Question 1

The nurse is preparing to administer furosemide to a patient who takes digoxin.The nurse will plan to monitor the patient for

Accepted Answer

A)   digoxin toxicity.
B)   decreased digoxin effects.
C)   erythromycin toxicity.
D)   decreased erythromycin effects. A

Question 2

The nurse is preparing to administer a drug and learns that it binds to protein at a rate of 90%.The patient's serum albumin level is low.The nurse will observe the patient for

Accepted Answer

A)   decreased drug absorption.
B)   decreased drug interactions.
C)   decreased drug toxicity.
D)   increased drug effects. D

Question 3

A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment.How will the nurse give the drug?

Accepted Answer

A)   On an empty stomach
B)   With a full glass of water
C)   With food
D)   With high-fat food C

Question 4

A patient who takes a drug that undergoes gastric absorption will begin taking an opioid analgesic after sustaining an injury in a motor vehicle accident.The nurse will observe the patient closely for which effects?

Accepted Answer

A)   Decreased effects of the first drug
B)   Increased effects of the first drug
C)   Decreased effects of the narcotic
D)   Increased effects of the narcotic

Question 5

A young adult female patient who takes a combination oral contraceptive (OCP)will begin taking an antibiotic.When teaching the patient about this medication,the nurse will

Accepted Answer

A)   recommend using a backup method of contraception.
B)   suggest that she switch to an injectable form of contraception.
C)   tell her that the antibiotic is less effective if she is taking OCPs.
D)   tell her the antibiotic has a greater risk for toxicity while taking OCPs.

Question 6

The nurse is preparing to administer an oral medication that is water soluble.The nurse understands that this drug

Accepted Answer

A)   must be taken on an empty stomach.
B)   requires active transport for absorption.
C)   should be taken with fatty foods.
D)   will readily diffuse into the GI tract.

Question 7

The nurse gives 800 mg of a drug that has a half-life of 8 hours.How much drug will be left in the body in 24 hours if no additional drug is given?

Accepted Answer

A)   None
B)   50 mg
C)   100 mg
D)   200 mg

Question 8

The nurse is explaining to the patient why a nonspecific drug has so many side effects.Which statement by the patient indicates a need for further teaching?

Accepted Answer

A)   "Non-specific drugs can affect specific receptor types in different body tissues."
B)   "Non-specific drugs can affect a variety of receptor types in similar body tissues."
C)   "Non-specific drugs can affect hormone secretion as well as cellular functions."
D)   "Non-specific drugs require higher doses than specific drugs to be effective."

Question 9

The nurse administers albuterol to a patient who has asthma.The albuterol acts by stimulating beta2-adrenergic receptors to cause bronchodilation.The nurse understands that albuterol is a beta-adrenergic

Accepted Answer

A)   agonist.
B)   antagonist.
C)   inhibitor.
D)   depressant.

Question 10

The provider has ordered amoxicillin with clavulanate (Augmentin)for a child who has otitis media.The child's parent asks why this drug is necessary when amoxicillin is less expensive.The nurse will explain that clavulanate is added to amoxicillin because it

Accepted Answer

A)   binds with albumin to increase the amount of available amoxicillin.
B)   broadens the spectrum of amoxicillin by inhibiting bacterial enzymes.
C)   inhibits hepatic blood flow, leading to increased serum drug levels of amoxicillin.
D)   inhibits the excretion of amoxicillin by interfering with renal function.

Question 11

The nurse prepares to change a patient's medication from an IV to an oral form and notes that the oral form is ordered in a higher dose.The nurse understands that this is due to differences in

Accepted Answer

A)   bioavailability.
B)   pinocytosis.
C)   protein binding.
D)   tachyphylaxis.

Question 12

A patient will receive penicillin to treat an infection.The provider orders probenecid (Probalan),a medication to treat gout,even though the patient does not have gout.Which action by the nurse is correct?

Accepted Answer

A)   Administer the drug since the provider ordered it.
B)   Recognize that it is being given prophylactically.
C)   Refuse to administer the medication since it is not indicated.
D)   Verify that it is being given for its secondary action.

Question 13

A patient has been taking warfarin (Coumadin),which is highly protein-bound.The patient will begin taking gemfibrozil,which is also highly protein-bound.The nurse will observe the patient closely for

Accepted Answer

A)   decreased effects of warfarin.
B)   increased effects of warfarin.
C)   decreased effects of gemfibrozil.
D)   decreased effects of both drugs.

Question 14

A patient is taking phenytoin to prevent seizures.The nurse knows that phenytoin is highly protein-bound and has sedative's side effects.The nurse reviews the patient's chart and notes a low serum albumin.The nurse will notify the provider and observe the patient for which effects?

Accepted Answer

A)   Decreased sedative effects
B)   Increased sedative effects
C)   Increased seizures
D)   No change in effects

Question 15

The nurse is preparing to administer meperidine (Demerol),which is an opioid analgesic,and promethazine (Phenergan),which is an antiemetic and antihistamine.The nurse understands that these drugs are given in combination for which reason?

Accepted Answer

A)   They have antagonistic effects to reduce nausea.
B)   They have additive effects to enhance analgesia.
C)   They have potentiating effects to decrease an allergic response.
D)   They have synergistic effects to increase sedation.

