acid.

How many possible codons (of normal size)are possible using the bases found in DNA?

EF-Ts promotes the dissociation of GDP from the EF-Tu-GDP complex to recycle this elongation factor.

The reading frame of DNA is fixed by

Which statement is false concerning aminoacyl-tRNA synthetase?

Which statement is true about the number of initiation and STOP codons?

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Electron Transport and Atp Synthesis

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

DNA Replication, repair, and Recombination

Transcription and RNA Processing

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