Question 1

The pattern of G-bands on each member of a homologous pair of chromosomes is usually different.

Accepted Answer

A) True 
 B)False

Question 2

Chromosome painting is a relatively new technique in karyotype analysis. Which one of the following statements about chromosome painting is false?

Accepted Answer

A)  It is done to make abnormalities easier to detect. 
B)  The dyes used to create color are fluorescent dyes. 
C)  The dyes are attached to DNA sequences. 
D)  In a normal karyotype, each chromosome appears with bands of different colors. 
E)  Each of the 24 different chromosome types has a unique appearance. 
A)  It is done to make abnormalities easier to detect. 
B)  The dyes used to create color are fluorescent dyes. 
C)  The dyes are attached to DNA sequences. 
D)  In a normal karyotype, each chromosome appears with bands of different colors. 
E)  Each of the 24 different chromosome types has a unique appearance.

Question 3

A chromosome whose centromere is close to the end of the chromosome is called _______.

Accepted Answer

A)  submetacentric 
B)  metacentric 
C)  acrocentric 
D)  mesocentric 
E)  pericentric 
A)  submetacentric 
B)  metacentric 
C)  acrocentric 
D)  mesocentric 
E)  pericentric

Question 4

The most common sex chromosome abnormality found in spontaneous abortions is 45, X.

Accepted Answer

A) True 
 B)False

Question 5

The placement of chromosomes into one of the seven groups in a karyotype is based on the chromosome's

Accepted Answer

A)  size. 
B)  centromere position. 
C)  banding pattern. 
D)  size and centromere position only. 
E)  all of these. 
A)  size. 
B)  centromere position. 
C)  banding pattern. 
D)  size and centromere position only. 
E)  all of these.

Question 6

What percentage of parents decide to terminate a Down Syndrome pregnancy?

Accepted Answer

A)  10 percent 
B)  30 percent 
C)  50 percent 
D)  70 percent 
E)  90 percent 
A)  10 percent 
B)  30 percent 
C)  50 percent 
D)  70 percent 
E)  90 percent

Question 7

What is the number of chromosomes in a human tetraploid cell? ____________________

Accepted Answer

The answer of What is the number of chromosomes in...

Question 8

The degree of mental retardation in a Down syndrome fetus is predictable.

Accepted Answer

A) True 
 B)False

Question 9

In this type of prenatal diagnosis, karyotype analysis can be performed as early as 8 weeks.

Accepted Answer

A)  Amniocentesis 
B)  Chorionic villus sampling 
C)  Cell-free fetal DNA analysis 
D)  Pre-genetic diagnosis 
E)  Polyploid analysis 
A)  Amniocentesis 
B)  Chorionic villus sampling 
C)  Cell-free fetal DNA analysis 
D)  Pre-genetic diagnosis 
E)  Polyploid analysis

Question 10

Figure 6.21 shows identical twins who differ in their sex chromosome constitution. How could this condition arise?

Accepted Answer

Figure 6.21, which is not visible in thi

Question 11

Two sets of parents who have children with Down syndrome meet at a clinic. The Williams know that their son has trisomy 21. The Millers have two affected children and Mrs. Miller has had two miscarriages. Why should the Millers be more concerned about future reproductive problems than the Williams? How did Down syndrome occur in each of these families?

Accepted Answer

The Millers should be more concerned abo

Question 12

A translocation involving chromosome 21 can result in

Accepted Answer

A)  a risk for Down syndrome independent of maternal age. 
B)  a risk for Down syndrome dependent on paternal age. 
C)  no increased risk outside of maternal age. 
D)  lowering the risk of Down syndrome. 
E)  no change in the risk for Down syndrome. 
A)  a risk for Down syndrome independent of maternal age. 
B)  a risk for Down syndrome dependent on paternal age. 
C)  no increased risk outside of maternal age. 
D)  lowering the risk of Down syndrome. 
E)  no change in the risk for Down syndrome.

Question 13

The two most common types of polyploidy in humans are

Accepted Answer

A)  trisomy and aneuploidy. 
B)  triploidy and haploidy. 
C)  triploidy and tetraploidy. 
D)  tetraploidy and diploidy. 
E)  haploidy and diploidy. 
A)  trisomy and aneuploidy. 
B)  triploidy and haploidy. 
C)  triploidy and tetraploidy. 
D)  tetraploidy and diploidy. 
E)  haploidy and diploidy.

Question 14

The banding patterns are different for non-homologous chromosomes.

Accepted Answer

A) True 
 B)False

Question 15

When making a karyotype, what is the effect of placing lymphocytes in a low-salt solution?

Accepted Answer

A)  It makes the chromosomes more visible. 
B)  It initiates cell division. 
C)  It stops the cells in metaphase. 
D)  It helps separate the chromosomes. 
E)  It causes the cells to swell. 
A)  It makes the chromosomes more visible. 
B)  It initiates cell division. 
C)  It stops the cells in metaphase. 
D)  It helps separate the chromosomes. 
E)  It causes the cells to swell.

Question 16

Comment on the following statement: "Since monosomy (2n-1) for autosomes is lethal, no individuals with 45 chromosomes, including a normal pair of sex chromosomes, exist."

