Question 1

What type of reaction is the conversion of fumarate to malate?

Accepted Answer

A) Oxidative decarboxylation. 
B) Hydration. 
C) Dehydrogenation. 
D) Condensation. 
A) Oxidative decarboxylation. 
B) Hydration. 
C) Dehydrogenation. 
D) Condensation.

Question 2

Citric acid cycle components are dissolved in the cytosol for all prokaryotic and eukaryotic species.

Accepted Answer

A) True 
 B)False

Question 3

The eukaryotic succinate dehydrogenase complex is dissolved in the mitochondrial matrix.

Accepted Answer

A) True 
 B)False

Question 4

Pyruvate translocase is a(n)________ protein that transports ________.

Accepted Answer

A) antiport;pyruvate and H+ in opposite directions 
B) uniport;only pyruvate 
C) symport;pyruvate and H+ in the same direction 
D) antiport;pyruvate and CO2 in opposite directions 
A) antiport;pyruvate and H+ in opposite directions 
B) uniport;only pyruvate 
C) symport;pyruvate and H+ in the same direction 
D) antiport;pyruvate and CO2 in opposite directions

Question 5

The following enzyme(s)is/are unique to the glyoxylate cycle:

Accepted Answer

A) Malate synthase. 
B) Malate dehydrogenase. 
C) Isocitrate lyase. 
D) All of the above. 
E) A and C only. 
A) Malate synthase. 
B) Malate dehydrogenase. 
C) Isocitrate lyase. 
D) All of the above. 
E) A and C only.

Question 6

Which enzyme catalyzes the conversion of citrate to isocitrate?

Accepted Answer

A) Aldolase. 
B) Citrate synthase. 
C) Citrate isomerase. 
D) Aconitase. 
A) Aldolase. 
B) Citrate synthase. 
C) Citrate isomerase. 
D) Aconitase.

Question 7

Isocitrate is more easily oxidized than citrate because it has a secondary alcohol group,whereas citrate's alcohol group is tertiary.

Accepted Answer

A) True 
 B)False

Question 8

Pyruvate dehydrogenase is inactivated by phosphorylation.This can be prevented by a chemical,dichloroacetate,and this disrupts many cancer cells because they are

Accepted Answer

A) aerobic. 
B) anaerobic. 
C) fast growing. 
D) non-fermenting. 
A) aerobic. 
B) anaerobic. 
C) fast growing. 
D) non-fermenting.

Question 9

Each of the following leads to a biosynthetic pathway except

Accepted Answer

A) a-ketoglutarate. 
B) succinyl CoA. 
C) oxaloacetate. 
D) citrate. 
E) None of the above. 
A) a-ketoglutarate. 
B) succinyl CoA. 
C) oxaloacetate. 
D) citrate. 
E) None of the above.

Question 10

Malonate

Accepted Answer

A) is a structural analog of succinate. 
B) binds to the substrate-binding site of the succinate dehydrogenase complex but does not react. 
C) undergoes an oxidation reaction. 
D) Both A and B. 
E) All of the above. 
A) is a structural analog of succinate. 
B) binds to the substrate-binding site of the succinate dehydrogenase complex but does not react. 
C) undergoes an oxidation reaction. 
D) Both A and B. 
E) All of the above.

Question 11

Which enzyme does not catalyze a reaction that releases carbon dioxide?

Accepted Answer

A) α-ketoglutarate dehydrogenase complex. 
B) Pyruvate dehydrogenase. 
C) Malate dehydrogenase. 
D) Isocitrate dehydrogenase. 
A) α-ketoglutarate dehydrogenase complex. 
B) Pyruvate dehydrogenase. 
C) Malate dehydrogenase. 
D) Isocitrate dehydrogenase.

Question 12

Which of the following are components of the succinate dehydrogenase complex?

Accepted Answer

A) FAD prosthetic group. 
B) Iron-sulfur clusters. 
C) Malonate. 
D) All of the above. 
E) A and B only. 
A) FAD prosthetic group. 
B) Iron-sulfur clusters. 
C) Malonate. 
D) All of the above. 
E) A and B only.

Question 13

Please match the following reactions to their respective energy yielding products.
Please note that a product may be used once,more than once,or not at all as an answer.
-Succinyl CoA synthetase

Accepted Answer

A) NADH 
B) QH² 
C) GTP or ATP 
A) NADH 
B) QH² 
C) GTP or ATP

Question 14

Which intermediate of the citric acid cycle has a plane of symmetry?

Accepted Answer

A) Succinate. 
B) Citrate. 
C) Succinyl CoA. 
D) α-ketoglutarate. 
A) Succinate. 
B) Citrate. 
C) Succinyl CoA. 
D) α-ketoglutarate.

