Question 1

Acetylated histone tail lysines are associated with chromatin that is

Accepted Answer

A) open. 
B) closed. 
C) transcriptionally inactive. 
D) newly replicated. 
E) about to replicate. 
A) open. 
B) closed. 
C) transcriptionally inactive. 
D) newly replicated. 
E) about to replicate.

Question 2

What is the best definition for the FISH technique?

Accepted Answer

A) A method to fluorescently label different genes on metaphase chromosomes. 
B) A method to fluorescently label methylated histones associated with chromosomes. 
C) A method to fluorescently label heterochromatin. 
D) A method to fluorescently label euchromatin. 
A) A method to fluorescently label different genes on metaphase chromosomes. 
B) A method to fluorescently label methylated histones associated with chromosomes. 
C) A method to fluorescently label heterochromatin. 
D) A method to fluorescently label euchromatin.

Question 3

In what stage of mitosis are the highly-compacted chromosomes used for FISH?

Accepted Answer

A) prophase 
B) metaphase 
C) anaphase 
D) telophase 
E) never achieves this level of compaction 
A) prophase 
B) metaphase 
C) anaphase 
D) telophase 
E) never achieves this level of compaction

Question 4

When a cell loses telomerase activity, what is the predicted effect?

Accepted Answer

A) Telomeres will increase slightly with each cell division. 
B) After 30-50 divisions, the cell will show signs of senescence and then die. 
C) An immune stem cell will increase white blood cell production. 
D) A normal somatic cell will gain the ability to divide indefinitely. 
E) The cell will die immediately. 
A) Telomeres will increase slightly with each cell division. 
B) After 30-50 divisions, the cell will show signs of senescence and then die. 
C) An immune stem cell will increase white blood cell production. 
D) A normal somatic cell will gain the ability to divide indefinitely. 
E) The cell will die immediately.

Question 5

The creation of yeast artificial chromosomes preceded the production of the first yeast

Accepted Answer

A) synthetic chromosome that includes sequences from the human genome. 
B) synthetic chromosome that lacks about 50,000 bp from the normal yeast third chromosome. 
C) essential chromosome that combines the 1000 essential yeast genes into one chromosome. 
D) circular chromosome that does not require telomere sequences. 
A) synthetic chromosome that includes sequences from the human genome. 
B) synthetic chromosome that lacks about 50,000 bp from the normal yeast third chromosome. 
C) essential chromosome that combines the 1000 essential yeast genes into one chromosome. 
D) circular chromosome that does not require telomere sequences.

Question 6

Position-effect variegation of red and white eye color in Drosophila produces

Accepted Answer

A) one red eye and one white eyes. 
B) two red or two white eyes depending on which gene is dominant. 
C) eyes alternating red and white eye facets. 
D) eyes with red and white patches of varying sizes and positions. 
A) one red eye and one white eyes. 
B) two red or two white eyes depending on which gene is dominant. 
C) eyes alternating red and white eye facets. 
D) eyes with red and white patches of varying sizes and positions.

Question 7

Which pieces of evidence support the radial loop-scaffold model of DNA packaging?

Accepted Answer

A) Histone-depleted metaphase chromosomes still maintain their X-like shapes. 
B) Radial loop-scaffold DNA has been isolated and crystallized. 
C) Topoisomerase II assists in 100 Å packaging. 
D) Each G band formed by Giemsa staining represents a chromatin loop. 
A) Histone-depleted metaphase chromosomes still maintain their X-like shapes. 
B) Radial loop-scaffold DNA has been isolated and crystallized. 
C) Topoisomerase II assists in 100 Å packaging. 
D) Each G band formed by Giemsa staining represents a chromatin loop.

Question 8

The position of a gene located within a light G band on the short arm of chromosome 5 could be designated as

Accepted Answer

A) 5p13-pter. 
B) 5p13-qter. 
C) p513. 
D) 5q13-qter. 
E) q513. 
A) 5p13-pter. 
B) 5p13-qter. 
C) p513. 
D) 5q13-qter. 
E) q513.

Question 9

Histones and DNA have a strong attraction for each other because

Accepted Answer

A) DNA is positively charged and histones are negatively charged. 
B) both DNA and proteins are hydrophobic. 
C) DNA is negatively charged and histones are positively charged. 
D) like substances share common charges. 
A) DNA is positively charged and histones are negatively charged. 
B) both DNA and proteins are hydrophobic. 
C) DNA is negatively charged and histones are positively charged. 
D) like substances share common charges.

Question 10

In DNA, the 300 Å fiber is formed into structural loops.Responsibility for this function appears to lie with

Accepted Answer

A) histone H4. 
B) nucleosomase. 
C) histone H1. 
D) certain nonhistone proteins. 
E) remodeling complexes. 
A) histone H4. 
B) nucleosomase. 
C) histone H1. 
D) certain nonhistone proteins. 
E) remodeling complexes.

Question 11

The histone that appears to be responsible for organizing the 100 Å fibers into 300 Å fibers is

Accepted Answer

A) H4. 
B) H3. 
C) H2. 
D) H1. 
A) H4. 
B) H3. 
C) H2. 
D) H1.

Acetylated histone tail lysines are associated with chromatin that is

What is the best definition for the FISH technique?

In what stage of mitosis are the highly-compacted chromosomes used for FISH?

When a cell loses telomerase activity, what is the predicted effect?

The creation of yeast artificial chromosomes preceded the production of the first yeast

Position-effect variegation of red and white eye color in Drosophila produces

Which pieces of evidence support the radial loop-scaffold model of DNA packaging?

The position of a gene located within a light G band on the short arm of chromosome 5 could be designated as

Histones and DNA have a strong attraction for each other because

In DNA, the 300 Å fiber is formed into structural loops.Responsibility for this function appears to lie with

The histone that appears to be responsible for organizing the 100 Å fibers into 300 Å fibers is

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters

Exam 12: The Eukaryotic Chromosome

Acetylated histone tail lysines are associated with chromatin that is

What is the best definition for the FISH technique?

In what stage of mitosis are the highly-compacted chromosomes used for FISH?

When a cell loses telomerase activity, what is the predicted effect?

The creation of yeast artificial chromosomes preceded the production of the first yeast

Position-effect variegation of red and white eye color in Drosophila produces

Which pieces of evidence support the radial loop-scaffold model of DNA packaging?

The position of a gene located within a light G band on the short arm of chromosome 5 could be designated as

Histones and DNA have a strong attraction for each other because

In DNA, the 300 Å fiber is formed into structural loops.Responsibility for this function appears to lie with

The histone that appears to be responsible for organizing the 100 Å fibers into 300 Å fibers is

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters