A Sample Demonstrates a DAT Profile That Is Positive with Polyspecific

A sample demonstrates a DAT profile that is positive with polyspecific AHG, negative with anti-IgG, and positive with anti-C3. If the Donath-Landsteiner test was also positive, what should the clinical laboratory professional do?

A) Perform an elution and antibody panel
B) Confer with the supervisor regarding the possibility of PCH
C) Request a serum sample for antibody screen
D) Perform a cold agglutinin test

Correct Answer:

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