Exam 16: Control of Gene Expression

You work for a pharmaceutical company that designs small RNAs, used to control expression of disease genes .The primary focus area of your research should be

Although the specific mechanism of RNA interference has not been fully defined, it involves

The main form of glucose repression in the lac operon is

The basic tool of genetic regulation is the ability of certain proteins to bind to specific

If you were given a bacterial strain with a mutation in the promoter region of the trp operon the most likely effect would be

The DNA-binding proteins of almost all regulatory proteins use one of a small set of shapes that enable them to fit into the DNA major groove.These shapes are called

Production of the iron-storing protein ferritin is regulated by aconitase, which binds to a 30-nucleotide sequence at the beginning of the ferritin mRNA and interferes with ribosome binding.Aconitase must be a

The lactose analog isopropyl-beta-D-thio-galactoside (IPTG) is often used to regulate gene expression systems in bacteria.IPTG does not act as a substrate for beta-galactosidase, but can bind to, and inactivate, the repressor.In this case, IPTG serves as a(n)

The primary transcripts in eukaryotes are most accurately described as

DNA methylation is the only known natural modification of DNA.It affects

The hallmark of multicellular organisms is their ability to

As a microbiologist you have been asked to investigate the regulation of a novel gene in a bacterial species.Given what is known about bacteria, the logical place to begin your investigation is

A defining characteristic of eukaryotic organisms is that they

If you were able to look very closely at a portion of DNA and find methylated histones, you would

In some organisms, the primary function of a gene in a cell is to participate in regulating the body as a whole rather than responding to the cell's immediate environment.These organisms would be

Elucidation of the histone code might

You have been asked to design a synthetic DNA motif, able to bind transcriptional regulatory proteins.The location on this motif that you will design for protein binding is the

Within its core a nucleosome contains ____ histones.

Small RNAs can regulate gene expression.One type, called micro RNA (miRNA), acts by binding directly to

In order for transcription to be initiated