Exam 16: Lipid Metabolism

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If the carbonyl carbon of a fatty acyl CoA molecule with a C10 chain is labeled with 14C,how many rounds of β-oxidation are required to produce a radioactively labeled acetyl CoA?

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Which enzyme is needed for the oxidation of odd-chain saturated fatty acids that is not needed for even-chain fatty acids?

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Fatty acid synthesis is different in bacteria than in eukaryotic cells because ________.

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Ketone bodies are synthsized in the ________ from ________.

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The intermediate 1,2-diacylglycerol can lead to the synthesis of all but which substance below?

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Each of the following is a principle hormonal regulator of fatty acid metabolism,except

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Which dietary lipid usually contains no ester bonds?

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Animals use a type I fatty acid synthesis system (FAS I)while bacteria use a type II fatty acid synthesis system (FAS II).

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The pathway describing the formation of ether lipids in mammals begins with

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CoA derivatives are the active thioesters in fatty acid oxidation.

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Fatty acids are oxidized in the ________.

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All of the following occur during synthesis of ether lipids except

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While mutation of genes for the biosynthesis of sphingolipids are probably lethal,mutations in genes for the degradation of sphingolipids often lead to metabolic diseases such as Tay-Sachs disease.

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The long chain fatty acid arachidonate is the precursor for many eicosanoids.

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Which of the following is true for carboxylation of acetyl CoA?

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Phosphatidate is an intermediate in the synthesis of ________.

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Eicosanoids,like hormones,are transferred through the blood stream to areas targeted for activities such as vasoconstriction,sensitivity,inflammation and swelling.

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Lysosomal storage diseases occur when mutations cause defects in ________.

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High levels of VLDLs have been found to have a protective effect against atherosclerosis.

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A patient is found to have a high concentration of cholesterol in the blood and deposits of cholesterol under the skin.The patient is diagnosed with familial hypercholesterolemia.What is the likely cause of this condition?

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