Exam 18: Genomics

A pharmaceutical company is developing a new drug to treat a rare disease.They need to determine which of the cell's proteins can bind the drug.What tool can help them survey the proteome for drug interactions?

Microarrays are created by robotically placing DNA on to a microscope slide and probing with

Identical copies of genes that can be transcribed simultaneously are called

Conserved arrangements of segments of DNA in related genomes are referred to as

To avoid confusion and facilitate ease of data interpretation, researchers working on cloned DNA from the same species use

A large portion (45%) of the human genome is composed of

You have been asked to construct a physical map of the baboon genome.What would be helpful in this task?

As a scientist working for an anti-bioterrorism task force, you are asked to evaluate some biological samples for the presence of Yersinia pestis, the organism that causes the plague.After confirming that the samples do contain Y.pestis, you instruct your team to begin sequencing the strain.Since the genome sequence of Y.pestis is already known, why would sequencing this strain be useful?

The sequencing method that cuts DNA segments into fragments, arranges those fragments based on overlapping nucleotide sequences, and then clones these fragments is called

The ends of chromosomes are called ________.

Mobile bits of DNA that can jump from one location on a chromosome to another location are called

You are studying a novel protein.To learn more about it, you performed a screen in yeast to identify proteins that could interact with it.From the screen you got a clone for a second gene.You had the clone sequenced, and you translated the gene sequence on your computer.What is the next logical step to learn more about the function of these two proteins?

Groups of related, but distinctly different genes that appear to have arisen from a single ancestral gene are referred to as

A human gene is composed of numerous fragments of protein-encoding information known as _______.

A transgene is best described as

A defining characteristic of draft sequences is that they have

Rice and its grain relatives, maize, barley, and wheat, diverged from a common ancestor 50 million years ago.However, the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called