Question 15

True statements about the glyoxylate cycle include

Accepted Answer

A) four carbon atoms of the acetyl group of acetyl CoA are released as carbon dioxide during operation of the glyoxylate cycle. 
B) the net formation of a four carbon molecule from two acetyl CoA molecules supplies a precursor that can be converted to glucose. 
C) the reaction catalyzed by malate synthase is the first bypass enzyme of the glyoxylate cycle. 
D) it is inactive in oily seed plants. 
A) four carbon atoms of the acetyl group of acetyl CoA are released as carbon dioxide during operation of the glyoxylate cycle. 
B) the net formation of a four carbon molecule from two acetyl CoA molecules supplies a precursor that can be converted to glucose. 
C) the reaction catalyzed by malate synthase is the first bypass enzyme of the glyoxylate cycle. 
D) it is inactive in oily seed plants.

Question 16

Metabolites moved across the mitochondrial membrane by transporters include

Accepted Answer

A) pyruvate. 
B) PEP. 
C) citrate and malate. 
D) All of the above. 
A) pyruvate. 
B) PEP. 
C) citrate and malate. 
D) All of the above.

Question 17

Which step in the citric acid cycle is a rearrangement reaction?

Accepted Answer

A) Succinyl CoA to succinate. 
B) Fumarate to L-malate. 
C) Citrate to isocitrate. 
D) Glucose 1,6-bisphosphate to fructose 1,6-bisphosphate. 
A) Succinyl CoA to succinate. 
B) Fumarate to L-malate. 
C) Citrate to isocitrate. 
D) Glucose 1,6-bisphosphate to fructose 1,6-bisphosphate.

Question 18

Which 5-carbon intermediate of the citric acid cycle is converted to a 4-carbon molecule with the release of carbon dioxide?

Accepted Answer

A) Fumarase. 
B) α-ketoglutarate. 
C) Succinate. 
D) Isocitrate. 
A) Fumarase. 
B) α-ketoglutarate. 
C) Succinate. 
D) Isocitrate.

Question 19

The glyoxylate cycle leads from two carbon compounds to glucose in each organism below except

Accepted Answer

A) animals. 
B) plants. 
C) bacteria. 
D) yeast. 
E) None of the above. 
A) animals. 
B) plants. 
C) bacteria. 
D) yeast. 
E) None of the above.

Question 20

The glyoxylate cycle is

Accepted Answer

A) a catabolic pathway in plants and some microorganisms. 
B) an anabolic pathway in plants and some microorganisms. 
C) regarded as a shunt within the citric acid cycle. 
D) A and C only. 
E) B and C only. 
A) a catabolic pathway in plants and some microorganisms. 
B) an anabolic pathway in plants and some microorganisms. 
C) regarded as a shunt within the citric acid cycle. 
D) A and C only. 
E) B and C only.

Exam 13: The Citric Acid Cycle

What type of reaction is the conversion of fumarate to malate?

Citric acid cycle components are dissolved in the cytosol for all prokaryotic and eukaryotic species.

The eukaryotic succinate dehydrogenase complex is dissolved in the mitochondrial matrix.

Pyruvate translocase is a(n)________ protein that transports ________.

The following enzyme(s)is/are unique to the glyoxylate cycle:

Which enzyme catalyzes the conversion of citrate to isocitrate?

Isocitrate is more easily oxidized than citrate because it has a secondary alcohol group,whereas citrate's alcohol group is tertiary.

Pyruvate dehydrogenase is inactivated by phosphorylation.This can be prevented by a chemical,dichloroacetate,and this disrupts many cancer cells because they are

Each of the following leads to a biosynthetic pathway except

Malonate

Which enzyme does not catalyze a reaction that releases carbon dioxide?

Which of the following are components of the succinate dehydrogenase complex?

Please match the following reactions to their respective energy yielding products. Please note that a product may be used once,more than once,or not at all as an answer. -Succinyl CoA synthetase

Which intermediate of the citric acid cycle has a plane of symmetry?

True statements about the glyoxylate cycle include

Metabolites moved across the mitochondrial membrane by transporters include

Which step in the citric acid cycle is a rearrangement reaction?

Which 5-carbon intermediate of the citric acid cycle is converted to a 4-carbon molecule with the release of carbon dioxide?

The glyoxylate cycle leads from two carbon compounds to glucose in each organism below except

The glyoxylate cycle is

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

Electron Transport and Atp Synthesis

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

DNA Replication, repair, and Recombination

Transcription and RNA Processing

Protein Synthesis

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Pyruvate translocase is a(n) protein that transports .