Question 1

A characteristic of the glycerol phosphate shuttle is

Accepted Answer

A)  it shuttles NADH across the mitochondrial membrane to yield 5 ATP\NADH 
B)  it shuttles the electrons from NADH across the mitochondrial membrane to FADH2, yielding 5 ATP\NADH 
C)  it only operates efficiently at high levels of NADH 
D)  malate is a key component in the shuttle process 
A)  it shuttles NADH across the mitochondrial membrane to yield 5 ATP\NADH 
B)  it shuttles the electrons from NADH across the mitochondrial membrane to FADH2, yielding 5 ATP\NADH 
C)  it only operates efficiently at high levels of NADH 
D)  malate is a key component in the shuttle process

Question 2

Conformation changes in proteins are crucial in the synthesis of ATP in the mitochondria.

Accepted Answer

A) True 
 B)False

Question 3

An alternative mode of entry into the electron transport chain is the oxidation of

Accepted Answer

A)  malate to oxalosuccinate. 
B)  succinate to fumarate. 
C)  isocitrate to α -ketoglutarate. 
D)  α -ketoglutarate to succinyl-CoA. 
A)  malate to oxalosuccinate. 
B)  succinate to fumarate. 
C)  isocitrate to α -ketoglutarate. 
D)  α -ketoglutarate to succinyl-CoA.

Question 4

In the conformational coupling mechanism for oxidative phosphorylation, the effect of the proton gradient is

Accepted Answer

A)  to inhibit conformational changes in the ATP synthase 
B)  to create more sites for ATP synthesis 
C)  the release of tightly bound ATP from the synthase 
D)  all of these 
E)  none of these 
A)  to inhibit conformational changes in the ATP synthase 
B)  to create more sites for ATP synthesis 
C)  the release of tightly bound ATP from the synthase 
D)  all of these 
E)  none of these

Question 5

Mitochondrial membranes can be fragmented into small vesicles which still synthesize ATP; intact mitochondria are not required.

Accepted Answer

A) True 
 B)False

Question 6

If a cyclist started a race and rode at a near maximum speed, which of the following fuel sources would be used up first?

Accepted Answer

A)  fat in the muscle cells 
B)  muscle glycogen 
C)  liver glycogen 
D)  muscle creatine-phosphate 
E)  all of these would be exhausted simultaneously 
A)  fat in the muscle cells 
B)  muscle glycogen 
C)  liver glycogen 
D)  muscle creatine-phosphate 
E)  all of these would be exhausted simultaneously

Question 7

Most of the reactions of electron transport in the mitochondria occur

Accepted Answer

A)  on the outer membrane 
B)  on the inner membrane. 
C)  in the mitochondrial matrix. 
D)  in the intermembrane space. 
E)  in the cytosol. 
A)  on the outer membrane 
B)  on the inner membrane. 
C)  in the mitochondrial matrix. 
D)  in the intermembrane space. 
E)  in the cytosol.

Question 8

Electron flow in the mitochondria follows this pathway:

Accepted Answer

A)  NADH → FMN → Coenzyme Q → Cyt A → Cyt B → Cyt C → O2 
B)  NADH → FMN → Cyt B → Coenzyme Q → Cyt C → Cyt A → O2 
C)  FMNH2 → NAD → Coenzyme Q → Cyt B → Cyt C → Cyt A → O2 
D)  NADH → FMN → Coenzyme Q → Cyt B → Cyt C → Cyt A → O2 
E)  NADH → FMN → Cyt B → Cyt C → Coenzyme Q → Cyt A → O2 
A)  NADH → FMN → Coenzyme Q → Cyt A → Cyt B → Cyt C → O2 
B)  NADH → FMN → Cyt B → Coenzyme Q → Cyt C → Cyt A → O2 
C)  FMNH2 → NAD → Coenzyme Q → Cyt B → Cyt C → Cyt A → O2 
D)  NADH → FMN → Coenzyme Q → Cyt B → Cyt C → Cyt A → O2 
E)  NADH → FMN → Cyt B → Cyt C → Coenzyme Q → Cyt A → O2

Question 9

Which of the following was not evidence that supported Mitchell's chemiosmotic coupling hypothesis?

Accepted Answer

A)  Closed vessicles were required. Phosphorylation did not occur in a completely soluble environment. 
B)  Vessicles could be prepared from mitochondria and the assymetric location of electron transport protein could be shown. 
C)  The existence of the pH gradient could be demonstrated 
D)  The transfer of electrons from complex I to oxygen was shown 
E)  none of these 
A)  Closed vessicles were required. Phosphorylation did not occur in a completely soluble environment. 
B)  Vessicles could be prepared from mitochondria and the assymetric location of electron transport protein could be shown. 
C)  The existence of the pH gradient could be demonstrated 
D)  The transfer of electrons from complex I to oxygen was shown 
E)  none of these

Question 10

Another name for Complex II in the electron transport chain is

Accepted Answer

A)  cytochrome c oxidase. 
B)  NADH-CoQ oxidoreductase. 
C)  cytochrome bc1 complex. 
D)  succinate-CoQ oxidoreductase. 
A)  cytochrome c oxidase. 
B)  NADH-CoQ oxidoreductase. 
C)  cytochrome bc1 complex. 
D)  succinate-CoQ oxidoreductase.

Question 11

The Q cycle refers to flow of electrons from

Accepted Answer

A)  NADH to coenzyme Q via Complex I. 
B)  FADH2 to coenzyme Q via Complex II. 
C)  coenzyme Q to cytochrome c via Complex III. 
D)  coenzyme Q to NADH. 
E)  none of these 
A)  NADH to coenzyme Q via Complex I. 
B)  FADH2 to coenzyme Q via Complex II. 
C)  coenzyme Q to cytochrome c via Complex III. 
D)  coenzyme Q to NADH. 
E)  none of these

Question 12

Which of the following is true?