Question 16

The nurse is teaching a patient who will be discharged home with a prescription for an enteric-coated tablet.Which statement by the patient indicates understanding of the teaching?

Accepted Answer

A)   "I may crush the tablet and put it in applesauce to improve absorption."
B)   "I should consume acidic foods to enhance absorption of this medication."
C)   "I should expect a delay in onset of the drug's effects after taking the tablet."
D)   "I should take this medication with high-fat foods to improve its action."

Question 17

The nurse is preparing to teach a patient who will begin taking a monoamine oxidase (MAO)inhibitor.What is most important when teaching patients about MAO inhibitors?

Accepted Answer

A)   Emphasizing the importance of potassium intake
B)   Giving detailed drug information
C)   Reviewing dietary guidelines
D)   Providing a schedule for medication administration

Question 18

A patient who takes the anticoagulant warfarin will begin taking the anticonvulsant drug carbamazepine.The nurse reviews the drug information for these drugs and learns that carbamazepine is a hepatic enzyme inducer.The nurse anticipates that the provider will make which dosage adjustment?

Accepted Answer

A)   Decrease the dose of carbamazepine
B)   Increase the dose of carbamazepine
C)   Decrease the dose of warfarin
D)   Increase the dose of warfarin

Question 19

A patient has been taking a drug for several years and tells the nurse it is no longer working.The nurse learns that the patient has recently begun taking an over-the-counter (OTC)antacid medication.What does the nurse suspect is occurring?

Accepted Answer

A)   An adverse drug reaction
B)   A drug interaction
C)   Drug incompatibility
D)   Drug tolerance

Question 20

The nurse is preparing to administer the first dose of digoxin (Lanoxin)to a patient and notes that the dose ordered is much higher than the usual recommended dose.Which action will the nurse perform?

Accepted Answer

A)   Administer the dose as ordered.
B)   Give the dose and monitor for toxicity.
C)   Hold the dose until reviewing it with the provider.
D)   Refuse to give the dose.

Exam 2: Pharmacokinetics,Pharmacodynamics,and Pharmacogenetics

The nurse is preparing to administer furosemide to a patient who takes digoxin.The nurse will plan to monitor the patient for

The nurse is preparing to administer a drug and learns that it binds to protein at a rate of 90%.The patient's serum albumin level is low.The nurse will observe the patient for

A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment.How will the nurse give the drug?

A patient who takes a drug that undergoes gastric absorption will begin taking an opioid analgesic after sustaining an injury in a motor vehicle accident.The nurse will observe the patient closely for which effects?

A young adult female patient who takes a combination oral contraceptive (OCP) will begin taking an antibiotic.When teaching the patient about this medication,the nurse will

The nurse is preparing to administer an oral medication that is water soluble.The nurse understands that this drug

The nurse gives 800 mg of a drug that has a half-life of 8 hours.How much drug will be left in the body in 24 hours if no additional drug is given?

The nurse is explaining to the patient why a nonspecific drug has so many side effects.Which statement by the patient indicates a need for further teaching?

The nurse administers albuterol to a patient who has asthma.The albuterol acts by stimulating beta₂-adrenergic receptors to cause bronchodilation.The nurse understands that albuterol is a beta-adrenergic

The provider has ordered amoxicillin with clavulanate (Augmentin) for a child who has otitis media.The child's parent asks why this drug is necessary when amoxicillin is less expensive.The nurse will explain that clavulanate is added to amoxicillin because it

The nurse prepares to change a patient's medication from an IV to an oral form and notes that the oral form is ordered in a higher dose.The nurse understands that this is due to differences in

A patient will receive penicillin to treat an infection.The provider orders probenecid (Probalan) ,a medication to treat gout,even though the patient does not have gout.Which action by the nurse is correct?

A patient has been taking warfarin (Coumadin) ,which is highly protein-bound.The patient will begin taking gemfibrozil,which is also highly protein-bound.The nurse will observe the patient closely for

A patient is taking phenytoin to prevent seizures.The nurse knows that phenytoin is highly protein-bound and has sedative's side effects.The nurse reviews the patient's chart and notes a low serum albumin.The nurse will notify the provider and observe the patient for which effects?

The nurse is preparing to administer meperidine (Demerol) ,which is an opioid analgesic,and promethazine (Phenergan) ,which is an antiemetic and antihistamine.The nurse understands that these drugs are given in combination for which reason?

The nurse is teaching a patient who will be discharged home with a prescription for an enteric-coated tablet.Which statement by the patient indicates understanding of the teaching?

The nurse is preparing to teach a patient who will begin taking a monoamine oxidase (MAO) inhibitor.What is most important when teaching patients about MAO inhibitors?

A patient who takes the anticoagulant warfarin will begin taking the anticonvulsant drug carbamazepine.The nurse reviews the drug information for these drugs and learns that carbamazepine is a hepatic enzyme inducer.The nurse anticipates that the provider will make which dosage adjustment?

A patient has been taking a drug for several years and tells the nurse it is no longer working.The nurse learns that the patient has recently begun taking an over-the-counter (OTC) antacid medication.What does the nurse suspect is occurring?

The nurse is preparing to administer the first dose of digoxin (Lanoxin) to a patient and notes that the dose ordered is much higher than the usual recommended dose.Which action will the nurse perform?