Accepted Answer

This statement is not entirely accurate.

Question 17

Among abnormalities of the sex chromosomes, no cases of OY individuals are known, although XO individuals have been found. Why do you think this is the case? Is this evidence for differences in genetic content between the X and Y chromosome?

Accepted Answer

The lack of known cases of OY individual

Question 18

Describe the chromosomal constitution of the four cells of meiosis if a nondisjunction event occurred in Anaphase II.

Accepted Answer

If a nondisjunction event occurred in An

Question 19

In general, how do sex chromosome aneuploidies differ from autosomal aneuploidies?

Accepted Answer

Sex chromosome aneuploidies and autosoma

The pattern of G-bands on each member of a homologous pair of chromosomes is usually different.

Chromosome painting is a relatively new technique in karyotype analysis. Which one of the following statements about chromosome painting is false?

A chromosome whose centromere is close to the end of the chromosome is called _______.

The most common sex chromosome abnormality found in spontaneous abortions is 45, X.

The placement of chromosomes into one of the seven groups in a karyotype is based on the chromosome's

What percentage of parents decide to terminate a Down Syndrome pregnancy?

What is the number of chromosomes in a human tetraploid cell? ____________________

The degree of mental retardation in a Down syndrome fetus is predictable.

In this type of prenatal diagnosis, karyotype analysis can be performed as early as 8 weeks.

Figure 6.21 shows identical twins who differ in their sex chromosome constitution. How could this condition arise?

A translocation involving chromosome 21 can result in

The two most common types of polyploidy in humans are

The banding patterns are different for non-homologous chromosomes.

When making a karyotype, what is the effect of placing lymphocytes in a low-salt solution?

Comment on the following statement: "Since monosomy (2n-1) for autosomes is lethal, no individuals with 45 chromosomes, including a normal pair of sex chromosomes, exist."

Among abnormalities of the sex chromosomes, no cases of OY individuals are known, although XO individuals have been found. Why do you think this is the case? Is this evidence for differences in genetic content between the X and Y chromosome?

Describe the chromosomal constitution of the four cells of meiosis if a nondisjunction event occurred in Anaphase II.

In general, how do sex chromosome aneuploidies differ from autosomal aneuploidies?

A Perspective on Human Genetics

Cells and Cell Division

Transmission of Genes From Generation to Generation

Pedigree Analysis in Human Genetics

Complex Patterns of Inheritance

Development and Sex Determination

DNA Structure and Chromosomal Organization

Gene Expression: From Genes to Proteins

From Proteins to Phenotypes

Mutation: the Source of Genetic Variation

Genes and Cancer

An Introduction to Genetic Technology

Biotechnology and Society

Genomes and Genomics

Reproductive Technology, Genetic Testing, and Gene Therapy

Genes and the Immune System

Genetics of Behavior

Population Genetics and Human Evolution

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Exam 6: Cytogenetics: Karyotypes and Chromosome Aberrations

The pattern of G-bands on each member of a homologous pair of chromosomes is usually different.

Chromosome painting is a relatively new technique in karyotype analysis. Which one of the following statements about chromosome painting is false?

A chromosome whose centromere is close to the end of the chromosome is called _______.

The most common sex chromosome abnormality found in spontaneous abortions is 45, X.

The placement of chromosomes into one of the seven groups in a karyotype is based on the chromosome's

What percentage of parents decide to terminate a Down Syndrome pregnancy?

What is the number of chromosomes in a human tetraploid cell? ____________________

The degree of mental retardation in a Down syndrome fetus is predictable.

In this type of prenatal diagnosis, karyotype analysis can be performed as early as 8 weeks.

Figure 6.21 shows identical twins who differ in their sex chromosome constitution. How could this condition arise?

A translocation involving chromosome 21 can result in

The two most common types of polyploidy in humans are

The banding patterns are different for non-homologous chromosomes.

When making a karyotype, what is the effect of placing lymphocytes in a low-salt solution?

Comment on the following statement: "Since monosomy (2n-1) for autosomes is lethal, no individuals with 45 chromosomes, including a normal pair of sex chromosomes, exist."

Among abnormalities of the sex chromosomes, no cases of OY individuals are known, although XO individuals have been found. Why do you think this is the case? Is this evidence for differences in genetic content between the X and Y chromosome?

Describe the chromosomal constitution of the four cells of meiosis if a nondisjunction event occurred in Anaphase II.

In general, how do sex chromosome aneuploidies differ from autosomal aneuploidies?

A Perspective on Human Genetics

Cells and Cell Division

Transmission of Genes From Generation to Generation

Pedigree Analysis in Human Genetics

Complex Patterns of Inheritance

Development and Sex Determination

DNA Structure and Chromosomal Organization

Gene Expression: From Genes to Proteins

From Proteins to Phenotypes

Mutation: the Source of Genetic Variation

Genes and Cancer

An Introduction to Genetic Technology

Biotechnology and Society

Genomes and Genomics

Reproductive Technology, Genetic Testing, and Gene Therapy

Genes and the Immune System

Genetics of Behavior

Population Genetics and Human Evolution

Filters