A 77-Year-Old Female Is Having Problems Sleeping, and Her Physician

A 77-year-old female is having problems sleeping, and her physician prescribed flurazepam, a sleep aid. The patient reports that she feels "groggy" for about 2 days after having taken the drug. Flurazepam is

A) destroyed by the acidic conditions in the stomach
B) inactivated by pepsin in the stomach
C) denatured by trypsin in the duodenum
D) inactivated by the P-450 enzyme system of the liver
E) destroyed by proteasomes in the jejunum

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