Question 1

What is the major organic product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV A

Question 2

Organocuprate reagents (R2CuLi)react with several compounds.Which listed reaction is not correct?

Accepted Answer

A) Acid chlorides react with organocuprate reagents to form ketones. 
B) Epoxides react with organocuprate reagents to form alcohols. 
C) Alkyl halides react with organocuprate reagents to form coupling products containing a new carbon-carbon bond. 
D) Carbon dioxide reacts with organocuprate reagents to form carboxylic acids. 
A) Acid chlorides react with organocuprate reagents to form ketones. 
B) Epoxides react with organocuprate reagents to form alcohols. 
C) Alkyl halides react with organocuprate reagents to form coupling products containing a new carbon-carbon bond. 
D) Carbon dioxide reacts with organocuprate reagents to form carboxylic acids. D

Question 3

Identify the structure of the major organic product that results from the following reaction.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV B

Question 4

Which of the following descriptions does not apply to methylene?

Accepted Answer

A) Methylene is sp2 hybridized. 
B) Methylene is a neutral,reactive intermediate. 
C) Methylene is a radical intermediate. 
D) The formula of methylene is :CH2. 
A) Methylene is sp2 hybridized. 
B) Methylene is a neutral,reactive intermediate. 
C) Methylene is a radical intermediate. 
D) The formula of methylene is :CH2.

Question 5

As shown below,when cis-2-butene reacts with dichlorocarbene,only the cis-1,1-dichloro-2,3-dimethylcyclopropane is formed.What can we conclude about the nature of the reaction mechanism?

Accepted Answer

A) The mechanism is an SN1 mechanism. 
B) The mechanism is a concerted. 
C) The mechanism proceeds through a radical intermediate. 
D) The mechanism is an E2 mechanism. 
A) The mechanism is an SN1 mechanism. 
B) The mechanism is a concerted. 
C) The mechanism proceeds through a radical intermediate. 
D) The mechanism is an E2 mechanism.

Question 6

What is the major product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 7

Starting with chloroform,what reactions order and reagents are necessary to produce the following product?

Accepted Answer

A) [1] KOC(CH3)3,[2] trans-2-butene 
B) [1] KOC(CH3)3,[2] cis-2-butene 
C) [1] trans-2-butene,[2] KOC(CH3)3 
D) [1] cis-2-butene,[2] KOC(CH3)3 
A) [1] KOC(CH3)3,[2] trans-2-butene 
B) [1] KOC(CH3)3,[2] cis-2-butene 
C) [1] trans-2-butene,[2] KOC(CH3)3 
D) [1] cis-2-butene,[2] KOC(CH3)3

Question 8

Why is the Grubbs catalyst synthetically important?

Accepted Answer

A) Because it only requires dilute concentrations of the reactants 
B) Because it produces only stereospecific products 
C) Because it produces only stereoselective products 
D) Because it provides a synthetic pathway for ring-closing metathesis reactions 
A) Because it only requires dilute concentrations of the reactants 
B) Because it produces only stereospecific products 
C) Because it produces only stereoselective products 
D) Because it provides a synthetic pathway for ring-closing metathesis reactions

Question 9

Identify the products of the following reaction.

Accepted Answer

A) A 
B) B 
C) C 
D) D 
A) A 
B) B 
C) C 
D) D

Question 10

What would be the starting material for the following product that was made via a Grubbs catalyst?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 11

Compound X can be synthesized via a ring-closing metathesis reaction when treated with a Grubbs' catalyst.What is a possible structure of the starting material for this reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 12

Identify the structure of the major organic product that results from the following reaction.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 13

What is the major organic product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) None of the choices is correct. 
A) I 
B) II 
C) III 
D) None of the choices is correct.

Question 14

What starting material could yield the following compound if Simmons-Smith conditions were used?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 15

Choose the statement below that is not true about the Suzuki reaction.

Accepted Answer

A) The product of the Suzuki reaction is completely stereospecific. 
B) The Suzuki reaction involves both an organoborane reagent and an organopalladium catalyst. 
C) The Suzuki reaction forms more highly substituted alkenes. 
D) The Suzuki reaction involves an oxidative addition followed by a reductive elimination. 
A) The product of the Suzuki reaction is completely stereospecific. 
B) The Suzuki reaction involves both an organoborane reagent and an organopalladium catalyst. 
C) The Suzuki reaction forms more highly substituted alkenes. 
D) The Suzuki reaction involves an oxidative addition followed by a reductive elimination.

