Question 1

Cells grow primarily during which of the following cell-cycle phases?

Accepted Answer

A) G0 
B) G1 
C) G2 
D) M 
E) S 
A) G0 
B) G1 
C) G2 
D) M 
E) S

Question 2

Each of the following occurs during apoptosis of a cell except

Accepted Answer

A) flipping phosphatidylserine to the outer leaflet of the plasma membrane. 
B) DNase fragmentation of DNA. 
C) bleb formation. 
D) rupture of the cell,releasing cytoplasmic contents. 
E) formation of apoptotic bodies. 
A) flipping phosphatidylserine to the outer leaflet of the plasma membrane. 
B) DNase fragmentation of DNA. 
C) bleb formation. 
D) rupture of the cell,releasing cytoplasmic contents. 
E) formation of apoptotic bodies.

Question 3

Each of the following is true about cytochrome c in apoptosis except

Accepted Answer

A) It is released from mitochondria. 
B) It stimulates Ca2+ release from mitochondria. 
C) It stimulates Ca2+ release from the endoplasmic reticulum. 
D) It activates Rheb. 
E) It associates with Apaf1 to form an apoptosome. 
A) It is released from mitochondria. 
B) It stimulates Ca2+ release from mitochondria. 
C) It stimulates Ca2+ release from the endoplasmic reticulum. 
D) It activates Rheb. 
E) It associates with Apaf1 to form an apoptosome.

Question 4

A mutant cell in which sister chromatids get torn apart rather than separating correctly at anaphase most likely is deficient in

Accepted Answer

A) mitotic Cdk. 
B) mitotic cyclin. 
C) APC. 
D) topoisomerase II. 
E) helicase loaders. 
A) mitotic Cdk. 
B) mitotic cyclin. 
C) APC. 
D) topoisomerase II. 
E) helicase loaders.

Question 5

In an adult human stem cell that has a total of 48 chromosomes,how many chromatids are present at prophase of mitosis?

Accepted Answer

A) 12 
B) 24 
C) 48 
D) 72 
E) 96 
A) 12 
B) 24 
C) 48 
D) 72 
E) 96

Question 6

Each of the following provides evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole except

Accepted Answer

A) Stabilization of microtubules with the drug paclitaxel stops chromosome movement to a pole. 
B) Treatment that accelerates microtubule depolymerization causes chromosomes to move toward the poles more quickly. 
C) Antibody inhibition of kinesin depolymerization of kinetochore microtubules interferes with chromosome movement to a pole. 
D) Laser bleaching of labeled kinetochore microtubules indicates they shorten at the kinetochore as the chromosome moves toward a pole. 
E) All of the above are evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole. 
A) Stabilization of microtubules with the drug paclitaxel stops chromosome movement to a pole. 
B) Treatment that accelerates microtubule depolymerization causes chromosomes to move toward the poles more quickly. 
C) Antibody inhibition of kinesin depolymerization of kinetochore microtubules interferes with chromosome movement to a pole. 
D) Laser bleaching of labeled kinetochore microtubules indicates they shorten at the kinetochore as the chromosome moves toward a pole. 
E) All of the above are evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole.

Question 7

The cell-cycle phase that varies most in duration in various eukaryotic adult cell types is

Accepted Answer

A) M. 
B) G1. 
C) S) 
D) G2. 
E) G0. 
A) M. 
B) G1. 
C) S) 
D) G2. 
E) G0.

Question 8

Rapidly dividing embryonic cells shorten S-phase duration by increasing the number of ________.

Accepted Answer

The answer of Rapidly dividing embryonic cells shorten S-phase duration...

Question 9

Cell cycle studies have been facilitated by ________,a technique that allows rapid analysis and sorting of thousands or millions of cells.

Accepted Answer

The answer of Cell cycle studies have been facilitated by...

Question 10

A eukaryotic cell G2-M checkpoint assesses the status of

Accepted Answer

A) DNA replication. 
B) chromosome attachment to kinetochore microtubules. 
C) nutrient abundance. 
D) mitotic cyclin degradation. 
E) the presence of growth factors. 
A) DNA replication. 
B) chromosome attachment to kinetochore microtubules. 
C) nutrient abundance. 
D) mitotic cyclin degradation. 
E) the presence of growth factors.

Question 11

Epidermal growth factor is a mitogen,because it stimulates cells to divide.(1)Explain the role of Ras in epidermal growth factor signaling that results in cell division.(2)Design two experiments to prove that Ras is a key player in the EGF-activated pathway.(3)What assay other than cell division could you use to assess whether the EGF-Ras-MAPK pathway has been activated?

Accepted Answer

(1)Ras plays a key role in regulating th

Question 12

Each of the following statements regarding CD95-stimulated programmed cell death is true except

Accepted Answer

A) CD95 ligand binding with CD95 receptor stimulates recruitment of adaptor proteins. 
B) adaptor proteins stimulate the PI3K-Akt pathway. 
C) recruitment to sites of receptor clustering activates initiator caspase (caspase 8)activity. 
D) initiator caspases proteolytically cleave executioner procaspases (procaspase 3). 
E) a caspase cascade results in the cleavage of many types of proteins in the target cell. 
A) CD95 ligand binding with CD95 receptor stimulates recruitment of adaptor proteins. 
B) adaptor proteins stimulate the PI3K-Akt pathway. 
C) recruitment to sites of receptor clustering activates initiator caspase (caspase 8)activity. 
D) initiator caspases proteolytically cleave executioner procaspases (procaspase 3). 
E) a caspase cascade results in the cleavage of many types of proteins in the target cell.

