Select the Best Statement from the Choices Below to Describe

Select the best statement from the choices below to describe the pathogenesis of PNH.

A) Increased hemolytic episodes are produced as a result of complement binding to erythrocytes via IgG antibodies in cold temperatures.
B) Increased hemolytic episodes are produced as a result of missing cell membrane proteins that regulate complement activation.
C) Increased hemolytic episodes are produced as a result of missing enzymes necessary for ATP production in erythrocytes.
D) Increased hemolytic episodes are produced as a result of initiation of an immune response against erythrocytes.

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