Question 16

Identify the starting material that would be used to form the following product in a ring-closing metathesis reaction utilizing a Grubbs catalyst?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 17

Which of the following is true about the use of the Grubbs catalyst?

Accepted Answer

A) The Grubbs catalyst is used in carbon-carbon coupling reactions. 
B) The Grubbs catalyst is used in alkene metathesis. 
C) The Grubbs catalyst is used in carbene formation. 
D) The Grubbs catalyst is used with palladium as a co-catalyst. 
A) The Grubbs catalyst is used in carbon-carbon coupling reactions. 
B) The Grubbs catalyst is used in alkene metathesis. 
C) The Grubbs catalyst is used in carbene formation. 
D) The Grubbs catalyst is used with palladium as a co-catalyst.

Question 18

What is the missing reactant in the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 19

Identify the structure of the organic product Y formed in the following reaction sequence.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 20

Starting with chloroform,what reactions order and reagents are necessary to produce the following product and its enantiomer?

Accepted Answer

A) [1] KOC(CH3)3,[2] trans-2-butene 
B) [1] KOC(CH3)3,[2] cis-2-butene 
C) [1] trans-2-butene,[2] KOC(CH3)3 
D) [1] cis-2-butene,[2] KOC(CH3)3 
A) [1] KOC(CH3)3,[2] trans-2-butene 
B) [1] KOC(CH3)3,[2] cis-2-butene 
C) [1] trans-2-butene,[2] KOC(CH3)3 
D) [1] cis-2-butene,[2] KOC(CH3)3

Exam 24: Carbon-Carbon Bond-Forming Reactions in Organic Synthesis

What is the major organic product of the following reaction?

Organocuprate reagents (R2CuLi)react with several compounds.Which listed reaction is not correct?

Identify the structure of the major organic product that results from the following reaction.

Which of the following descriptions does not apply to methylene?

As shown below,when cis-2-butene reacts with dichlorocarbene,only the cis-1,1-dichloro-2,3-dimethylcyclopropane is formed.What can we conclude about the nature of the reaction mechanism?

What is the major product of the following reaction?

Starting with chloroform,what reactions order and reagents are necessary to produce the following product?

Why is the Grubbs catalyst synthetically important?

Identify the products of the following reaction.

What would be the starting material for the following product that was made via a Grubbs catalyst?

Compound X can be synthesized via a ring-closing metathesis reaction when treated with a Grubbs' catalyst.What is a possible structure of the starting material for this reaction?

Identify the structure of the major organic product that results from the following reaction.

What is the major organic product of the following reaction?

What starting material could yield the following compound if Simmons-Smith conditions were used?

Choose the statement below that is not true about the Suzuki reaction.

Identify the starting material that would be used to form the following product in a ring-closing metathesis reaction utilizing a Grubbs catalyst?

Which of the following is true about the use of the Grubbs catalyst?

What is the missing reactant in the following reaction?

Identify the structure of the organic product Y formed in the following reaction sequence.

Starting with chloroform,what reactions order and reagents are necessary to produce the following product and its enantiomer?

Structure and Bonding

Acids and Bases

Introduction to Organic Molecules and Functional Groups

Alkanes

Stereochemistry

Understanding Organic Reactions

Alkyl Halides and Nucleophilic Substitution

Alkyl Halides and Elimination Reactions

Alcohols,ethers,and Related Compounds

Alkenes and Addition Reactions

Alkynes and Synthesis

Oxidation and Reduction

Radical Reactions

Conjugation,resonance,and Dienes

Benzene and Aromatic Compounds

Reactions of Aromatic Compounds

Introduction to Carbonyl Chemistry; Organometallic Reagents; Oxidation and Reduction

Aldehydes and Ketones - Nucleophilic Addition

Carboxylic Acids and the Acidity of the O-H Bond

Carboxylic Acids and Their Derivatives Nucleophilic Acyl Substitution

Substitution Reactions of Carbonyl Compounds at the a Carbon

Carbonyl Condensation Reactions

Amines

Pericyclic Reactions

Carbohydrates

Amino Acids and Proteins

Synthetic Polymers

Lipids

Spectroscopy A: Mass Spectrometry

Spectroscopy B: Infrared Spectroscopy

Spectroscopy C: Nuclear Magnetic Resonance Spectroscopy

Filters

Organocuprate reagents (R₂CuLi)react with several compounds.Which listed reaction is not correct?