Question 13

All of the following participate in apoptosis except

Accepted Answer

A) caspases. 
B) death signals. 
C) mitochondria. 
D) Bcl-2. 
E) APC ubiquitin ligase activity. 
A) caspases. 
B) death signals. 
C) mitochondria. 
D) Bcl-2. 
E) APC ubiquitin ligase activity.

Question 14

Which of the following families of proteins plays a central role in regulating the assembly and activation of the contractile ring?

Accepted Answer

A) Rho 
B) Cdk 
C) Polo 
D) Aurora 
E) Cdk activating kinase 
A) Rho 
B) Cdk 
C) Polo 
D) Aurora 
E) Cdk activating kinase

Question 15

Each of the following would inhibit cell progression through the cell cycle except

Accepted Answer

A) DNA damage during replication. 
B) kinase phosphorylation of mitotic Cdk. 
C) APC activity during M phase. 
D) unphosphorylated Retinoblastoma activity during G1. 
E) TGFβ signaling. 
A) DNA damage during replication. 
B) kinase phosphorylation of mitotic Cdk. 
C) APC activity during M phase. 
D) unphosphorylated Retinoblastoma activity during G1. 
E) TGFβ signaling.

Question 16

Starting with a diploid cell (2n = 4),illustrate the phases of mitosis with emphasis on the movement of chromosomes.

Accepted Answer

The answer of Starting with a diploid cell (2n =...

Question 17

A centromere contains repeated DNA sequences known as ________.

Accepted Answer

The answer of A centromere contains repeated DNA sequences known...

Question 18

The mechanism by which DNA is licensed to replicate only once during each S phase involves

Accepted Answer

A) CENP-A binding to CEN DNA. 
B) MCM proteins binding only to CEN DNA. 
C) MCM proteins binding only to replicated DNA. 
D) MCM proteins binding only to nonreplicated DNA. 
E) MCM proteins binding to both replicated and nonreplicated DNA. 
A) CENP-A binding to CEN DNA. 
B) MCM proteins binding only to CEN DNA. 
C) MCM proteins binding only to replicated DNA. 
D) MCM proteins binding only to nonreplicated DNA. 
E) MCM proteins binding to both replicated and nonreplicated DNA.

Question 19

You are working with a mixed population of cells that includes some cells expressing CD95 on their surfaces.Design an experimental protocol using Fluorescence-Activated Cell Sorting (FACS)to determine how many CD95-expressing cells are dividing at any given time.

Accepted Answer

Stain all the cells with a DNA dye and a

Question 20

The final separation of two daughter cells at the end of cytokinesis in animals is known as ________.

Accepted Answer

The answer of The final separation of two daughter cells...

Exam 24: The Cell Cycle and Mitosis

Cells grow primarily during which of the following cell-cycle phases?

Each of the following occurs during apoptosis of a cell except

Each of the following is true about cytochrome c in apoptosis except

A mutant cell in which sister chromatids get torn apart rather than separating correctly at anaphase most likely is deficient in

In an adult human stem cell that has a total of 48 chromosomes,how many chromatids are present at prophase of mitosis?

Each of the following provides evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole except

The cell-cycle phase that varies most in duration in various eukaryotic adult cell types is

Rapidly dividing embryonic cells shorten S-phase duration by increasing the number of ________.

Cell cycle studies have been facilitated by ________,a technique that allows rapid analysis and sorting of thousands or millions of cells.

A eukaryotic cell G2-M checkpoint assesses the status of

Each of the following statements regarding CD95-stimulated programmed cell death is true except

All of the following participate in apoptosis except

Which of the following families of proteins plays a central role in regulating the assembly and activation of the contractile ring?

Each of the following would inhibit cell progression through the cell cycle except

Starting with a diploid cell (2n = 4),illustrate the phases of mitosis with emphasis on the movement of chromosomes.

A centromere contains repeated DNA sequences known as ________.

The mechanism by which DNA is licensed to replicate only once during each S phase involves

You are working with a mixed population of cells that includes some cells expressing CD95 on their surfaces.Design an experimental protocol using Fluorescence-Activated Cell Sorting (FACS)to determine how many CD95-expressing cells are dividing at any given time.

The final separation of two daughter cells at the end of cytokinesis in animals is known as ________.

A Preview of Cell Biology

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: the Flow of Energy in the Cell

Enzymes: the Catalysts of Life

Membranes: Their Structure,function,and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

The Endomembrane System

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesions, cell Junctions, and Extracellular Structures

The Structural Basis of Cellular Information: Dna, chromosomes, and the Nucleus

DNA Replication, repair, and Recombination

Gene Expression: Ithe Genetic Code and Transcription

Gene Expression: Iiprotein Synthesis and Sorting

The Regulation of Gene Expression

Molecular Biology Techniques for Cell Biology

Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Iimessengers and Receptors

Sexual Reproduction,meiosis,and Genetic Recombination

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