Question 1

What is comparative genomics?

Accepted Answer

Comparative genomics is a relatively new

Question 2

Which two factors contribute significantly to the wide ranges of genome size among eukaryotes?

Accepted Answer

The presence of introns and re

Question 3

Present a general definition for a multigene family and how it relates to a superfamily.

Accepted Answer

Multigene families share DNA sequence ho

Question 4

What is meant by the term pseudogene?

Accepted Answer

Pseudogenes are nonfunctional versions o

Question 5

Explain the goal of the emerging discipline called systems biology.

Accepted Answer

Systems biology seeks to incor

Question 6

Numerous scientists around the world have proposed to sequence 10,000 vertebrate genomes in five years. What is the name of this plan?

Accepted Answer

A)  Vertebrate Beginnings 
B)  Vertebrate Enlightenment 
C)  Bigger Than Life Plan 
D)  Genome 10K 
E)  10K or Bust 
A)  Vertebrate Beginnings 
B)  Vertebrate Enlightenment 
C)  Bigger Than Life Plan 
D)  Genome 10K 
E)  10K or Bust

Question 7

It appears as if about 5000 functional genes is the minimum genome size necessary for life of a prokaryote.

Accepted Answer

A) True 
 B)False

Question 8

Multigene families are characterized by clusters of tandemly arranged unique pseudogenes organized as operons.

Accepted Answer

A) True 
 B)False

Question 9

One major difference between prokaryotic and eukaryotic genes is that eukaryotic
genes can contain internal sequences, called message.

Accepted Answer

intervening sequence

Question 10

What is meant by the term low gene density? Give an example of an organism with low gene density.

Accepted Answer

Low gene density is common in

Question 11

Proteomics is the _.

Accepted Answer

A)  changing of the terminal sequences of proteins to alter their function 
B)  harvesting of proteins from a cell to determine their economic value 
C)  manipulation of amino acid sequences in proteins to alter their function 
D)  rational design of drugs based on protein structure 
E)  process of defining the complete set of proteins encoded by a genome 
A)  changing of the terminal sequences of proteins to alter their function 
B)  harvesting of proteins from a cell to determine their economic value 
C)  manipulation of amino acid sequences in proteins to alter their function 
D)  rational design of drugs based on protein structure 
E)  process of defining the complete set of proteins encoded by a genome

Question 12

A bacterial operon _.

Accepted Answer

A)  contains information for more than one protein product 
B)  is capped at the 5' end and carries a poly -A tail at the 3' end 
C)  is void of start (AUG) and termination (UAA, UGA, UAG) triplets 
D)  contains information for one protein product 
E)  None of the answers listed is correct. 
A)  contains information for more than one protein product 
B)  is capped at the 5' end and carries a poly -A tail at the 3' end 
C)  is void of start (AUG) and termination (UAA, UGA, UAG) triplets 
D)  contains information for one protein product 
E)  None of the answers listed is correct.

Question 13

Typically, bacterial DNA contains less repetitive DNA than eukaryotic DNA.

Accepted Answer

A) True 
 B)False

Question 14

Most of the eukaryotic genomes described in the text have more than

Accepted Answer

A)  50 chromosomes 
B)  100,000 genes 
C)  ten million genes 
D)  a million base pairs 
E)  50,000 genes 
A)  50 chromosomes 
B)  100,000 genes 
C)  ten million genes 
D)  a million base pairs 
E)  50,000 genes

Question 15

Mycoplasma are among the smallest and perhaps the simplest self -replicating prokaryotes known. M. genitalium contains a genome of 0.58 Mb. Approximately how many genes does this bacterium contain?

Accepted Answer

A)  between 400 and 550 
B)  1200 
C)  3000 
D)  426,000 
E)  12 
A)  between 400 and 550 
B)  1200 
C)  3000 
D)  426,000 
E)  12

Question 16

Briefly describe general trends relating to DNA content and gene number in major groups of organisms.

Accepted Answer

Eukaryotes contain more DNA in their gen

Question 17

In what way will the discipline called metagenomics contribute to human health and welfare?

Accepted Answer

Metagenomics, also called environmental

Question 18

The dog (Canis familiaris) genome has recently been sequenced. About how many of the dog's genes are shared with humans?

Accepted Answer

The answer of The dog (Canis familiaris) genome has recently...

Question 19

Describe the organization of the a -globin gene in humans.

Accepted Answer

The a -group spans more than 30 kb and c

Question 20

Introns are found only in prokaryotic genomes.

Accepted Answer

A) True 
 B)False

Exam 18: Genomics and Proteomics

What is comparative genomics?

Which two factors contribute significantly to the wide ranges of genome size among eukaryotes?

Present a general definition for a multigene family and how it relates to a superfamily.

What is meant by the term pseudogene?

Explain the goal of the emerging discipline called systems biology.

Numerous scientists around the world have proposed to sequence 10,000 vertebrate genomes in five years. What is the name of this plan?

It appears as if about 5000 functional genes is the minimum genome size necessary for life of a prokaryote.

Multigene families are characterized by clusters of tandemly arranged unique pseudogenes organized as operons.

One major difference between prokaryotic and eukaryotic genes is that eukaryotic genes can contain internal sequences, called message.

What is meant by the term low gene density? Give an example of an organism with low gene density.

Proteomics is the _.

A bacterial operon _.

Typically, bacterial DNA contains less repetitive DNA than eukaryotic DNA.

Most of the eukaryotic genomes described in the text have more than

Mycoplasma are among the smallest and perhaps the simplest self -replicating prokaryotes known. M. genitalium contains a genome of 0.58 Mb. Approximately how many genes does this bacterium contain?

Briefly describe general trends relating to DNA content and gene number in major groups of organisms.

In what way will the discipline called metagenomics contribute to human health and welfare?

The dog (Canis familiaris) genome has recently been sequenced. About how many of the dog's genes are shared with humans?

Describe the organization of the a -globin gene in humans.

Introns are found only in prokaryotic genomes.

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Modifications of Mendelian Ratios

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Linkage and Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bactierophages

DNA Structure and Analysis

DNA Replication and Recombination

Chromosome Structure and Dna Sequence Organization

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation, Dna Repair, and Transposition

Regulation of Gene Expression

The Genetics of Cancer

Recombinant Dna Technology

Applications and Ethics of Genetic Engineering and Biotechnology

Developmental Genetics

Quantitative Genetics and Multifactorial Traits

Population and Evolutionary Genetics

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