Question 1

Which of the following is not a part of TFIID?

Accepted Answer

A) -45 region 
B) TBP 
C) TBP-associated factors 
D) -45 region and TBP 
E) TBP and TBP-associated factors 
A) -45 region 
B) TBP 
C) TBP-associated factors 
D) -45 region and TBP 
E) TBP and TBP-associated factors

Question 2

Predict the consequence of blocking the action of TFIIF.

Accepted Answer

A) The DAB complex will not form. 
B) TFIIA will not bind to TFIID. 
C) Polymerase may not bind to the DAB complex. 
D) The DAB complex will not form and TFIIA will not bind to TFIID are correct. 
E) TFIIA will not bind to TFIID and polymerase may not bind to the DAB complex are correct. 
A) The DAB complex will not form. 
B) TFIIA will not bind to TFIID. 
C) Polymerase may not bind to the DAB complex. 
D) The DAB complex will not form and TFIIA will not bind to TFIID are correct. 
E) TFIIA will not bind to TFIID and polymerase may not bind to the DAB complex are correct.

Question 3

Which of the following is a possible effect of creating a mutant cell line with reduced levels of TAF1?

Accepted Answer

A) Initiation complex would be slow to form. 
B) Polymerase II will show weak binding to the promoter. 
C) Proofreading activity will be impaired. 
D) The DAB complex will dissociate. 
E) None of the choices are correct. 
A) Initiation complex would be slow to form. 
B) Polymerase II will show weak binding to the promoter. 
C) Proofreading activity will be impaired. 
D) The DAB complex will dissociate. 
E) None of the choices are correct.

Question 4

The following are features of TAF1:

Accepted Answer

A) contains DNase I domain. 
B) is a histone acetyltransferase. 
C) is a protein kinase. 
D) contains DNase I domain and is a histone acetyltransferase. 
E) is a histone acetyltransferase and is a protein kinase. 
A) contains DNase I domain. 
B) is a histone acetyltransferase. 
C) is a protein kinase. 
D) contains DNase I domain and is a histone acetyltransferase. 
E) is a histone acetyltransferase and is a protein kinase.

Question 5

Human SL1 is composed of all of the following except

Accepted Answer

A) TBP. 
B) TAFI30. 
C) TAFI 110. 
D) TAFI63. 
E) TAFI48. 
A) TBP. 
B) TAFI30. 
C) TAFI 110. 
D) TAFI63. 
E) TAFI48.

Question 6

The carboxyl-terminal domain of polymerase is phosphorylated prior to the formation of the initiation complex.

Accepted Answer

A) True 
 B)False

Question 7

Which of the following would you expect to bind to a chromatography column made of a resin conjugated to UBF?

Accepted Answer

A) Sp1 
B) SL1 
C) TFIIB 
D) TFIIH 
E) TFIIE 
A) Sp1 
B) SL1 
C) TFIIB 
D) TFIIH 
E) TFIIE

Question 8

Select a likely effect of reducing the level of TIF-IB from a yeast cell line.

Accepted Answer

A) Polymerase will not recognize the promoter. 
B) The level of transcription initiation from class I promoters will be low. 
C) Polymerase will not associate with DAB. 
D) Polymerase will not recognize the promoter and the level of transcription initiation from class I promoters will be low are correct. 
E) The level of transcription initiation from class I promoters will be low and polymerase will not associate with DAB are correct. 
A) Polymerase will not recognize the promoter. 
B) The level of transcription initiation from class I promoters will be low. 
C) Polymerase will not associate with DAB. 
D) Polymerase will not recognize the promoter and the level of transcription initiation from class I promoters will be low are correct. 
E) The level of transcription initiation from class I promoters will be low and polymerase will not associate with DAB are correct.

Question 9

TFIID collaborates with TFIIA to bind to the TATA box.

Accepted Answer

A) True 
 B)False

Which of the following is not a part of TFIID?

Predict the consequence of blocking the action of TFIIF.

Which of the following is a possible effect of creating a mutant cell line with reduced levels of TAF1?

The following are features of TAF1:

Human SL1 is composed of all of the following except

The carboxyl-terminal domain of polymerase is phosphorylated prior to the formation of the initiation complex.

Which of the following would you expect to bind to a chromatography column made of a resin conjugated to UBF?

Select a likely effect of reducing the level of TIF-IB from a yeast cell line.

TFIID collaborates with TFIIA to bind to the TATA box.

A Brief History

The Molecular Nature of Genes

An Introduction to Gene Function

Molecular Cloning Methods

Molecular Tools for Studying Genes and Gene Activity

The Mechanism of Transcription in Bacteria

Operons: Fine Control of Bacterial Transcription

Major Shifts in Bacterial Transcription

Dna-Protein Interactions in Bacteria

Eukaryotic Rna Polymerases and Their Promoters

Transcription Activators in Eukaryotes

Chromatin Structure and Its Effect on Transcription

Rna Processing I: Splicing

Rna Processing II: Capping and Polyadenylation

Rna Processing: Other Post-Transcriptional Events

The Mechanism of Translation I: Initiation

The Mechanism of Translation II: Elongation and Termination

Ribosomes and Transfer Rna

Dna Replication,damage and Repair

Dna Replication II: Detailed Mechanism

Homologous Recombination

Transposition

Introduction to Genomics: Dna Sequencing on a Genomic Scale

Genomics II: Functional Genomics,proteomics and Bioinformatics

Filters

Exam 11: General Transcription Factors in Eukaryotes

Which of the following is not a part of TFIID?

Predict the consequence of blocking the action of TFIIF.

Which of the following is a possible effect of creating a mutant cell line with reduced levels of TAF1?

The following are features of TAF1:

Human SL1 is composed of all of the following except

The carboxyl-terminal domain of polymerase is phosphorylated prior to the formation of the initiation complex.

Which of the following would you expect to bind to a chromatography column made of a resin conjugated to UBF?

Select a likely effect of reducing the level of TIF-IB from a yeast cell line.

TFIID collaborates with TFIIA to bind to the TATA box.

A Brief History

The Molecular Nature of Genes

An Introduction to Gene Function

Molecular Cloning Methods

Molecular Tools for Studying Genes and Gene Activity

The Mechanism of Transcription in Bacteria

Operons: Fine Control of Bacterial Transcription

Major Shifts in Bacterial Transcription

Dna-Protein Interactions in Bacteria

Eukaryotic Rna Polymerases and Their Promoters

Transcription Activators in Eukaryotes

Chromatin Structure and Its Effect on Transcription

Rna Processing I: Splicing

Rna Processing II: Capping and Polyadenylation

Rna Processing: Other Post-Transcriptional Events

The Mechanism of Translation I: Initiation

The Mechanism of Translation II: Elongation and Termination

Ribosomes and Transfer Rna

Dna Replication,damage and Repair

Dna Replication II: Detailed Mechanism

Homologous Recombination

Transposition

Introduction to Genomics: Dna Sequencing on a Genomic Scale

Genomics II: Functional Genomics,proteomics and Bioinformatics

Filters