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Mice Lacking IL-15 or the IL-15R α\alpha Chain Have Substantially Reduced Numbers of Type B IELs, Including

Question 12

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Mice lacking IL-15 or the IL-15R α\alpha chain have substantially reduced numbers of type b IELs, including both α\alpha : β\beta and γ\gamma : δ\delta T-cell receptor-positive subsets. Normal numbers of type b IELs can be restored in il15-/- mice by cell-type specific expression of IL-15 in:


A) Thymic medullary epithelial cells
B) Thymic cortical epithelial cells
C) Dendritic cells
D) CD8 α\alphaα\alpha + T cells
E) Intestinal epithelial cells

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