The Patient Presents with Acute Leukemia

The patient presents with acute leukemia.The blast morphology is of neutrophil lineage with Auer rods and pseudo-Pelger-Huët nuclei; the immunophenotype is positive for CD33, CD13, CD34, and CD56 with a positive TdT, myeloperoxidase, and Sudan Black B.Cytogenetic analysis reveals a t(8;21) (q22;q22) translocation in the majority of the blasts.Which classification of AML best fits this morphology, immunophenotyping, and cytotechemistry?

A) AML not otherwise categorized
B) AML with multilineage dysplasia
C) AML with recurrent genetic abnormalities
D) AML, therapy-related

Correct Answer:

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