Exam 22: Homologous Recombination

West and colleagues used gel mobility shift assays to demonstrate that __________ could bind to and resolve Holliday junctions.

Gene conversion usually only occurs between nonallelic genes such as the MAT genes used to determine mating type in yeasts.

In eukaryotes,_______ often includes homologous recombination as a way to increase genetic variation.

A conserved tyrosine residue is likely to be the catalytic amino acid in Spo11 and homologous proteins.

Branch migration is a spontaneous process that takes place after a Holliday junction is formed.

Since RecA is such a versatile protein,RecBCD is not really necessary for homologous recombination to occur.

RecBCD protein has ______________ activity that can nick dsDNA.

A ________ double helix is different than a Watson-Crick double helix in that the two strands are aligned side by side instead of intertwined.

Holliday junctions are intermediates in RecBCD recombination in E.coli.

___________ protein greatly enhances the binding of RecA to single stranded DNA.