Accepted Answer

A)  Uncoupling agents can work by disrupting the flow of protons during ATP synthesis. 
B)  Uncoupling agents prevent the flow of electrons during electron transport 
C)  Uncoupling agents always block the flow of protons through the ATPase 
D)  none of these is true 
A)  Uncoupling agents can work by disrupting the flow of protons during ATP synthesis. 
B)  Uncoupling agents prevent the flow of electrons during electron transport 
C)  Uncoupling agents always block the flow of protons through the ATPase 
D)  none of these is true

Question 13

Reduction potentials (E ° ) are measured by reading a voltmeter, which measures the electron flow between two reaction chambers.

Accepted Answer

A) True 
 B)False

Question 14

Complex III of the electron transport chain oxidizes ____, reduces ____, and ____ protons in the process.

Accepted Answer

A)  coenzyme Q; cytochrome c ; pumps 
B)  coenzyme Q; cytochrome c ; doesn't pump 
C)  cytochrome c ; coenzyme Q; pumps 
D)  cytochrome c ; coenzyme Q; doesn't pump 
A)  coenzyme Q; cytochrome c ; pumps 
B)  coenzyme Q; cytochrome c ; doesn't pump 
C)  cytochrome c ; coenzyme Q; pumps 
D)  cytochrome c ; coenzyme Q; doesn't pump

Question 15

Creatine supplements work best for long distance exercise, rather than for quick spurts of energy.

Accepted Answer

A) True 
 B)False

Question 16

The factor that couples electron transport to phosphorylation of ADP is

Accepted Answer

A)  a protein oligomer 
B)  a protein monomer 
C)  gramicidin A 
D)  valinomycin 
A)  a protein oligomer 
B)  a protein monomer 
C)  gramicidin A 
D)  valinomycin

Question 17

What is the net yield of ATP per glucose molecule that passes through all of aerobic respiration (glucose → CO2 + H2O)?

Accepted Answer

A)  2 
B)  4 
C)  6 
D)  30 − 32, dependent on the shuttle system used. 
A)  2 
B)  4 
C)  6 
D)  30 − 32, dependent on the shuttle system used.

Question 18

Which of the following procedures is most unique to the determination of the order of the passage of electrons through the electron transport chain was determined

Accepted Answer

A)  use of respiratory inhibitors 
B)  spectroscopy 
C)  isolation of intact mitochondria 
D)  none of these have anything to do with determining the order 
A)  use of respiratory inhibitors 
B)  spectroscopy 
C)  isolation of intact mitochondria 
D)  none of these have anything to do with determining the order

Question 19

Which complex of the electron transport chain does NOT contain an iron-sulfur cluster?

Accepted Answer

A)  Complex I 
B)  Complex II 
C)  Complex III 
D)  Complex IV 
A)  Complex I 
B)  Complex II 
C)  Complex III 
D)  Complex IV

Question 20

​ Which part of mitochondria develops a proton gradient as a result of electron transport?

Accepted Answer

A)  Outer mitochondrial membrane 
B)  Inner mitochondrial membrane 
C)  Cristae 
D)  Matrix 
A)  Outer mitochondrial membrane 
B)  Inner mitochondrial membrane 
C)  Cristae 
D)  Matrix

Exam 20: Electron Transport and Oxidative Phosphorylation

A characteristic of the glycerol phosphate shuttle is

Conformation changes in proteins are crucial in the synthesis of ATP in the mitochondria.

An alternative mode of entry into the electron transport chain is the oxidation of

In the conformational coupling mechanism for oxidative phosphorylation, the effect of the proton gradient is

Mitochondrial membranes can be fragmented into small vesicles which still synthesize ATP; intact mitochondria are not required.

If a cyclist started a race and rode at a near maximum speed, which of the following fuel sources would be used up first?

Most of the reactions of electron transport in the mitochondria occur

Electron flow in the mitochondria follows this pathway:

Which of the following was not evidence that supported Mitchell's chemiosmotic coupling hypothesis?

Another name for Complex II in the electron transport chain is

The Q cycle refers to flow of electrons from

Which of the following is true?

Reduction potentials (E ° ) are measured by reading a voltmeter, which measures the electron flow between two reaction chambers.

Complex III of the electron transport chain oxidizes ____, reduces ____, and ____ protons in the process.

Creatine supplements work best for long distance exercise, rather than for quick spurts of energy.

The factor that couples electron transport to phosphorylation of ADP is

What is the net yield of ATP per glucose molecule that passes through all of aerobic respiration (glucose → CO2 + H2O)?

Which of the following procedures is most unique to the determination of the order of the passage of electrons through the electron transport chain was determined

Which complex of the electron transport chain does NOT contain an iron-sulfur cluster?

​ Which part of mitochondria develops a proton gradient as a result of electron transport?

Biochemistry and the Organization of Cells

Water the Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins Enzymes

The Behavior of Proteins Enzymes Mechanisms and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids How Structure Conveys Information

Biosynthesis of Nucleic Acids Replication

Transcription of the Genetic Code the Biosynthesis of Rna

Protein Synthesis Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses Cancer and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism Cellular Signaling

Filters

Complex III of the electron transport chain oxidizes , reduces , and protons in the process.

What is the net yield of ATP per glucose molecule that passes through all of aerobic respiration (glucose → CO₂ + H₂O)?

Which part of mitochondria develops a proton gradient as a result of electron transport?