Question 1

Which of the following statements represents the primary advantage of the use of metered-dose inhalers (MDIs)?

Accepted Answer

A) The inhaled dose can be accurately measured. 
B) They are difficult to use properly,and they can be abused. 
C) The onset of action is unpredictable. 
D) The bronchodilator effect is less than that of a comparable oral dose.

Question 2

The primary advantage of second-generation H₁ agents is that they are less likely to have which of the following pharmacologic effects of first-generation H₁ antihistamines?

Accepted Answer

A) Antihistaminic 
B) Antiserotonergic 
C) Anticholinergic 
D) Sedative

Question 3

Which of the following groups of medications are considered first-line treatment for chronic obstructive pulmonary disease (COPD)?

Accepted Answer

A) b-adrenergic agonists 
B) Anticholinergics 
C) Methylxanthines 
D) Leukotriene (LT)antagonists

Question 4

Asthma is characterized by _____ airway obstruction and is associated with reduction in _____ airflow.

Accepted Answer

A) reversible;inspiratory 
B) reversible;expiratory 
C) irreversible;inspiratory 
D) irreversible;expiratory

Question 5

Which of the following drugs is a mast cell stabilizer?

Accepted Answer

A) Ipratropium bromide (Atrovent) 
B) Montelukast (Singulair) 
C) Cromolyn sodium (Nasalcrom) 
D) Azelastine (Astelin)

Question 6

Which of the following types of medication are considered first-line therapy for the treatment of moderate to severe allergic rhinitis?

Accepted Answer

A) Leukotriene modifiers 
B) Intranasal corticosteroids 
C) Mast cell stabilizers 
D) Intranasal decongestants

Question 7

Which type of drug is used in conjunction with low-dose corticosteroids to treat patients with persistent asthma that is not well controlled with low-dose inhaled corticosteroids?

Accepted Answer

A) Corticosteroids 
B) Leukotriene modifiers 
C) Long-acting β₂ -agonists 
D) Mast cell degranulation inhibitors 
E) Anti-interleukin-5 antibodies

Question 8

Which one of the following recommendations would you not make to your patients with asthma?

Accepted Answer

A) Bring your inhaler (albuterol)to the dental appointment. 
B) Rinse after using your corticosteroid inhaler. 
C) Avoid erythromycin. 
D) Avoid aspirin. 
E) Avoid acetaminophen.

Question 9

The first line of treatment for intermittent asthma is a

Accepted Answer

A) short-acting β₂ -adrenergic agonist. 
B) long-acting β₂ -adrenergic agonist. 
C) corticosteroid. 
D) mast cell degranulation inhibitor. 
E) methylxanthine.

Question 10

Which of the following symptoms is the most common side effect associated with the older antihistamines? (Please note: all are associated,but one is most common)

Accepted Answer

A) Nausea 
B) Xerostomia 
C) Sedation 
D) Constipation

Question 11

Ipratropium bromide (Atrovent)is an intranasal _____ drug.

Accepted Answer

A) adrenergic 
B) cholinergic 
C) antiadrenergic 
D) anticholinergic

Question 12

A spacer is often placed between the metered-dose inhaler and the mouth to decrease the amount of drug delivered to the lungs.

Accepted Answer

A) True 
 B)False

Question 13

Cromolyn sodium works by blocking acetylcholine receptors.

Accepted Answer

A) True 
 B)False

Question 14

Allergic rhinitis is primarily associated with immunoglobulin A.

Accepted Answer

A) True 
 B)False

Question 15

Orally inhaled corticosteroids produce an immediate benefit in an acute asthma attack.

Accepted Answer

A) True 
 B)False

Question 16

Leukotriene modifiers are used to manage patients with _____ that is not controlled byβ₂-agonists and corticosteroid inhibitors.

Accepted Answer

A) emphysema 
B) asthma 
C) chronic bronchitis 
D) acute bronchitis

Question 17

Nasal decongestants are

Accepted Answer

A) alpha-adrenergic agonists. 
B) alpha-adrenergic antagonists. 
C) beta-adrenergic agonists. 
D) beta-adrenergic antagonists.

Question 18

Researchers have suggested that oxygen be limited to less than 3 L/min for patients with severe COPD.

Accepted Answer

A) True 
 B)False

Question 19

Montelukast (Singulair)has been associated with postmarketing reports of psychiatric symptoms.

Accepted Answer

A) True 
 B)False

Question 20

Which of the following statements is true of omalizumab (Xolair)?

Accepted Answer

A) It is a recombinant humanized monoclonal antibody. 
B) It prevents IgE from binding to mast cells and basophils. 
C) It is administered by inhalation. 
D) Both A and B are true. 
E) Both B and C are true.

Exam 17: Drugs for the Treatment of Respiratory Disorders and Allergic Rhinitis

Which of the following statements represents the primary advantage of the use of metered-dose inhalers (MDIs) ?

The primary advantage of second-generation H₁ agents is that they are less likely to have which of the following pharmacologic effects of first-generation H₁ antihistamines?

Which of the following groups of medications are considered first-line treatment for chronic obstructive pulmonary disease (COPD) ?

Asthma is characterized by _ airway obstruction and is associated with reduction in _ airflow.

Which of the following drugs is a mast cell stabilizer?

Which of the following types of medication are considered first-line therapy for the treatment of moderate to severe allergic rhinitis?

Which type of drug is used in conjunction with low-dose corticosteroids to treat patients with persistent asthma that is not well controlled with low-dose inhaled corticosteroids?

Which one of the following recommendations would you not make to your patients with asthma?

The first line of treatment for intermittent asthma is a

Which of the following symptoms is the most common side effect associated with the older antihistamines? (Please note: all are associated,but one is most common)

Ipratropium bromide (Atrovent) is an intranasal _____ drug.

A spacer is often placed between the metered-dose inhaler and the mouth to decrease the amount of drug delivered to the lungs.

Cromolyn sodium works by blocking acetylcholine receptors.

Allergic rhinitis is primarily associated with immunoglobulin A.

Orally inhaled corticosteroids produce an immediate benefit in an acute asthma attack.

Leukotriene modifiers are used to manage patients with _____ that is not controlled byβ₂-agonists and corticosteroid inhibitors.

Nasal decongestants are

Researchers have suggested that oxygen be limited to less than 3 L/min for patients with severe COPD.

Montelukast (Singulair)has been associated with postmarketing reports of psychiatric symptoms.

Which of the following statements is true of omalizumab (Xolair) ?