Question 1

Photolyase functions to:

Accepted Answer

A)   repair pyrimidine dimers.
B)   remove damaged bases.
C)   ligate single-strand breaks.
D)   All of the above.
E)   None of the above. A

Question 2

Describe the consequences of incorrect DNA replication or DNA damage.

Accepted Answer

The most serious consequences are cell death, cell transformation, and blockage of DNA replication. The changes in DNA can also be inherited and passed on to future generations.

Question 3

___________________ is the enzyme that converts polycyclic aromatic hydrocarbons into a reactive epoxide that alkylates the N-7 of guanine.

Accepted Answer

cytochrome P450

Question 4

The human genetic skin disease that is caused by a mutation in components of the human nucleotide-excision-repair pathway is called ___________________.

Accepted Answer

The answer of The human genetic skin disease that is...

Question 5

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are involved in joining DNA molecules together.

Accepted Answer

A)  uracil
B)  DNA ligase
C)  Huntington disease
D)  Ames
E)  xeroderma pigmentosumF) tumor-suppressor genesG) trinucleotide repeatsH) skin carcinomaI) mutagenJ) direct repairK) indirect repairL) photolyase

Question 6

The process whereby two daughter molecules of DNA are formed by the exchange of genetic material between two parent molecules is known as:

Accepted Answer

A)   chemical modification.
B)   recombination.
C)   alkylation.
D)   dimerization.
E)   None of the above.

Question 7

Why is thymine used in DNA instead of uracil?

Accepted Answer

The answer of Why is thymine used in DNA instead...

Question 8

A photoreactivating enzyme is called ___________________.

Accepted Answer

The answer of A photoreactivating enzyme is called ___________________....

Question 9

What role does the protein RAD51 play in recombination?

Accepted Answer

The answer of What role does the protein RAD51 play...

Question 10

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are caused by expanded trinucleotide repeats.

Accepted Answer

A)  uracil
B)  DNA ligase
C)  Huntington disease
D)  Ames
E)  xeroderma pigmentosumF) tumor-suppressor genesG) trinucleotide repeatsH) skin carcinomaI) mutagenJ) direct repairK) indirect repairL) photolyase

Question 11

X-rays cause damage to DNA by inducing ___________________.

Accepted Answer

The answer of X-rays cause damage to DNA by inducing...

Question 12

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is a rare skin disease caused by the inability to correct for UV damage to skin DNA.

Accepted Answer

A)  uracil
B)  DNA ligase
C)  Huntington disease
D)  Ames
E)  xeroderma pigmentosumF) tumor-suppressor genesG) trinucleotide repeatsH) skin carcinomaI) mutagenJ) direct repairK) indirect repairL) photolyase

Question 13

What does the phrase "recombination of genetic material" refer to?

Accepted Answer

The answer of What does the phrase "recombination of genetic...

Question 14

Light-driven DNA damage results in ___________________.

Accepted Answer

The answer of Light-driven DNA damage results in ___________________....

Question 15

Damage to DNA may result in:

Accepted Answer

A)   cell death.
B)   cell transformation.
C)   changes in inherited sequences.
D)   blockage of DNA replication.
E)   All of the above.

Question 16

In E. coli, mismatch repair involves:

Accepted Answer

A)   recognition of mismatched pair by MutS.
B)   removal of a mismatched nucleotide by DNA polymerase III.
C)   cleavage of the backbone by MutH.
D)   A and C
E)   A, B, and C.

Question 17

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is the process for correcting for base-pair mismatches without excising bases.

Accepted Answer

A)  uracil
B)  DNA ligase
C)  Huntington disease
D)  Ames
E)  xeroderma pigmentosumF) tumor-suppressor genesG) trinucleotide repeatsH) skin carcinomaI) mutagenJ) direct repairK) indirect repairL) photolyase

Question 18

Describe the Ames test.

Accepted Answer

The answer of Describe the Ames test....

Question 19

Name the types of DNA repair, categorized in groups.

Accepted Answer

The answer of Name the types of DNA repair, categorized...

Question 20

Tumor-suppressor genes have a dominant negative genetic trait. What does this mean?

Accepted Answer

The answer of Tumor-suppressor genes have a dominant negative genetic...

Exam 35: DNA Repair and Recombination

Photolyase functions to:

Describe the consequences of incorrect DNA replication or DNA damage.

___________________ is the enzyme that converts polycyclic aromatic hydrocarbons into a reactive epoxide that alkylates the N-7 of guanine.

The human genetic skin disease that is caused by a mutation in components of the human nucleotide-excision-repair pathway is called ___________________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are involved in joining DNA molecules together.

The process whereby two daughter molecules of DNA are formed by the exchange of genetic material between two parent molecules is known as:

Why is thymine used in DNA instead of uracil?

A photoreactivating enzyme is called ___________________.

What role does the protein RAD51 play in recombination?

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are caused by expanded trinucleotide repeats.

X-rays cause damage to DNA by inducing ___________________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is a rare skin disease caused by the inability to correct for UV damage to skin DNA.

What does the phrase "recombination of genetic material" refer to?

Light-driven DNA damage results in ___________________.

Damage to DNA may result in:

In E. coli, mismatch repair involves:

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is the process for correcting for base-pair mismatches without excising bases.

Describe the Ames test.

Name the types of DNA repair, categorized in groups.

Tumor-suppressor genes have a dominant negative genetic trait. What does this mean?